Septic shock due to co-infection with Legionella pneumophila and Saprochaete clavata

Autores da FMUP

• António Carlos Megre Eugénio Sarmento

  Autor

• Maria De Lurdes Campos Dos Santos

  Autor

Participantes de fora da FMUP

• Caldas, JP
• Pinto, A.
• Faustino, AS
• Figueiredo, P

Unidades de investigação

• Medicina

Abstract

Septic shock is the most dreaded presentation of an infection, carrying a reserved prognosis. Appropriate antimicrobial therapy is therefore the mainstay of treatment, alongside organ support as needed. Legionnaires disease is mainly due to Legionella pneumophila serogroup 1 but it can be caused by other serogroups and species not detected by the urinary antigen test. Anti-tumour necrosis factor a therapy may increase the risk of invasive fungal infection, which carry a poor prognosis. We present a challenging case of a septic shock due to Legionella pneumophila and Saprochaete clavata infections, with a review of the two infections presented. (C) 2021 The Authors. Published by Elsevier Ltd.

Keywords

• cefuroxime; meropenem; piperacillin plus tazobactam; tumor necrosis factor antibody; vancomycin; adult; Article; case report; coinfection; community acquired pneumonia; computer assisted tomography; extracorporeal oxygenation; female; fever; human; human,clinical article; invasive ventilation; Legionella pneumophila; legionnaire disease; plasmapheresis; prognosis; renal replacement therapy; sensitivity and specificity; septic shock; thorax radiography