Hand Transplantation-Risks and Benefits

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • Ricardo José Moreira Horta Oliveira

    Autor

Participantes de fora da FMUP

  • Lúcio, MJ

Unidades de investigação

Abstract

Composite tissue allotransplantation (CTA) is the culmination of progress in transplantation, allowing the reconstruction of the hand in amputees. Worldwide, more than 100 procedures have been performed. The aim of this work was to understand the hand allotransplantation approach, making known current aspects, risks, and benefits. A PubMed research was realized between October 2018 and March 2019, including terms like "Hand transplantation" AND "Composite tissue allotransplantation," "Hand transplantation" AND "Functional outcomes," "Hand transplantation" AND "Immunosuppression," "Hand prosthetics," "Hand Transplantation" AND "Ethics." There were included papers between 1995 and 2018, with English language, amputee human adults, systematic reviews, and clinical studies. Seventy-two papers were fully evaluated. There are technical aspects that influence the procedure like team coordination or surgical technique. It requires a long-life treatment, which has risks such as toxicity or infections. However, it allows the recovery of fine movements, and independence, to perform detailed tasks. The indications must be carefully considered, because some patients benefit from the use of prosthesis. CTA has become an option for amputees so it is important to do more research, to determine the benefits of this procedure. It is not considered a life-saving procedure, so there is an ethical debate because of the risks.

Dados da publicação

ISSN/ISSNe:
0974-3227, 0974-6897

Journal Of Hand And Microsurgery  GEORG THIEME VERLAG KG

Tipo:
Review
Páginas:
207-215
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 4

Citações Recebidas na Scopus: 7

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Keywords

  • hand allotransplantation; composite tissue allotransplantation; immunosuppression; ethics; functional outcomes; rehabilitation

Proyectos asociados

Tissue Engineering in Plastic Surgery - What Has Been Done

Investigador Principal: Ricardo José Moreira Horta Oliveira

Estudo Clínico Académico (Plastic Surgery) . 2020

Breast Implant-Associated Anaplastic Large Cell Lymphoma - the epidemiological profile in Portugal: a cross-sectional study

Investigador Principal: Ricardo José Moreira Horta Oliveira

Estudo Clínico Académico (Breast Implan) . 2020

The efficacy of combined adjuvant radiotherapy with surgical excision in the treatment of keloids.

Investigador Principal: Ricardo José Moreira Horta Oliveira

Ensaio Clínico Académico (Keloids) . 2020

A ruler for abdominoplasty preoperative markings: the potential of best scar symmetry

Investigador Principal: Ricardo José Moreira Horta Oliveira

Estudo Clínico Académico . 2020

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