ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation

Autores da FMUP
Participantes de fora da FMUP
- Buse, GL
- Pinto, BB
- Abbott, TEF
- Ackland, G
- Afshari, A
- De Hert, S
- Fellahi, JL
- Giossi, L
- Kavsak, P
- Longrois, D
- M'Pembele, R
- Nucaro, A
- Popova, E
- Puelacher, C
- Richards, T
- Roth, S
- Sheka, M
- Szczeklik, W
- van Waes, J
- Walder, B
- Chew, MS
Unidades de investigação
Abstract
BACKGROUNDIn recent years, there has been increasing focus on the use of cardiac biomarkers in patients undergoing noncardiac surgery.AIMSThe aim of this focused guideline was to provide updated guidance regarding the pre-, post- and combined pre-and postoperative use of cardiac troponin and B-type natriuretic peptides in adult patients undergoing noncardiac surgery.METHODSThe guidelines were prepared using Grading of Recommendations Assessment Development and Evaluation (GRADE) methodology. This included the definition of critical outcomes, a systematic literature search, appraisal of certainty of evidence, evaluation of biomarker measurement in terms of the balance of desirable and undesirable effects including clinical outcomes, resource use, health inequality, stakeholder acceptance, and implementation. The panel differentiated between three different scopes of applications: cardiac biomarkers as prognostic factors, as tools for risk prediction, and for biomarker-enhanced management strategies.RESULTSIn a modified Delphi process, the task force defined 12 critical outcomes. The systematic literature search resulted in over 25,000 hits, of which 115 full-text articles formed the body of evidence for recommendations. The evidence appraisal indicated heterogeneity in the certainty of evidence across critical outcomes. Further, there was relevant gradient in the certainty of evidence across the three scopes of application. Recommendations were issued and if this was not possible due to limited evidence, clinical practice statements were produced.CONCLUSIONThe ESAIC focused guidelines provide guidance on the perioperative use of cardiac troponin and B-type natriuretic peptides in patients undergoing noncardiac surgery, for three different scopes of application.
Dados da publicação
- ISSN/ISSNe:
- 0265-0215, 1365-2346
- Tipo:
- Article
- Páginas:
- 888-927
- Link para outro recurso:
- www.scopus.com
European Journal of Anaesthesiology Lippincott Williams and Wilkins
Citações Recebidas na Web of Science: 7
Citações Recebidas na Scopus: 27
Documentos
- Não há documentos
Filiações
Keywords
- BRAIN NATRIURETIC PEPTIDE; ADVERSE CARDIOVASCULAR EVENTS; VASCULAR-SURGERY PATIENTS; SENSITIVITY TROPONIN-T; LONG-TERM MORTALITY; POSTOPERATIVE ATRIAL-FIBRILLATION; ABDOMINAL AORTIC-ANEURYSM; MAJOR NONCARDIAC SURGERY; C-REACTIVE PROTEIN; MYOCARDIAL INJURY
Financiamento
Proyectos asociados
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Investigador Principal: Fernando José Pereira Alves Abelha
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Prediction models for adverse outcomes in vascular surgery
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Citar a publicação
Buse GL,Pinto BB,Abelha F,Abbott T,Ackland G,Afshari A,De Hert S,Fellahi JL,Giossi L,Kavsak P,Longrois D,M'Pembele R,Nucaro A,Popova E,Puelacher C,Richards T,Roth S,Sheka M,Szczeklik W,van J,Walder B,Chew MS. ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation. Eur. J. Anaesth. 2023. 40. (12):p. 888-927. IF:3,600. (2).