Portal de investigação
High Prevalence of Human Papillomavirus on Anal and Oral Samples from Men and Women with External Anogenital Warts: The HERCOLES Study
Data de publicação:
Autores da FMUP
Participantes de fora da FMUP
- Santo, I
- Azevedo, J
- Pista, A
- Dias, C
- Cunha, MJ
- Azevedo, J
- Santo, I
- Marcelino, M
- Reis, JP
- Portelinha, AR
- Cabral, AR
- Coutinho, MI
- Gouveia, M
- Teixeira, VB
- Brito, C
- Fernandes, JC
- Resende, C
- Ferreira, O
- Fernandes, C
- Laureano, A
- Fernandes, PV
- Mestre, T
- Bártolo, E
- Matos, D
- Barreiros, H
- Alves, J
- Coelho, R
- Lisboa, C
- Moreira, C
- Borges-Costa, J
- Gouveia, AI
- Lopes, L
- Uva, L
- Azevedo, L
- Cirnes, L
- Faustino, A
- Santos, S
- HERCOLES Study Grp
Unidades de investigação
Abstract
Human papillomavirus (HPV) infection is highly prevalent in the sexually active population. This study estimates the prevalence of HPV DNA in anal and oral samples from a cohort of men and women with incident anogenital warts. Anal and/ or oral samples from 541 patients with anogenital warts were tested for 35 HPV genotypes using a PCR assay. The overall prevalence of anal HPV and oral HPV DNA was 59.9% (n = 305/ 509; 95% confidence interval (CI) 55.664.1%) and 14.5% (n = 78/ 538; 95% CI 11.8-17.7%), respectively. Among patients with perianal warts, the anal HPV DNA prevalence was 92.3% (95% CI 87.095.5%). Anal HPV DNA prevalence in patients with genital warts but no perianal warts was 55.7% (95% CI 50.6-60.7%). Both anal and oral HPV infections were more common in men who have sex with men than in heterosexual men (90.4% versus 38.5% and 20.8% versus 11.8%, respectively). Anal high risk-HPV infection was more common in women (58.8%) and in men who have sex with men (67.7%). We found that anogenital warts represent a clinical marker for both anal and oral HPV infections, including anal high risk-HPV infections, particularly among women and men who have sex with men.
Dados da publicação
- ISSN/ISSNe:
- 1651-2057, 0001-5555
- Tipo:
- Article
- Páginas:
- 557-563
- Link para outro recurso:
- www.scopus.com
Acta Dermato-Venereologica Medical Journals/Acta D-V
Citações Recebidas na Web of Science: 7
Citações Recebidas na Scopus: 8
Documentos
- Não há documentos
Filiações
Keywords
- HPV; anal canal; oral mucosa; anogenital warts; epidemiology.
Financiamento
Proyectos asociados
Registo global de insuficiência cardíaca congestiva.
Investigador Principal: José Carlos de Magalhães Silva Cardoso
Estudo Observacional Académico (IC_Congestiva) . 2019
Citar a publicação
Lisboa C,I,Azevedo J,Azevedo L,Pista A,Dias C,Cunha MJ,Azevedo J,I,Marcelino M,Reis JP,Portelinha AR,Cabral AR,Coutinho MI,Gouveia M,Teixeira VB,Brito C,Fernandes JC,Araújo C,Resende C,Ferreira O,Cardoso J,Fernandes C,Rodrigues A,Laureano A,Fernandes PV,Mestre T,Bártolo E,Matos D,Barreiros H,Alves J,Coelho R,Lisboa C,Moreira C,Borges J,Gouveia AI,Teixeira A,Lopes L,Uva L,Azevedo L,Dias CC,Machado JC,Cirnes L,Faustino A,Santos S,HERCOLES GRP. High Prevalence of Human Papillomavirus on Anal and Oral Samples from Men and Women with External Anogenital Warts: The HERCOLES Study. Acta Derm.-Venereol. 2019. 99. (6):p. 557-563. IF:4,016. (1).
