Tea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • Nuno Miguel De Sousa Lunet

    Autor

Participantes de fora da FMUP

  • de la Hera, MG
  • Lpez Carrillo, L
  • Hernndez Ramrez, RU
  • Hamada, GS
  • Ward, MH
  • Mu, L
  • Malekzadeh, R
  • Pourfarzi, F
  • Trichopoulou, A
  • Karakatsani, A
  • Kurtz, RC
  • Lagiou, A
  • Lagiou, P
  • Boccia, S
  • Boffetta, P
  • Camargo, MC
  • Negri, E
  • La Vecchia, C
  • Martimianaki, G
  • Alicandro, G
  • Pelucchi, C
  • Bonzi, R
  • Rota, M
  • Hu, JF
  • Johnson, KC
  • Rabkin, CS
  • Liao, LM
  • Sinha, R
  • Zhang, ZF
  • Dalmartello, M
  • Morais, S.
  • Palli, D
  • Ferraroni, M
  • Yu, GP
  • Tsugane, S
  • Hidaka, A
  • Curado, MP
  • Dias Neto, E
  • Zaridze, D
  • Maximovitch, D
  • Vioque, J

Unidades de investigação

Abstract

Background Evidence from epidemiological studies on the role of tea drinking in gastric cancer risk remains inconsistent. We aimed to investigate and quantify the relationship between tea consumption and gastric cancer in the Stomach cancer Pooling (StoP) Project consortium. Methods A total of 9438 cases and 20,451 controls from 22 studies worldwide were included. Odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) of gastric cancer for regular versus non-regular tea drinkers were estimated by one and two-stage modelling analyses, including terms for sex, age and the main recognised risk factors for gastric cancer. Results Compared to non-regular drinkers, the estimated adjusted pooled OR for regular tea drinkers was 0.91 (95% CI: 0.85-0.97). When the amount of tea consumed was considered, the OR for consumption of 1-2 cups/day was 1.01 (95% CI: 0.94-1.09) and for >3 cups/day was 0.91 (95% CI: 0.80-1.03). Stronger inverse associations emerged among regular drinkers in China and Japan (OR: 0.67, 95% CI: 0.49-0.91) where green tea is consumed, in subjects with H. pylori infection (OR: 0.68, 95% CI: 0.58-0.80), and for gastric cardia cancer (OR: 0.64, 95% CI: 0.49-0.84). Conclusion Our results indicate a weak inverse association between tea consumption and gastric cancer.

Dados da publicação

ISSN/ISSNe:
1532-1827, 0007-0920

British Journal of Cancer  Nature Publishing Group

Tipo:
Article
Páginas:
726-734
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 7

Citações Recebidas na Scopus: 10

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Keywords

  • GREEN-TEA; JAPANESE BRAZILIANS; DIETARY-INTAKE; RISK-FACTORS; ASSOCIATION; ADENOCARCINOMA; METAANALYSIS; BEVERAGES; DRINKING; SUBSITE

Proyectos asociados

Healthcare use among cancer patients and their partners in different phases of the cancer pathway

Investigador Principal: Nuno Miguel de Sousa Lunet

Estudo Clínico Académico . 2021

Reshaping organized cervical cancer screening: strategies to increase the adherence and reduce invitation costs

Investigador Principal: Nuno Miguel de Sousa Lunet

Estudo Clínico Académico . 2020

Using pooled analyses based on individual participant data for a finer assessment of gastric cancer etiology

Investigador Principal: Nuno Miguel de Sousa Lunet

Estudo Clínico Académico . 2020

RISK AND SURVIVAL OF GASTRIC CANCER RELATES SECOND PRIMARY TUMOURS: A COMPETING RISKS FRAMEWORK

Investigador Principal: Nuno Miguel de Sousa Lunet

Estudo Clínico Académico . 2019

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