Practical management of mild-to-moderate ulcerative colitis: an international expert consensus

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • Fernando José Magro Dias

    Autor

Participantes de fora da FMUP

  • D'Amico, Ferdinando
  • Dignass, Axel
  • Al Awadhi, Sameer
  • Gutierrez Casbas, Ana
  • Queiroz, Natalia Sousa Freitas
  • Rydzewska, Grazyna
  • Duk Ye, Byong
  • Ran, Zhihua
  • Hart, Ailsa
  • Jairath, Vipul
  • Fiorino, Gionata
  • Peyrin-Biroulet, Laurent
  • Danese, Silvio

Unidades de investigação

Abstract

IntroductionAlthough there are well-defined guidelines for the management of mild-to-moderate ulcerative colitis (UC), there are still unmet needs. For this reason, we conducted an international expert consensus to standardize the management of patients with mild-to-moderate UC and provide practical guidance to clinicians.Areas coveredBased on Delphi methodology, 15 statements were approved after two rounds of voting, addressing several aspects of disease management from sequencing to treatment duration, from monitoring to optimization techniques and safety profile.Expert opinionGrowing knowledge of mild-to-moderate UC has led to the development of new ambitious outcomes such as histological remission and disease clearance. Furthermore, noninvasive tools for patient monitoring such as fecal calprotectin and intestinal ultrasound are now available. Their implementation in clinical practice will allow clinicians to tightly monitor disease activity and promptly adapt treatment, avoiding complications and disease progression and targeting better disease control.

Dados da publicação

ISSN/ISSNe:
1747-4132, 1747-4124

EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY  Taylor and Francis Ltd.

Tipo:
Review
Páginas:
421-430
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 1

Citações Recebidas na Scopus: 1

Documentos

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Métricas

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Keywords

  • Ulcerative colitis; inflammatory bowel disease; mesalamine; 5-ASA; budesonide MMX

Proyectos asociados

Gut microbiome and IBD therapy: an interplay?

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Estudo Observacional Académico (GutIBD) . 2021

Iron deficiency and inflammatory bowel disease. Correlation with inflammation and Vitamin D status.

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Estudo Observacional Académico (IronIBD) . 2021

Looking 4WARD: The role of dipeptidyl peptidase 4 (DPP-4) in inflammatory bowel disease (IBD) as a novel biomarker for predicting disease activity and monitoring response to therapy in IBD patients.

Investigador Principal: Fernando José Magro Dias

Estudo Observacional Académico (4WARD) . 2021

Isolated Ulceration of Crohn’s Anastomosis

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Estudo Clínico Académico . 2021

Histologic Features of Colon Biopsies (Geboes Score) Associated With Progression of Ulcerative Colitis for the First 36 Months After Biopsy

Investigador Principal: Fernando José Magro Dias

Estudo Clínico Académico . 2022

Burden of Inflammatory Bowel Disease in Portugal

Investigador Principal: Fernando José Magro Dias

Estudo Clínico Académico (Inflammatory Bowel) . 2023

Therapeutic Drug Monitoring: An Emergent Approach in Inflammatory Bowel Disease

Investigador Principal: Fernando José Magro Dias

Estudo Clínico Académico . 2021

Contributo da endoscopia, biomarcadores e imagiologia na evolução clinica dos doentes com doença inflamatória intestinal

Investigador Principal: Fernando José Magro Dias

Estudo Clínico Académico . 2019

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