Orbital Apex Syndrome due to Orbital Mucormycosis after Teeth Infection: A Successful Case Report

Autores da FMUP

• Ricardo Manuel De Pinto Vaz

  Autor

• António Carlos Megre Eugénio Sarmento

  Autor

• Fernando Manuel Mendes Falcão Reis

  Autor

Participantes de fora da FMUP

• Godinho, G
• Abreu, I
• Alves, G
• Leal, V
• Carvalho, AC

Unidades de investigação

• Biomedicina

• Laboratório Associado RISE- Rede de Investigação em Saúde

  

  Investigador

  Fernando Carlos De Landér Schmitt

• Medicina

• RISE-Health

  

  Investigador

  Fernando Carlos De Landér Schmitt

Abstract

Rhino-orbital-cerebral mucormycosis is a severe and rapidly progressive fungal infection associated with low survival rates. Early diagnosis and proper management are mandatory. We report the case of a 20-year-old female with diabetic ketoacidosis and teeth infection, who presented with sudden orbital apex syndrome. Several surgical procedures were necessary to provide a definite histopathological diagnosis of the fungal infection. Ultimately, given the progressive aggravation of the infection and the ineffectiveness of antifungal and antibiotic agents, an orbital exenteration was performed. A mycobacteriological examination revealed a polymicrobial culture with Mucorales. One year after the initial presentation, the patient is alive and with a good general health condition.

Keywords

• Diabetes; Exenteration; Mucorales; Mucormycosis; Teeth