Portal de investigação
Narrow Band Imaging versus White Light for the Detection of Sessile Serrated Colorectal Lesions: A Randomized Clinical Trial
Data de publicação:
Data Ahead of Print:
Autores da FMUP
Participantes de fora da FMUP
- Ferreira, AO
- Reves, JB
- Nascimento, C
- Frias Gomes, C
- Costa Santos, MP
- Ramos, LR
- Palmela, C
- Gloria, L
- Cravo, M
- Canena, J
Unidades de investigação
Abstract
Background: Colorectal cancer (CRC) is a leading cause of cancer. The detection of pre-malignant lesions by colonoscopy is associated with reduced CRC incidence and mortality. Narrow band imaging has shown promising but conflicting results for the detection of serrated lesions. Methods: We performed a randomized clinical trial to compare the mean detection of serrated lesions and hyperplastic polyps >= 10 mm with NBI or high-definition white light (HD-WL) withdrawal. We also compared all sessile serrated lesions (SSLs), adenoma, and polyp prevalence and rates. Results: Overall, 782 patients were randomized (WL group 392 patients; NBI group 390 patients). The average number of serrated lesions and hyperplastic polyps >= 10 mm detected per colonoscopy (primary endpoint) was similar between the HD-WL and NBI group (0.118 vs. 0.156, p = 0.44). Likewise, the adenoma detection rate (55.2% vs. 53.2%, p = 0.58) and SSL detection rate (6.8% vs. 7.5%, p = 0.502) were not different between the two study groups. Withdrawal time was higher in the NBI group (10.88 vs. 9.47 min, p = 0.004), with a statistically nonsignificant higher total procedure time (20.97 vs. 19.30 min, p = 0.052). Conclusions: The routine utilization of narrow band imaging does not improve the detection of serrated class lesions or any pre-malignant lesion and increases the withdrawal time.
Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel.
Dados da publicação
- ISSN/ISSNe:
- 2341-4545, 2387-1954
- Tipo:
- Article
- Páginas:
- 368-374
- DOI:
- 10.1159/000526606
- Link para outro recurso:
- www.scopus.com
GE Portuguese Journal of Gastroenterology Karger AG
Citações Recebidas na Scopus: 1
Documentos
- Não há documentos
Filiações
Keywords
- Colonoscopy; Quality; Sessile serrated lesion; Adenoma; Narrow band imaging; Chromoendoscopy
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Citar a publicação
Ferreira AO,Reves JB,Nascimento C,Frias C,Costa MP,Ramos LR,Palmela C,Gloria L,Cravo M,Dinis M,Canena J. Narrow Band Imaging versus White Light for the Detection of Sessile Serrated Colorectal Lesions: A Randomized Clinical Trial. GE Port. J. Gastroenterol. 2023. 30. (5):p. 368-374.
