Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • Pedro Miguel Araújo Campos De Castro

    Autor

Participantes de fora da FMUP

  • Panerai, RB
  • Brassard, P
  • Burma, JS
  • Claassen, JAHR
  • van Lieshout, JJ
  • Liu, J
  • Lucas, SJ
  • Minhas, JS
  • Mitsis, GD
  • Nogueira, RC
  • Ogoh, S
  • Payne, SJ
  • Rickards, CA
  • Robertson, AD
  • Rodrigues, GD
  • Smirl, JD
  • Simpson, DM
  • Cerebrovasc Res Network CARNet

Unidades de investigação

Abstract

Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in response to changes in perfusion pressure. Due to the challenges of measuring intracranial pressure, CA is often described as the relationship between mean arterial pressure (MAP) and CBF. Dynamic CA (dCA) can be assessed using multiple techniques, with transfer function analysis (TFA) being the most common. A 2016 white paper by members of an international Cerebrovascular Research Network (CARNet) that is focused on CA strove to improve TFA standardization by way of introducing data acquisition, analysis, and reporting guidelines. Since then, additional evidence has allowed for the improvement and refinement of the original recommendations, as well as for the inclusion of new guidelines to reflect recent advances in the field. This second edition of the white paper contains more robust, evidence-based recommendations, which have been expanded to address current streams of inquiry, including optimizing MAP variability, acquiring CBF estimates from alternative methods, estimating alternative dCA metrics, and incorporating dCA quantification into clinical trials. Implementation of these new and revised recommendations is important to improve the reliability and reproducibility of dCA studies, and to facilitate inter-institutional collaboration and the comparison of results between studies.

Dados da publicação

ISSN/ISSNe:
0271-678X, 1559-7016

Journal of Cerebral Blood Flow and Metabolism  SAGE Publications Inc.

Tipo:
Review
Páginas:
3-25
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 39

Citações Recebidas na Scopus: 72

Documentos

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Keywords

  • Cerebral hemodynamics; consensus guidelines; reference values; transfer function analysis

Financiamento

Proyectos asociados

A Resposta Inflamatória Sistémica está ligada com a Severidade do Edema Cerebral e Deterioração Neurológica após Recanalização em AVC isquémico

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Estudo Clínico Académico (AVC isquémico) . 2020

Microemboli After Successful Thrombectomy Do Not Affect Outcome But Predict New Embolic Events

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Estudo Clínico Académico (Thrombectomy) . 2020

Regulação Autonómica em Pacientes com Doença Arterial Aterosclerótica Intracraniana

Investigador Principal: Pedro Miguel Araújo Campos de Castro

Estudo Clínico Académico (AA) . 2020

Anemia and its association with global disability outcomes in stroke patients who underwent reperfusion therapy

Investigador Principal: Pedro Miguel Araújo Campos de Castro

Estudo Clínico Académico . 2021

Time trends, collaterals and cerebral autoregulation efficacy in acute ischemic stroke

Investigador Principal: Pedro Miguel Araújo Campos de Castro

Estudo Clínico Académico . 2021

Dynamic transcranial Doppler assessment in Heart Failure patients

Investigador Principal: Pedro Miguel Araújo Campos de Castro

Estudo Clínico Académico . 2020

The Impact of Very Short-term Variability of Blood Pressure in Outcome after Successful Thrombectomy

Investigador Principal: Pedro Miguel Araújo Campos de Castro

Estudo Clínico Académico . 2020

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