Screening, Diagnosis and Management of Atrial Fibrillation in Cancer Patients: Current Evidence and Future Perspectives

Data de publicação: 01/01/2022

Autores da FMUP

• Joaquim Adelino Correia Ferreira Leite Moreira

  Autor

• Ricardo Manuel Alves Monteiro Fontes De Carvalho

  Autor

Participantes de fora da FMUP

• Goncalves Teixeira, P
• Costa, T
• Fragoso, I
• Ferreira, D.
• Brandao, M
• Sampaio, F.
• Ribeiro, J

Unidades de investigação

• Cirurgia e Fisiologia

• Laboratório Associado RISE- Rede de Investigação em Saúde

  

  Investigador

  Fernando Carlos De Landér Schmitt

• RISE-Health

  

  Investigador

  Fernando Carlos De Landér Schmitt

Abstract

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in the general population, carrying a high morbimortality burden, and this also holds true in cancer patients. The association between AF and cancer goes even further, with some studies suggesting that AF can be a marker of occult cancer. There is, however, a remarkable paucity of data concerning specific challenges of AF management in cancer patients. AF prompt recognition and management in this special population can lessen the arrhythmia-related morbidity and have an important prognostic benefit. This review will focus on current AF diagnosis and management challenges in cancer patients, with special emphasis on AF screening strategies and devices, and anticoagulation therapy with non-vitamin K antagonist oral anti-coagulants (NOACs) for thromboembolic prevention in these patients. Some insights concerning future perspectives for AF prevention, diagnosis, and treatment in this special population will also be addressed.

Keywords

• Administration, Oral; Anticoagulants; Atrial Fibrillation; Early Detection of Cancer; Humans; Neoplasms; Stroke; anticoagulant agent; antivitamin K; apixaban; C reactive protein; digoxin; diltiazem; ibrutinib; immune checkpoint inhibitor; interleukin 2; interleukin 6; low molecular weight heparin; monocyte chemotactic protein 1; tumor necrosis factor; verapamil; anticoagulant agent; atrial fibrillation; blood clotting; cancer patient; cancer therapy; cardiotoxicity; electrocardiogram; electrocardiography; heart arrhythmia; heart infarction; heart muscle fibrosis; hospitalization; hypogonadism; oncology; plethysmography; Review; thrombocytopenia; thyroiditis; atrial fibrillation; cerebrovascular accident; complication; early cancer diagnosis; human; neoplasm; oral drug administration