Portal de investigação
Rapid detection of aneuploidies in prenatal diagnostics
Dados básicos
- Código:
- Estudo Clínico Académico
- Protocolo:
- Estudo Clínico Académico
- EUDRACT:
- NCT:
- Centro:
- Dotação:
- Ano de início:
- 2021
- Ano de conclusão:
Objectivos do projeto
Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários
Documentos
- Não há documentos
Participantes
Unidades de investigação
Stakeholders - Promotores
Outputs do ensaio clínico
Actionable secondary findings following exome sequencing of 836 non-obstructive azoospermia cases and their value in patient management
Kasak, L; (...); Laan, M
Article. 10.1093/humrep/deac100. 2022
ANALYSIS OF EPIGENETIC REGULATORS IN SPERMATOZOA FROM INFERTILE PATIENTS
Gomes, V; (...); Marques, CJ
Meeting Abstract. 2022
Common genetic variation in KATNAL1 non-coding regions is involved in the susceptibility to severe phenotypes of male infertility
Cervan Martin, M; (...); Carmona, FD
Article. 10.1111/andr.13221. 2022
Common Variation in the PIN1 Locus Increases the Genetic Risk to Suffer from Sertoli Cell-Only Syndrome
Cervan Martin, M; (...); Palomino Morales, RJ
Article. 10.3390/jpm12060932. 2022
Contribution of TEX15 genetic variants to the risk of developing severe non-obstructive oligozoospermia
Guzm?n Jim?nez, A; (...); Lisbon, CG
Article. 10.3389/fcell.2022.1089782. 2022
Chemobrain: mitoxantrone-induced oxidative stress, apoptotic and autophagic neuronal death in adult CD-1 mice
Dias Carvalho, A; (...); Costa, VM
Article. 10.1007/s00204-022-03261-x. 2022
Differences in hormonal levels between heterozygous CYP21A2 pathogenic variant carriers, non-carriers, and females with non-classic congenital hyperplasia
Afonso, A.; (...); Fontoura, M
Article. 10.20945/2359-3997000000437. 2022
Diverse monogenic subforms of human spermatogenic failure
Nagirnaja, L; (...); Conrad, DF
Article. 10.1038/s41467-022-35661-z. 2022
Early pathways of toxicity triggered by 3,4-methylene-dioxypyrovalerone unveiled by in vivo toxicometabolomics
Araujo, A. M.; (...); Carvalho, F.
Meeting Abstract. 2021
ESHRE PGT Consortium data collection XXI: PGT analyses in 2018†
Spinella, F; (...); Van Montfoort, A
Article. 10.1093/hropen/hoad010. 2023
Synthetic Cannabinoids and senescence markersi n vitro: impact on cell proliferation, influence of cannabinoid receptors, and beta-galactosidase activity in SH-SY5Y cells
Roque-Bravo, R.; (...); Dias-da-Silva, D.
Meeting Abstract. 2023
The Complexity of Decisions in Genetics: Annotation of Three Novel Variants in the PKD1 and PKD2 Genes
Barata, R; (...); Oliveira, JP
Article. 10.1159/000534969. 2024
The influence of selected synthetic cannabinoids on in vitro proliferation and viability of neuronal cell models
Bravo, R. Roque; (...); Da Silva, D. Dias
Meeting Abstract. 10.1016/j.toxlet.2022.07.163. 2022
The influence of the anticancer drugs doxorubicin and mitoxantrone on cardiac metabolism and autophagy
Brandao, S. R.; (...); Costa, V. M.
Meeting Abstract. 2021
The synthetic cannabinoid ADB-FUBINACA modulates mitochondrial activity and dynamics during neurodifferentiation of NG108-15 cells
Malheiro, R. F.; (...); Silva, J. P.
Meeting Abstract. 10.1016/j.toxlet.2022.07.600. 2022
The synthetic cannabinoid THJ-2201 increases the differentiation of primary hippocampal neurons and early astrocyte activation but decreases neuronal maturation
Silva, R.; (...); Silva, J. P.
Meeting Abstract. 10.1016/j.toxlet.2022.07.602. 2022
The Synthetic Sannabinoid ADB-FUBINACA decreases global DNA methylation during the neuronal differentiation of NG108-15 cells by increasing TET activity
Pereira-Teixeira, C.; (...); Silva, J. P.
Meeting Abstract. 2023
Varenicline increases histone H3 acetylation, while affecting global DNA methylation on differentiated SH-SY5Y neuroblastoma cells
Marques, S. I.; (...); Silva, J. P.
Meeting Abstract. 2021
