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The SARS-CoV-2 Infection Among Students in the University of Porto: A Cross-Sectional Study

Data de publicação:

Autores da FMUP

  • José Henrique Dias Pinto De Barros

    Autor

Participantes de fora da FMUP

  • Meireles, P
  • Costa, JP
  • Novais, MJ
  • Miranda, D
  • Lopes, MM
  • Severo, M.

Unidades de investigação

Abstract

Objective: We aimed to quantify SARS-CoV-2 specific antibodies' seroprevalence among university students in Porto.Methods: A rapid point of care testing for SARS-CoV-2 specific immunoglobulin (Ig) M and IgG antibodies was performed, and a questionnaire was applied to 6512 voluntary students from September to December 2020. We computed the apparent IgM, IgG, and IgM or IgG prevalence, and the true prevalence and 95% credible intervals (95% CI) using Bayesian inference.Results: We found an apparent prevalence (IgM or IgG) of 9.7%, the true prevalence being 7.9% (95% CI 4.9-11.1). Prevalence was significantly higher among males (10.9% vs. 9.2%), international students (18.1% vs. 10.4% local vs. 8.8% nationally displaced), and increased with age. Those with a known risk contact, that experienced quarantine, had symptoms, or a previous negative molecular test had a higher seroprevalence. Of the 91 (1.4%) students who reported a molecular diagnosis, 86.8% were reactive for IgM or IgG.Conclusion: Based on immunological evidence infection was 5.6-fold the reported molecular diagnosis. The higher seroprevalence among male, older, and international students emphasizes the importance of identifying particular groups.

Dados da publicação

ISSN/ISSNe:
1661-8564, 1661-8556

International Journal of Public Health  Frontiers Media S.A.

Tipo:
Article
Páginas:
-

Citações Recebidas na Web of Science: 2

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Keywords

  • seroprevalence; university students; SARS-CoV-2; antibodies; seroepidemiology

Campos de estudo

Financiamento

Fundo Social Europeu (DFA/BD/8562/2020)
Laboratory for Integrative and Translational Research in Population Health
national funds of Fundacao para a Ciencia e Tecnologia
Research Unit of Epidemiology-Institute of Public Health of the University of Porto (LA/P/0064/2020)
Research Unit of Epidemiology-Institute of Public Health of the University of Porto (UIDB/04750/2020)
University of Porto

Proyectos asociados

Efetividade do Controlo da Schistosomíase e Comorbilidades no Bengo, Angola.

Investigador Principal: José Henrique Dias Pinto de Barros

Estudo Clínico Académico . 2022

Cuidados Prénatais e sua Influência nos Resultados da Gravidez e do Parto, Luanda-Angola.

Investigador Principal: José Henrique Dias Pinto de Barros

Estudo Clínico Académico . 2022

Breast milk feeding practices among very preterm infants: effects on health-related outcomes during childhood.

Investigador Principal: José Henrique Dias Pinto de Barros

Estudo Clínico Académico . 2022

Data from a Health and Demographic Surveillance System and a Verbal Autopsy System in Dande, Angola

Investigador Principal: José Henrique Dias Pinto de Barros

Estudo Clínico Académico . 2022

Preexposure prophylaxis for HIV prevention among men who have sex with men: understanding eligibility and early uptake

Investigador Principal: José Henrique Dias Pinto de Barros

Estudo Clínico Académico . 2021

Eficácia de intervenções educacionais comunitárias em nutrição e WASH (Water, Sanitation and Hygiene) / Malária na diminuição da prevalência de anemia e malnutrição em crianças menores de 5 anos

Investigador Principal: José Henrique Dias Pinto de Barros

Estudo Clínico Académico . 2021

Estudo dos factores de risco cardiovascular numa população adulta da Província do Bengo, Angola

Investigador Principal: José Henrique Dias Pinto de Barros

Estudo Clínico Académico . 2019

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