Empowerment-based nutrition interventions on blood pressure: a randomized comparative effectiveness trial

Data de publicação:

Autores da FMUP

  • Jorge Manuel Da Silva Junqueira Polónia

    Autor

  • Maria Da Conceição Costa Pinho Calhau

    Autor

Participantes de fora da FMUP

  • Moreira-Rosario, Andre
  • Ismael, Shamila
  • Barreiros-Mota, Ines
  • Morais, Juliana
  • Rodrigues, Catarina
  • Castela, Ines
  • Mendes, Ines Curvelo
  • Soares, Maria Ines
  • da Costa, Luis Soares
  • Oliveira, Catarina Batista
  • Henriques, Tiago
  • Pinto, Patricia
  • Pita, Debora
  • de Oliveira, Catarina Marques
  • Maciel, Janaina
  • Serafim, Thaina
  • Araujo, Joao
  • Rocha, Julio Cesar
  • Pestana, Diogo
  • Silvestre, Marta P.
  • Marques, Claudia
  • Faria, Ana

Unidades de investigação

Abstract

IntroductionEmpowerment lifestyle programs are needed to reduce the risk of hypertension. Our study compared the effectiveness of two empowerment-based approaches toward blood pressure (BP) reduction: salt reduction-specific program vs. healthy lifestyle general program.MethodsThree hundred and eleven adults (median age of 44 years, IQR 34-54 years) were randomly assigned to a salt reduction (n = 147) or a healthy lifestyle program (n = 164). The outcome measures were urinary sodium (Na+) and potassium (K+) excretion, systolic (SBP) and diastolic (DBP) blood pressure, weight, and waist circumference.ResultsThere were no significant differences in primary and secondary outcomes between the two program groups. When comparing each program to baseline, the program focused on salt reduction was effective in lowering BP following a 12-week intervention with a mean change of -2.5 mm Hg in SBP (95% CI, -4.1 to -0.8) and - 2.7 mm Hg in DBP (95% CI, -3.8 to -1.5) in the intention-to-treat (ITT) analysis. In the complete-case (CC) analysis, the mean change was -2.1 mm Hg in SBP (95% CI, -3.7 to -0.5) and - 2.3 mm Hg in DBP (95% CI, -3.4 to -1.1). This effect increases in subjects with high-normal BP or hypertension [SBP - 7.9 mm Hg (95% CI, -12.5 to -3.3); DBP - 7.3 mm Hg (95% CI, -10.2 to -4.4)]. The healthy lifestyle group also exhibited BP improvements after 12 weeks; however, the changes were less pronounced compared to the salt reduction group and were observed only for DBP [mean change of -1.5 mm Hg (95% CI, -2.6 to -0.4) in ITT analysis and - 1.4 mm Hg (95% CI, -2.4 to -0.3) in CC analysis, relative to baseline]. Overall, improvements in Na+/K+ ratio, weight, and Mediterranean diet adherence resulted in clinically significant SBP decreases. Importantly, BP reduction is attributed to improved dietary quality, rather than being solely linked to changes in the Na+/K+ ratio.ConclusionSalt-focused programs are effective public health tools mainly in managing individuals at high risk of hypertension. Nevertheless, in general, empowerment-based approaches are important strategies for lowering BP, by promoting health literacy that culminates in adherence to the Mediterranean diet and weight reduction.

Dados da publicação

ISSN/ISSNe:
2296-2565, 2296-2565

Frontiers in Public Health  Frontiers Media S.A.

Tipo:
Article
Páginas:
-
Link para outro recurso:
www.scopus.com

Citações Recebidas na Scopus: 1

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Keywords

  • cardiovascular diseases; hypertension; blood pressure; mediterranean diet; sodium/potassium ratio

Campos de estudo

Proyectos asociados

Comparison of Blood Pressure Variability Between 24H Ambulatory Monitoring and Office Blood Pressure in Diabetics and Non-diabetic Patients a Cross-Sectional Study.

Investigador Principal: Jorge Manuel da Silva Junqueira Polónia

Estudo Clínico Académico . 2021

Hipertensão da bata branca: prognóstico cardiovascular quando definida pela normalidade da pressão arterial noturna.

Investigador Principal: Jorge Manuel da Silva Junqueira Polónia

Estudo Clínico Académico . 2022

Unraveling the Effects of Anthocyanins in Metabolic Health and Disease: Insights on Bioavailability and Gut Microbiota Modulation

Investigador Principal: Maria da Conceição Costa Pinho Calhau

Estudo Clínico Académico . 2019

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