Prevalence of non-neurogenic male lower urinary tract symptoms after kidney transplantation

Autores da FMUP

• Maria Teresa Pina Vaz Gonçalves Rodrigues

  Autor

• Tiago Vieira Da Conceicao Antunes Lopes

  Autor

Participantes de fora da FMUP

• Silva, Alberto Costa
• Morgado, Afonso
• Martins-Silva, Carlos
• Silva, Joao Alturas

Unidades de investigação

• Cirurgia e Fisiologia

• RISE-Health

  

  Investigador

  Fernando Carlos De Landér Schmitt

Abstract

ObjectiveThis review investigates the prevalence of male non-neurogenic lower urinary tract symptoms (LUTS) after renal transplant, as kidney transplantation is a transformative intervention for patients with end-stage renal disease significantly enhancing quality of life that might be diminished by LUTS.MethodsThe Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. A systematic search in the PubMed and Scopus databases was performed using specific terms. Inclusion criteria considered male kidney transplant recipients, analysing outcomes in English-language studies. Discrepancies were resolved by consultation.ResultsAmong 18 studies involving 29 086 recipients, the prevalence of non-neurogenic LUTS ranged from 5.8% to 33.0%. Studies predominantly used the International Prostate Symptom Score for evaluation. Surgical interventions, mostly for benign prostatic obstruction, ranged from 2.5% to 20.0%. Voiding and post-micturition symptoms were under-represented.ConclusionThis review found varied non-neurogenic LUTS prevalence and characteristics in male kidney transplant recipients, emphasising the need for standardised assessments, prospective studies, and improved understanding of LUTS mechanisms. Enhanced knowledge can guide interventions, additionally benefiting recipient quality of life.

Keywords

• kidney transplantation; lower urinary tract symptoms; benign prostatic hyperplasia; Urologic surgical procedures