Incidence Trends of Inflammatory Bowel Disease in a Southern European Country: A Mirror of the Western World?

Data de publicação:

Autores da FMUP

  • Claudia Camila Rodrigues Pereira Dias

    Autor

  • Fernando José Magro Dias

    Autor

Participantes de fora da FMUP

  • Santiago, M
  • Stocker, F
  • Ministro, P
  • Gonçalves, R
  • Carvalho, D
  • Portela, F
  • Correia, L
  • Lago, P
  • Trindade, E

Unidades de investigação

Abstract

INTRODUCTION: Inflammatory bowel disease (IBD) affects people from all age categories worldwide. Although the incidence of the disease is stabilizing or decreasing in most Western world countries, its prevalence is still increasing because of the rise in life expectancy and better disease management. This work intends to identify the trends related to IBD incidence nationwide, analyzing regional, sex, and age distributions. METHODS: Data were provided by the Portuguese Shared Services of the Ministry of Health. This study consisted of a retrospective analysis of all first consultations coded for "Chronic enteritis/ulcerative colitis" (D94) in a primary healthcare setting, between 2017 and 2020, in Portugal. The primary outcome measure was the IBD incidence rate per 100,000 inhabitants. We also calculated the incidence rate per person-year and forecasted incidence until 2024. RESULTS: Between 2017 and 2019, the incidence rate of IBD in Portugal decreased from 54.9 to 48.6 per 100,000 inhabitants. The average incidence was 20 new cases of IBD per 1,000 person-year. It was predicted that, in December 2023, IBD incidence would reach 305.4 new cases (95% Prediction Interval 156.6-454.3), a similar result to the values forecasted for December 2021 (305.4, 95% Prediction Interval 197.3-413.6). DISCUSSION: The incidence of IBD slightly declined from 2017 to 2019, and it is posed to stabilize in the future. The presented data are of the utmost importance for the characterization of IBD in Southern European countries and the establishment of future health policies in the setting of compounding prevalence in the Western world.

Dados da publicação

ISSN/ISSNe:
2155-384X, 2155-384X

Clinical and Translational Gastroenterology  Nature Publishing Group

Tipo:
Article
Páginas:
481-
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 5

Citações Recebidas na Scopus: 9

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Keywords

  • Chronic Disease; Colitis, Ulcerative; Crohn Disease; Humans; Incidence; Inflammatory Bowel Diseases; Retrospective Studies; Western World; chronic disease; Crohn disease; human; incidence; inflammatory bowel disease; retrospective study; ulcerative colitis; Western world

Financiamento

Proyectos asociados

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Iron deficiency and inflammatory bowel disease. Correlation with inflammation and Vitamin D status.

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Estudo Observacional Académico (IronIBD) . 2021

Looking 4WARD: The role of dipeptidyl peptidase 4 (DPP-4) in inflammatory bowel disease (IBD) as a novel biomarker for predicting disease activity and monitoring response to therapy in IBD patients.

Investigador Principal: Fernando José Magro Dias

Estudo Observacional Académico (4WARD) . 2021

Isolated Ulceration of Crohn’s Anastomosis

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Estudo Clínico Académico . 2021

Therapeutic Drug Monitoring: An Emergent Approach in Inflammatory Bowel Disease

Investigador Principal: Fernando José Magro Dias

Estudo Clínico Académico . 2021

Contributo da endoscopia, biomarcadores e imagiologia na evolução clinica dos doentes com doença inflamatória intestinal

Investigador Principal: Fernando José Magro Dias

Estudo Clínico Académico . 2019

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