Practical management of mild-to-moderate ulcerative colitis: an international expert consensus

Autores da FMUP
Participantes de fora da FMUP
- D'Amico, Ferdinando
- Dignass, Axel
- Al Awadhi, Sameer
- Gutierrez Casbas, Ana
- Queiroz, Natalia Sousa Freitas
- Rydzewska, Grazyna
- Duk Ye, Byong
- Ran, Zhihua
- Hart, Ailsa
- Jairath, Vipul
- Fiorino, Gionata
- Peyrin-Biroulet, Laurent
- Danese, Silvio
Unidades de investigação
Abstract
IntroductionAlthough there are well-defined guidelines for the management of mild-to-moderate ulcerative colitis (UC), there are still unmet needs. For this reason, we conducted an international expert consensus to standardize the management of patients with mild-to-moderate UC and provide practical guidance to clinicians.Areas coveredBased on Delphi methodology, 15 statements were approved after two rounds of voting, addressing several aspects of disease management from sequencing to treatment duration, from monitoring to optimization techniques and safety profile.Expert opinionGrowing knowledge of mild-to-moderate UC has led to the development of new ambitious outcomes such as histological remission and disease clearance. Furthermore, noninvasive tools for patient monitoring such as fecal calprotectin and intestinal ultrasound are now available. Their implementation in clinical practice will allow clinicians to tightly monitor disease activity and promptly adapt treatment, avoiding complications and disease progression and targeting better disease control.
Dados da publicação
- ISSN/ISSNe:
- 1747-4132, 1747-4124
- Tipo:
- Review
- Páginas:
- 421-430
- Link para outro recurso:
- www.scopus.com
EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY Taylor and Francis Ltd.
Citações Recebidas na Web of Science: 1
Citações Recebidas na Scopus: 1
Documentos
- Não há documentos
Filiações
Keywords
- Ulcerative colitis; inflammatory bowel disease; mesalamine; 5-ASA; budesonide MMX
Proyectos asociados
Gut microbiome and IBD therapy: an interplay?
Investigador Principal: Fernando José Magro Dias
Estudo Observacional Académico (GutIBD) . 2021
Iron deficiency and inflammatory bowel disease. Correlation with inflammation and Vitamin D status.
Investigador Principal: Fernando José Magro Dias
Estudo Observacional Académico (IronIBD) . 2021
Looking 4WARD: The role of dipeptidyl peptidase 4 (DPP-4) in inflammatory bowel disease (IBD) as a novel biomarker for predicting disease activity and monitoring response to therapy in IBD patients.
Investigador Principal: Fernando José Magro Dias
Estudo Observacional Académico (4WARD) . 2021
Isolated Ulceration of Crohn’s Anastomosis
Investigador Principal: Fernando José Magro Dias
Estudo Clínico Académico . 2021
Histologic Features of Colon Biopsies (Geboes Score) Associated With Progression of Ulcerative Colitis for the First 36 Months After Biopsy
Investigador Principal: Fernando José Magro Dias
Estudo Clínico Académico . 2022
Burden of Inflammatory Bowel Disease in Portugal
Investigador Principal: Fernando José Magro Dias
Estudo Clínico Académico (Inflammatory Bowel) . 2023
Therapeutic Drug Monitoring: An Emergent Approach in Inflammatory Bowel Disease
Investigador Principal: Fernando José Magro Dias
Estudo Clínico Académico . 2021
Contributo da endoscopia, biomarcadores e imagiologia na evolução clinica dos doentes com doença inflamatória intestinal
Investigador Principal: Fernando José Magro Dias
Estudo Clínico Académico . 2019
Citar a publicação
D'Amico F,Magro F,Dignass A,Al Awadhi S,Gutierrez A,Queiroz NSF,Rydzewska G,Duk B,Ran Z,Hart A,Jairath V,Fiorino G,Peyrin L,Danese S. Practical management of mild-to-moderate ulcerative colitis: an international expert consensus. Expert Rev. Gastroenterol. Hepatol. 2024. 18(8):p. 421-430. IF:3,900. (2).