Portal de investigação
Disease Clearance as a New Outcome in Ulcerative Colitis: a Systematic Review and Expert Consensus
Autores da FMUP
Participantes de fora da FMUP
- D'Amico, F
- Siegmund, B
- Kobayashi, T
- Kotze, PG
- Solitano, V
- Caron, B
- Al Awadhi, S
- Hart, A
- Jairath, V
- Dignass, A
- Peyrin-Biroulet, L
- Danese, S
- End Point Cluster Int Org Study In
Unidades de investigação
Abstract
The concept of disease clearance has been proposed as a potential target in ulcerative colitis (UC). We conducted a systematic review to investigate the role of disease clearance, defined as a composite outcome including simultaneous clinical, endoscopic, and histologic remission of disease in the management of patients with UC. Based on the literature data, statements regarding disease clearance were developed and voted on by the members of the International Organization for the Study of Inflammatory Bowel Diseases (IOIBD) according to a Delphi methodology. A definition of disease clearance was proposed to standardize its use in clinical practice and clinical trials and to provide practical recommendations for its implementation as a therapeutic target in UC.
Dados da publicação
- ISSN/ISSNe:
- 1078-0998, 1536-4844
- Tipo:
- Review
- Páginas:
- 1009-1017
- DOI:
- 10.1093/ibd/izad159
- Link para outro recurso:
- www.scopus.com
Inflammatory Bowel Diseases Oxford University Press
Citações Recebidas na Web of Science: 2
Citações Recebidas na Scopus: 8
Documentos
- Não há documentos
Filiações
Keywords
- ulcerative colitis; inflammatory bowel disease; disease clearance; deep remission
Proyectos asociados
Gut microbiome and IBD therapy: an interplay?
Investigador Principal: Fernando José Magro Dias
Estudo Observacional Académico (GutIBD) . 2021
Iron deficiency and inflammatory bowel disease. Correlation with inflammation and Vitamin D status.
Investigador Principal: Fernando José Magro Dias
Estudo Observacional Académico (IronIBD) . 2021
Looking 4WARD: The role of dipeptidyl peptidase 4 (DPP-4) in inflammatory bowel disease (IBD) as a novel biomarker for predicting disease activity and monitoring response to therapy in IBD patients.
Investigador Principal: Fernando José Magro Dias
Estudo Observacional Académico (4WARD) . 2021
Isolated Ulceration of Crohn’s Anastomosis
Investigador Principal: Fernando José Magro Dias
Estudo Clínico Académico . 2021
Histologic Features of Colon Biopsies (Geboes Score) Associated With Progression of Ulcerative Colitis for the First 36 Months After Biopsy
Investigador Principal: Fernando José Magro Dias
Estudo Clínico Académico . 2022
Therapeutic Drug Monitoring: An Emergent Approach in Inflammatory Bowel Disease
Investigador Principal: Fernando José Magro Dias
Estudo Clínico Académico . 2021
Contributo da endoscopia, biomarcadores e imagiologia na evolução clinica dos doentes com doença inflamatória intestinal
Investigador Principal: Fernando José Magro Dias
Estudo Clínico Académico . 2019
Citar a publicação
D'Amico F,Magro F,Siegmund B,Kobayashi T,Kotze PG,Solitano V,Caron B,Al Awadhi S,Hart A,Jairath V,Dignass A,Peyrin L,Danese S,End Point Cluster Int Org Study IN. Disease Clearance as a New Outcome in Ulcerative Colitis: a Systematic Review and Expert Consensus. Inflammatory Bowel Dis. 2023. 30(6):p. 1009-1017. IF:4,900. (2).
