Liquid biopsy: the value of different bodily fluids

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • Maria Gabriela Oliveira Fernandes

    Autor

  • Venceslau José Coelho Pinto Hespanhol

    Autor

Participantes de fora da FMUP

  • Santos, V
  • Freitas, C
  • Sousa, C
  • Reboredo, C
  • Cruz-Martins, N
  • Mosquera, J
  • Campelo, R

Unidades de investigação

Abstract

Liquid biopsies have gained an increasing interest in the last years among medical and scientific communities. Indeed, the value of liquid effusions, while less invasive and more accurate techniques, has been markedly highlighted. Peripheral blood comprises the most often analyzed sample, but recent evidences have pointed out the huge importance of other bodily fluids, including pleural and peritoneal fluids, urine, saliva and cerebrospinal fluid in the detection and monitoring of different tumor types. In face to these advances, this review aims to provide an overview of the value of tumor-associated mutations, detectable in different effusions, and how they can be used in clinical practice, namely in prognosis assessment and early disease and minimal disease recurrence detection, and in predicting the treatment response or acquired-resistance development.

Dados da publicação

ISSN/ISSNe:
1752-0363, 1752-0371

Biomarkers in Medicine  Future Medicine Ltd.

Tipo:
Review
Páginas:
127-145
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 9

Citações Recebidas na Scopus: 14

Documentos

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Métricas

Filiações mostrar / ocultar

Keywords

  • bodily fluids; cancer biomarkers; cancer monitoring; liquid biopsy; tumors

Proyectos asociados

Doença do Refluxo Gastro-esofágico e Doença Pulmonar

Investigador Principal: Venceslau José Coelho Pinto Hespanhol

Estudo Clínico Académico (Refluxo Gastro-esofágic) . 2020

A importância do diagnóstico na Fibrose Pulmonar Idiopática

Investigador Principal: Venceslau José Coelho Pinto Hespanhol

Estudo Clínico Académico (FPI) . 2020

Imunoterapia no cancro do pulmão: PD-L1, biomarcador preditivo?

Investigador Principal: Venceslau José Coelho Pinto Hespanhol

Estudo Clínico Académico . 2020

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