Vitamin B Complex Deficiency After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy-a Systematic Review and Meta-Analysis

Autores da FMUP

• Hugo Miguel Teixeira Ferraz Santos Sousa

  Autor

• Ana Margarida Barbosa Ribeiro Pereira

  Autor

Participantes de fora da FMUP

• Nunes R.
• Vieira S.
• Nogueiro, J.
• Bou?a-Machado R.
• Carneiro, S.
• Pinho, A.
• Lima-da-Costa E.
• Preto, J.
• group C.R.I.O.

Unidades de investigação

• Cirurgia e Fisiologia

• Medicina da Comunidade, Informação e Decisão em Saúde

Abstract

Bariatric surgery, although an effective method, still has complications, like nutritional deficiencies. Our aim was to summarize the evidence on the frequency of complex B vitamin deficiencies in studies comparing Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG). We included 25 studies for qualitative synthesis and 21 studies for quantitative synthesis. Relevant data was extracted, including proportion of patients with deficiency and mean serum vitamin values in 3 different timeframes. B12 and folate were the most prevalent deficiencies. B12 deficiency was more common after RYGB and folate serum mean levels were higher after RYGB. SG causes less nutrient deficiency and is therefore a better technique from this point of view. More studies are needed on B2, B3, and B6 vitamins to draw better conclusions.

© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Keywords

• Bariatric surgery; Obesity; Roux-en-Y gastric bypass; Sleeve gastrectomy; Vitamin B complex deficiencies