Portal de investigação
The contribution of sleep to social inequalities in cardiovascular disorders: a multi-cohort study
Data de publicação:
Autores da FMUP
Participantes de fora da FMUP
- Petrovic, D
- Haba-Rubio, J
- Vargas, CD
- Kelly-Irving, M
- Vineis, P
- Kivimäki, M
- Nyberg, S
- Gandini, M
- Bochud, M
- Vollenweider, P
- d'Errico, A
- Goldberg, M
- Zins, M
- Steptoe, A
- Delpierre, C
- Heinzer, R
- Carmeli, C
- Chadeau-Hyam, M
- Stringhini, S
- Lifepath Consortium
Unidades de investigação
Abstract
Aims Sleep disturbances exhibit a strong social patterning, and inadequate sleep has been associated with adverse health outcomes, including cardiovascular disorders (CVD). However, the contribution of sleep to socioeconomic inequalities in CVD is unclear. This study pools data from eight European cohorts to investigate the role of sleep duration in the association between life-course socioeconomic status (SES) and CVD. Methods and results We used cross-sectional data from eight European cohorts, totalling 111 205 participants. Life-course SES was assessed using father's and adult occupational position. Self-reported sleep duration was categorized into recommended (6-8.5 h/night), long (>8.5h/night), and short (<6h/night). We examined two cardiovascular outcomes: coronary heart disease (CHD) and stroke. Main analyses were conducted using pooled data and examined the association between life-course SES and CVD, and the contribution of sleep duration to this gradient using counterfactual mediation. Low father's occupational position was associated with an increased risk of CHD (men: OR=1.19, 95% CI [1.04; 1.37]; women: OR=1.25, 95% CI [1.02; 1.54]), with marginal decrease of the gradient after accounting for adult occupational position (men: OR=1.17, 95% CI [1.02; 1.35]; women: OR=1.22, 95% CI [0.99; 1.52]), and no mediating effect by short sleep duration. Low adult occupational position was associated with an increased risk of CHD in both men and women (men: OR=1.48, 95% CI [1.14; 1.92]; women: OR=1.53, 95% CI [1.04; 2.21]). Short sleep duration meaningfully contributed to the association between adult occupational position and CHD in men, with 13.4% mediation. Stroke did not exhibit a social patterning with any of the variables examined. Conclusion This study suggests that inadequate sleep accounts to a meaningful proportion of the association between adult occupational position and CHD, at least in men. With sleep increasingly being considered an important cardiovascular risk factor in its own terms, our study additionally points to its potential role in social inequalities in cardiovascular disease.
Dados da publicação
- ISSN/ISSNe:
- 1755-3245, 0008-6363
- Tipo:
- Article
- Páginas:
- 1514-1524
- DOI:
- 10.1093/cvr/cvz267
Cardiovascular Research Oxford University Press
Citações Recebidas na Web of Science: 11
Documentos
- Não há documentos
Filiações
Keywords
- Socioeconomic status; Life-course; Sleep duration; Mediation; Cardiovascular disorders
Financiamento
Proyectos asociados
Estudo dos factores de risco cardiovascular numa população adulta da Província do Bengo, Angola
Investigador Principal: José Henrique Dias Pinto de Barros
Estudo Clínico Académico . 2019
Citar a publicação
Petrovic D,Haba J,Vargas CD,Kelly M,Vineis P,Kivimäki M,Nyberg S,Gandini M,Bochud M,Vollenweider P,d'Errico A,Barros H,Fraga S,Goldberg M,Zins M,Steptoe A,Delpierre C,Heinzer R,Carmeli C,Chadeau M,Stringhini S,Lifepath C. The contribution of sleep to social inequalities in cardiovascular disorders: a multi-cohort study. Cardiovasc. Res. 2020. 116. (8):p. 1514-1524. IF:10,787. (1).
