Impact of Allergic Rhinitis Control on Work Productivity and Costs: A Real-World Data MASK-air Study.

Data de publicação: 01/11/2024 Data Ahead of Print: 05/08/2024

Autores da FMUP

Luís Filipe Ribeiro De Azevedo

Autor
João De Almeida Lopes Da Fonseca

Autor
Bernardo Manuel De Sousa Pinto

Autor

Participantes de fora da FMUP

Vieira RJ
Pereira AM
Nogueira-Leite D
Rocha Gonçalves FN
Larenas-Linnemann DE
Cruz AA
Gemicioglu B
Samolinski B
de Las Vecillas L
Giovannini M
Cunha MJ
Rodrigues J
Kvedariene V
Klimek L
Pfaar O
Zuberbier T
Bousquet J

Unidades de investigação

Laboratório Associado RISE- Rede de Investigação em Saúde

Investigador

Fernando Carlos De Landér Schmitt
Medicina da Comunidade, Informação e Decisão em Saúde
RISE-Health

Investigador

Fernando Carlos De Landér Schmitt

Abstract

BACKGROUND: Allergic rhinitis (AR) has a substantial socioeconomic impact associated with impaired work productivity. OBJECTIVE: To study the impact of AR on work productivity and estimate the corresponding indirect costs for 40 countries. METHODS: We conducted a cross-sectional study using direct patient data from the MASK-air app on users with self-reported AR. We used the Work Productivity and Activity Impairment Questionnaire: Allergy Specific to measure the impact of AR on work productivity (presenteeism and absenteeism). Weekly indirect costs were estimated per country for each level of rhinitis control. Patients with and without asthma were considered. RESULTS: We assessed data from 677 weeks (364 patients), 280 of which were reported by patients with asthma. Regarding presenteeism, the median impact of AR in weeks of poor disease control was 60.7% (percentiles 25-75 [P25-P75] 24.9%-74.2%), whereas partial and good disease control were, respectively, associated with an impact of 25.0% (P25-P75 12.1%-42.4%) and 4.4% (P25-P75 0.8%-12.9%). In poorly controlled weeks, presenteeism was associated with indirect costs ranging from 65.7 US$ purchase power parities (PPPs) (P25-P75 29.2-143.2) in Brazil to 693.6 US$ PPP (P25-P75 405.2-1,094.9) in Iceland. Median absenteeism per week was of 0% for all levels of rhinitis control. Patients with AR + asthma showed higher overall work impairment than patients with AR alone, particularly in poorly controlled weeks (median work impairment in AR alone 39.1% [P25-P75 12.5%-71.9%]; median work impairment in AR + asthma 68.4% [P25-P75 54.6%-80.2%]). CONCLUSIONS: Poor AR control was associated with decreased work productivity and increased indirect costs, particularly in patients with AR + asthma. The estimates from this study underpin the economic burden of AR.

Dados da publicação

ISSN/ISSNe:: 2213-2198, 2213-2201
Tipo:: Article
Páginas:: 3107-311513
DOI:: 10.1016/j.jaip.2024.07.026
Link para outro recurso:: www.scopus.com

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Vieira RJ:: MEDicina da Comunidade, Informação e Decisão em Saúde (MEDCIDS)-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

CINTESIS@RISE-Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Azevedo LF:: MEDicina da Comunidade, Informação e Decisão em Saúde (MEDCIDS)-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

CINTESIS@RISE-Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Pereira AM:: MEDicina da Comunidade, Informação e Decisão em Saúde (MEDCIDS)-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

PaCeIT-Patient Centered Innovation and Technologies, Center for Health Technology and Services Research (CINTESIS), Faculty of Medicine, University of Porto, Porto, Portugal

Allergy Unit, Institute and Hospital Companhia União Fabril (CUF) (Instituto and Hospital Companhia União Fabril - CUF), Porto, Portugal
Nogueira-Leite D:: MEDicina da Comunidade, Informação e Decisão em Saúde (MEDCIDS)-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

CINTESIS@RISE-Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Rocha Gonçalves FN:: MEDicina da Comunidade, Informação e Decisão em Saúde (MEDCIDS)-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

CINTESIS@RISE-Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Larenas-Linnemann DE:: Center of Excellence in Asthma and Allergy, Médica Sur Clinical Foundation and Hospital, México City, Mexico
Cruz AA:: PROfessionals of Asthma and Respiratory Foundation (Fundaçao ProAR), Federal University of Bahia and GARD/WHO Planning Group, Salvador, Bahia, Brazil
Gemicioglu B:: Department of Pulmonary Diseases, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey

Institute of Pulmonology and Tuberculosis, Istanbul University-Cerrahpasa, Istanbul, Turkey
Samolinski B:: Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland
de Las Vecillas L:: Department of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain
Giovannini M:: Allergy Unit, Meyer Children's Hospital - Istituto di Ricovero e Cura a Carattere Scientifico - IRCCS (Scientific Institute for Hospitalization and Care), Florence, Italy

Department of Health Sciences, University of Florence, Florence, Italy
Cunha MJ:: Amadeo de Souza-Cardoso Family Health Unit, Tâmega I Health Center Group (Unidade de Saúde Familiar Amadeo de Souza-Cardoso, Agrupamento de Centros de Saúde Tâmega I), Amarante, Portugal
Rodrigues J:: CINTESIS@RISE-Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal

Otorhinolaryngology Department, Sao Joao University Hospital Center (Centro Hospitalar Universitário de Sao João), Porto, Portugal

Unit of Anatomy, Department of Biomedicine, Faculty of Medicine, University of Porto, Porto, Portugal
Kvedariene V:: Institute of Clinical Medicine, Clinic of Chest Diseases and Allergology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania

Institute of Biomedical Sciences, Department of Pathology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
Klimek L:: Department of Otolaryngology, Head and Neck Surgery, University Medicine of Mainz (Universitätsmedizin Mainz), Mainz, Germany

Center for Rhinology and Allergology, Wiesbaden, Germany
Pfaar O:: Section of Rhinology and Allergy, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany
Zuberbier T:: Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany

Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
Fonseca JA:: MEDicina da Comunidade, Informação e Decisão em Saúde (MEDCIDS)-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

CINTESIS@RISE-Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal
Bousquet J:: Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology, Berlin, Germany

Institute of Allergology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

Inserm Equipe d'Epidémiologie Respiratoire Intégrative, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), Villejuif, France

Allergic Rhinitis and its Impact on Asthma (ARIA), Montpellier, France

MASK-air, Montpellier, France
Sousa-Pinto B:: MEDicina da Comunidade, Informação e Decisão em Saúde (MEDCIDS)-Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal

CINTESIS@RISE-Centre for Health Technology and Services Research, Health Research Network, Faculty of Medicine, University of Porto, Porto, Portugal

Keywords

Allergic rhinitis; Asthma; Indirect costs; Presenteeism; Work productivity