Portal de investigação
Diagnosis of MALT Lymphoma from Surveillance Endoscopy of a Patient with a CDH1 Gene Germline Mutation
Data de publicação:
Data Ahead of Print:
Autores da FMUP
Participantes de fora da FMUP
- Pinto, C
- Cunha, AL
- Rodrigues, A
- Dias, R
- Brandao, C
Unidades de investigação
Abstract
Carriers of the mutated CDH1 gene have an increased risk of developing early-onset signet-ring cell (diffuse) gastric cancer. We present a case of a young patient with a confirmed mutation of the CDH1 gene, who was diagnosed with a gastric marginal zone B-cell lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT lymphoma) from surveillance endoscopy. He underwent Helicobacter pylori eradication treatment and was subsequently submitted to a total prophylactic gastrectomy. The surgical specimen only revealed foci of signet-ring cell carcinoma (SRCC) in situ without lymphoma signs. We highlight here the occurrence of other pathology in high-risk patients as well as its possible influence on the decision to perform gastrectomy.
Copyright © 2021 by S. Karger AG, Basel.
Dados da publicação
- ISSN/ISSNe:
- 2341-4545, 2387-1954
- Tipo:
- Article
- Páginas:
- 51-55
- DOI:
- 10.1159/000514652
- Link para outro recurso:
- www.scopus.com
GE Portuguese Journal of Gastroenterology Karger AG
Citações Recebidas na Web of Science: 1
Citações Recebidas na Scopus: 1
Documentos
- Não há documentos
Filiações
Keywords
- CDH1 protein; Stomach neoplasms; Helicobacter pylori; Marginal zone B-cell lymphoma
Proyectos asociados
Effectiveness of endoscopic resection of colonic lesions > 20mm
Investigador Principal: Mário Jorge Dinis Ribeiro
Estudo Clínico Académico (Colonic lesions) . 2020
Citar a publicação
Pinto C,Cunha AL,Rodrigues A,Dias R,Brandao C,Dinis M. Diagnosis of MALT Lymphoma from Surveillance Endoscopy of a Patient with a <i>CDH1</i> Gene Germline Mutation. GE Port. J. Gastroenterol. 2022. 29. (1):p. 51-55.
