Poor Rhinitis and Asthma Control Is Associated With Decreased Health-Related Quality of Life and Utilities: A MASK-air Study.

Data de publicação: 01/06/2024 Data Ahead of Print: 30/03/2024

Autores da FMUP

Luís Filipe Ribeiro De Azevedo

Autor
João De Almeida Lopes Da Fonseca

Autor
Bernardo Manuel De Sousa Pinto

Autor

Participantes de fora da FMUP

Vieira RJ
Leemann L
Briggs A
Pereira AM
Savouré M
Kuna P
Morais-Almeida M
Bewick M
Louis R
Klimek L
Bahbah F
Samolinski B
Anto JM
Zuberbier T
Bousquet J
MASK-air Think Tank

Unidades de investigação

Laboratório Associado RISE- Rede de Investigação em Saúde

Investigador

Fernando Carlos De Landér Schmitt
Medicina da Comunidade, Informação e Decisão em Saúde
RISE-Health

Investigador

Fernando Carlos De Landér Schmitt

Abstract

BACKGROUND: Allergic rhinitis (AR) and asthma may affect health-related quality of life. However, national estimates on the quality of life of patients with AR or asthma are lacking. OBJECTIVE: To provide estimates for utility scores and EuroQoL five-dimension (EQ-5D) visual analog scale (VAS) for patients with AR or asthma. METHODS: We conducted a cross-sectional study using direct patient data from the MASK-air app on European MASK-air users with self-reported AR or asthma. We used a multi-attribute instrument (EQ-5D) to measure quality of life (as utility scores and EQ-5D VAS values). Mean scores were calculated per country and disease control level using multilevel regression models with poststratification, accounting for age and sex biases. RESULTS: We assessed data from 7905 MASK-air users reporting a total of up to 82,737 days. For AR, utilities ranged from 0.86 to 0.99 for good control versus 0.72 to 0.85 for poor control; EQ-5D VAS levels ranged from 78.9 to 87.9 for good control versus 55.3 to 64.2 for poor control. For asthma, utilities ranged from 0.84 to 0.97 for good control versus 0.73 to 0.87 for poor control; EQ-5D VAS levels ranged from 68.4 to 81.5 for good control versus 51.4 to 64.2 for poor control. Poor disease control was associated with a mean loss of 0.14 utilities for both AR and asthma. For the same control levels, AR and asthma were associated with similar utilities and EQ-5D VAS levels. However, lower values were observed for asthma plus AR compared with AR alone. CONCLUSIONS: Poor AR or asthma control are associated with reduced quality of life. The estimates obtained from mobile health data may provide valuable insights for health technology assessment studies.

Dados da publicação

ISSN/ISSNe:: 2213-2198, 2213-2201
Tipo:: Article
Páginas:: 1530-15386
DOI:: 10.1016/j.jaip.2024.03.036
Link para outro recurso:: www.scopus.com

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Vieira RJ:: Department of Community Medicine, Information, and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

Centre for Health Technology and Services Research, Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, Porto, Portugal
Leemann L:: Department of Political Science, University of Zurich, Zurich, Switzerland
Briggs A:: Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom
Pereira AM:: Department of Community Medicine, Information, and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

Centre for Health Technology and Services Research, Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, Porto, Portugal
Savouré M:: Inserm, Equipe d'Epidémiologie Respiratoire Intégrative, CESP, Villejuif, France

Université Paris-Saclay, Université de Versailles Saint-Quentin-en-Yvelines, Université Paris-Sud, Villejuif, France
Kuna P:: Division of Internal Medicine, Asthma, and Allergy, Barlicki University Hospital, Medical University of Lodz, Lodz, Poland
Morais-Almeida M:: Allergy Center, CUF Descobertas Hospital, Lisbon, Portugal
Bewick M:: University of Central Lancashire Medical School, Preston, United Kingdom
Azevedo LF:: Department of Community Medicine, Information, and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

Centre for Health Technology and Services Research, Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, Porto, Portugal
Louis R:: Department of Pulmonary Medicine, CHU Liège, Liège, Belgium

GIGA I3 Research Group, University of Liège, Liège, Belgium
Klimek L:: Department of Otolaryngology, Head and Neck Surgery, Universitätsmedizin Mainz, Mainz, Germany

Center for Rhinology and Allergology, Wiesbaden, Germany
Bahbah F:: Stallergenes Greer, Ltd, Antony, France
Samolinski B:: Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland
Anto JM:: ISGlobAL, Barcelona Institute for Global Health, Barcelona, Spain

Universitat Pompeu Fabra, Barcelona, Spain

CIBER Epidemiología y Salud Pública, Barcelona, Spain
Zuberbier T:: Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

Fraunhofer Institute for Translational Medicine and Pharmacology, Allergology and Immunology, Berlin, Germany
Fonseca JA:: Department of Community Medicine, Information, and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

Centre for Health Technology and Services Research, Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, Porto, Portugal
Bousquet J:: Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

Fraunhofer Institute for Translational Medicine and Pharmacology, Allergology and Immunology, Berlin, Germany

MASK-air SAS, Montpellier, France
Sousa-Pinto B:: Department of Community Medicine, Information, and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

Centre for Health Technology and Services Research, Health Research Network (CINTESIS@RISE), Faculty of Medicine, University of Porto, Porto, Portugal

Keywords

Allergic rhinitis; Asthma; EQ-5D-5L; Health-related quality of life; Mobile health; Quality of life; Real-world data; Utilities