1. Início
  2. Publicações
  3. Pan-Enteric Capsule Endoscopy: Current Applications and Future Perspectives

Pan-Enteric Capsule Endoscopy: Current Applications and Future Perspectives

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • Manuel Guilherme Gonçalves Macedo

    Autor

Participantes de fora da FMUP

  • Rosa, Bruno
  • Andrade, Patricia
  • Lopes, Sandra
  • Goncalves, Ana Rita
  • Serrazina, Juliana
  • Cardoso, Pedro Marilio
  • Silva, Andrea
  • Silva, Vitor Macedo
  • Cotter, Jose
  • Figueiredo, Pedro Narra
  • Chagas, Cristina

Unidades de investigação

Abstract

Background: The role of capsule endoscopy in the evaluation of the small bowel is well established, and current guidelines position it as a first-line test in a variety of clinical scenarios. The advent of double-headed capsules further enabled the endoscopic assessment of colonic mucosa and the opportunity for a one-step noninvasive examination of the entire bowel (pan-enteric capsule endoscopy [PCE]). Summary: We reviewed the technical procedure and preparation of patients for PCE, as well as its current clinical applications and future perspectives. In non-stricturing and non-penetrating Crohn's disease affecting the small bowel and colon, PCE monitors disease activity by assessing mucosal healing, a major treatment outcome, with a higher diagnostic yield than cross-sectional imaging or conventional colonoscopy. Also in ulcerative colitis, double-headed capsules have been used to monitor disease activity noninvasively. Currently, validated scoring systems have been specifically devised for these double-headed capsules and permit a standardized assessment of the inflammatory burden. In suspected mid-lower digestive bleeding, some exploratory studies have demonstrated the feasibility and high diagnostic yield of PCE, which may work as a filter indicating which patients may benefit of further invasive procedures, namely, for planned hemostatic procedures. The possibility of using PCE is also discussed in the context of polyposis syndromes with simultaneous involvement of the small intestine and colon. Key Messages: PCE is a feasible, effective, and safe diagnostic procedure to evaluate the small bowel and colon. It has been increasingly explored in the setting of inflammatory bowel diseases and, more recently, in suspected mid-lower digestive bleeding. PCE is expected to reduce the demand for invasive procedures and expand the scope of noninvasive intestinal evaluation in the coming future.

Dados da publicação

ISSN/ISSNe:
2341-4545, 2387-1954

GE Portuguese Journal of Gastroenterology  Karger AG

Tipo:
Review
Páginas:
89-100
PubMed:
38572440
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 10

Citações Recebidas na Scopus: 11

Documentos

  • Não há documentos

Métricas

Filiações mostrar / ocultar

Keywords

  • Capsule endoscopy; Pan-enteric endoscopy; Digestive bleeding; Inflammatory bowel disease; Crohn's disease; Capsula endoscopica; Endoscopia pan-enterica; Hemorragia digestiva; Doenca inflamatoria intestinal; Doenca de Crohn

Projetos associados

The contribution of endoscopic ultrasound and biomarkers in the management of pancreatic adenocarcinoma and its precursor lesions.

Investigador Principal: Manuel Guilherme Gonçalves Macedo

Estudo Clínico Académico . 2023

Noninvasive serum biomarkers of portal hypertension in liver cirrhosis

Investigador Principal: Manuel Guilherme Gonçalves Macedo

Estudo Clínico Académico . 2023

Otimização do rendimento da colangiopancreatografia retrógrada endoscópica na avaliação das estenoses pancreato-biliares indeterminadas

Investigador Principal: Manuel Guilherme Gonçalves Macedo

Estudo Clínico Académico . 2023

Endoscopic Treatment Of Upper Gastrointestinal Postsurgical Leaks

Investigador Principal: Manuel Guilherme Gonçalves Macedo

Estudo Clínico Académico . 2023

Citar a publicação

Partilhar a publicação