Cost-effectiveness analysis of grass pollen specific immunotherapy in children with allergic rhinitis compared to the standard of care symptomatic treatment in Portugal

Autores da FMUP
Participantes de fora da FMUP
- Farraia, M
- Paci?ncia, I
- Mendes, FC
- Rufo, JC
Unidades de investigação
Abstract
Background. Cost-effectiveness studies evaluating allergen immunothera-py (AIT) in children are scarce. We aim to compare the cost-effectiveness of subcutaneous (SCIT) and sublingual immunotherapy (SLIT) against stan-dard-of-care (SOC) treatment in children with grass pollen allergic rhinitis. Methods. We created a Markov model to compare the three strategies over a 10-year horizon. SOC was the reference to calculate the incremental cost-ef-fectiveness ratio (ICER). Deterministic and probabilistic sensitivity analysis were used to assess models' uncertainty. Results. We obtained an ICER of 12,605euro and 6,318euro for SLIT and SCIT, respectively. In sensitivity analysis, SCIT was more cost-effective than SLIT. Conclusions. AIT is cost-effective in children with grass pollen allergic rhinitis, especially for the subcutaneous route.
Dados da publicação
- ISSN/ISSNe:
- 1764-1489,
- Tipo:
- Article
- Páginas:
- 212-228
- Link para outro recurso:
- www.scopus.com
European Annals of Allergy and Clinical Immunology EDRA S.p.A
Citações Recebidas na Web of Science: 1
Citações Recebidas na Scopus: 2
Documentos
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Filiações
Keywords
- Allergen immunotherapy; allergic rhinitis; children; cost-effectiveness; grass pollen
Financiamento
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Citar a publicação
Farraia M,Paci?ncia I,Mendes FC,Rufo JC,Delgado L,Moreira A. Cost-effectiveness analysis of grass pollen specific immunotherapy in children with allergic rhinitis compared to the standard of care symptomatic treatment in Portugal. Eur. Ann. Allergy Clinical Immunol. 2023. 55. (5):p. 212-228.