Suboptimal control of cardiovascular risk factors in myocardial infarction survivors in a cardiac rehabilitation program

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • Ricardo Manuel Alves Monteiro Fontes De Carvalho

    Autor

Participantes de fora da FMUP

  • Silva, V
  • Vilela, EM
  • Campos, L
  • Miranda, F
  • Torres, S
  • Joao, A
  • Teixeira, M
  • Braga, P

Unidades de investigação

Abstract

Introduction and objectives: As short-term mortality continues to decrease after myocardial infarction (MI), secondary prevention strategies attain increasing relevance. This study aimed at assessing the control of cardiovascular (CV) risk factors, including dyslipidemia, hypertension and diabetes, in a contemporary cohort of MI survivors who completed an exercise-based cardiac rehabilitation (EBCR) program. Methods: Observational, retrospective cohort study including patients admitted to a tertiary center with acute MI between November 2012 and April 2017, who completed a phase II EBCR program after discharge. Achievement of low-density lipoprotein (LD) cholesterol, blood pressure and HbA1c guideline recommended targets was assessed. Lipid profile parameters were assessed and compared at three time points (hospitalization, beginning and end of the program). Results: A total of 379 patients were included. Mean age was 58.8 +/- 10.6 years; 81% were male. Considering the European Society of Cardiologys guidelines on contemporary data collection, 61%, 87% and 71% achieved the recommended LDL cholesterol, blood pressure and HbA1c targets, respectively, at the end of the program. Combining all three risk factors, 42% achieved the recommended targets. High-sensitivity C-reactive protein decreased between the beginning and the end of the program [0.14 (0.08-0.29) mg/L to 0.12 (0.06-0.26) mg/L; p<0.001]. Conclusion: Despite contemporary management strategies, including enrollment in a structured EBCR program, a substantial number of patients presented suboptimal control of CV risk factors. Considering the dyslipidemia, hypertension and diabetes results, less than half of the enrolled individuals achieved the recommended targets. These findings highlight a pivotal unmet need which could be particularly relevant in improving CV outcomes by enhancingsecondary prevention profiles. (C) 2021 Sociedade Portuguesa de Cardiologia. Published by Elsevier Espana, S.L.U.

Dados da publicação

ISSN/ISSNe:
0870-2551, 2174-2030

Revista Portuguesa de Cardiologia  Sociedade Portuguesa De Cardiologia

Tipo:
Article
Páginas:
911-920
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 4

Citações Recebidas na Scopus: 6

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Keywords

  • Acute myocardial infarction; Secondary prevention; Dyslipidemia

Proyectos asociados

The Impact of Obesity on Cardiac Function and Morphology in Aortic Stenosis

Investigador Principal: Ricardo Manuel Alves Monteiro Fontes de Carvalho

Estudo Clínico Académico (Obesity) . 2020

Suboptimal control of cardiovascular risk factors in myocardial infarction survivors

Investigador Principal: Ricardo Manuel Alves Monteiro Fontes de Carvalho

Estudo Clínico Académico (myocard) . 2020

Cardiovascular Impact of Metabolic Syndrome: From Mechanisms to New Treatment Targets

Investigador Principal: Ricardo Manuel Alves Monteiro Fontes de Carvalho

Estudo Clínico Académico . 2021

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