Metabolic syndrome impact on nutritional deficiencies and metabolic status 1 year after sleeve gastrectomy
Autores da FMUP
Participantes de fora da FMUP
- Paredes, SCD
- Alves, MDF
- Pereira, MRDL
Unidades de investigação
Abstract
Background: A paucity of information is available on the comparative nutritional deficiencies considering the presence of metabolic syndrome (MetS) and nutritional changes after vertical sleeve gastrectomy (SG). Objectives: To compare the nutritional status in patients with and without MetS before and 1 year after SG and to investigate its association with metabolic status. Setting: A tertiary referral center. Methods: Retrospective study, including all patients submitted to SG between January 2011 and July 2015. Patients were evaluated before and 12 months after surgery. MetS presence was classified using the International Diabetes Federation/American Heart Association/National Heart, Lung, and Blood Institute 2009 definition. Univariate and multivariate analyses were applied to find associations be-tween MetS, nutritional, anthropometric, and metabolic parameters. Results: A total of 330 patients were included and MetS was present in 47%. Preoperatively, patients without MetS presented a higher percentage of folate deficiency (12% versus 2%, P < .001). Follow-up data were available for 202 patients. In the 1-year evaluation, MetS patients presented significantly lower body mass index and percent excess weight loss (70.96 +/- 20.4 versus 79.55 +/- 23.0, P < .001). These patients also presented lower homocysteine (11.76 +/- 4.3 versus 13.66 +/- 7.6, P = .027) and magnesium (19.41 +/- 2.1 versus 20.22 +/- 1.9, P = .004) levels but higher calcium (9.27 +/- .3 versus 9.16 +/- .4, P = .031) and vitamin B12 (396, P 312-504.5 versus 329, P 255-433, P = .002) levels comparing with those without MetS. Multiple linear regression evidenced that higher preoperative albumin and postoperative ferritin and homocysteine were predictors of a lower body mass index after surgery, and higher postoperative folate levels were associated with lower insulin-resistance. Conclusions: The impact of SG on nutritional parameters is affected by MetS. If not treated, preoperative deficiencies can impair postoperative metabolic status and weight loss. MetS should be considered when evaluating bariatric surgery candidates, and preoperative supplementation and long-term nutritional follow-up are required to prevent further nutritional deficiencies. (C) 2020 Published by Elsevier Inc. on behalf of American Society for Bariatric Surgery.
Dados da publicação
- ISSN/ISSNe:
- 1550-7289, 1878-7533
- Tipo:
- Article
- Páginas:
- 844-851
Surgery for Obesity and Related Diseases Elsevier Inc.
Citações Recebidas na Web of Science: 4
Documentos
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Filiações
Keywords
- Metabolic syndrome; Insulin resistance; Bariatric surgery; Sleeve gastrectomy; Nutritional status; Micronutrient status
Proyectos asociados
Ensino-aprendizagem e perfil psicológico dos estudantes de medicina na pandemia Covid-19.
Investigador Principal: Laura Virginia Pereira Teixeira Ribeiro
Estudo Observacional Académico (PerfilPsic) . 2020
Citar a publicação
Paredes SCD,Alves MDF,Pereira MRDL,Ribeiro LVPT. Metabolic syndrome impact on nutritional deficiencies and metabolic status 1 year after sleeve gastrectomy. Surg. Obes. Relat. Dis. 2020. 16. (7):p. 844-851. IF:4,734. (1).