Mushroom consumption and risk of gastric cancer: a pooled analysis within the stomach cancer pooling project and a combined meta-analysis with other observational studies

Data de publicação:

Autores da FMUP

  • Nuno Miguel De Sousa Lunet

    Autor

Participantes de fora da FMUP

  • Ba, Djibril M.
  • Ssentongo, Paddy
  • Pelucchi, Claudio
  • Negri, Eva
  • Palli, Domenico
  • Ferraroni, Monica
  • Zhang, Zuo-Feng
  • Yu, Guo-Pei
  • Tsugane, Shoichiro
  • Hidaka, Akihisa
  • Hamada, Gerson Shigueaki
  • Zaridze, David
  • Maximovich, Dmitry
  • Obon-Santacana, Mireia
  • Alvarez-Alvarez, Laura
  • Vioque, Jesus
  • Garcia de la Hera, Manoli
  • Lopez-Carrillo, Lizbeth
  • Lopez-Cervantes, Malaquias
  • Mu, Lina
  • Lagiou, Areti
  • Lagiou, Pagona
  • Boffetta, Paolo
  • Camargo, Maria Constanza
  • Curado, Maria Paula
  • La Vecchia, Carlo
  • Muscat, Joshua

Unidades de investigação

Abstract

Edible mushrooms have high concentrations of vitamins and minerals. They are considered `functional foods' for their disease-prevention properties. Mushroom consumption may reduce the risk of gastric cancer, the fifth most common cancer worldwide. We investigated the association between mushroom consumption and gastric cancer risk in a pooled analysis within the Stomach Cancer Pooling (StoP) Project and in a meta-analysis that also included previously published studies. A total of 3900 gastric cancer cases and 7792 controls from 11 studies were included in the StoP analysis. Mushroom consumption was measured using food frequency questionnaires. Higher mushroom consumption was associated with a lower risk of gastric cancer [relative risk (RR) for the highest vs. lowest consumption categories, 0.82; 95% confidence interval (CI), 0.71-0.95]. The corresponding RRs were 0.59 (95% CI, 0.26-1.33) in a meta-analysis of four previously published studies and 0.77 for all studies combined (95% CI, 0.63-0.95; n = 15 studies). In geographic subgroup analysis, the pooled risk in Western Pacific countries was (RR, 0.59; 95% CI, 0.40-0.87; n = 6). The stronger effect in Asian countries may reflect high level of antioxidants in mushroom species consumed in Asia.

Dados da publicação

ISSN/ISSNe:
1473-5709, 0959-8278

EUROPEAN JOURNAL OF CANCER PREVENTION  Lippincott Williams and Wilkins Ltd.

Tipo:
Article
Páginas:
222-228
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 2

Citações Recebidas na Scopus: 2

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Keywords

  • epidemiology; gastric cancer; meta-analysis; mushrooms; pooled analysis

Proyectos asociados

Breast cancer heterogeneity - etiology, clinical management, use of health resources and survival

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Estudo Clínico Académico . 2022

Longitudinal Assessment of Cognitive Decline in Breast and Prostate Cancer Survivors

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Estudo Clínico Académico (Cognitive Decline) . 2022

Healthcare use among cancer patients and their partners in different phases of the cancer pathway

Investigador Principal: Nuno Miguel de Sousa Lunet

Estudo Clínico Académico . 2021

Reshaping organized cervical cancer screening: strategies to increase the adherence and reduce invitation costs

Investigador Principal: Nuno Miguel de Sousa Lunet

Estudo Clínico Académico . 2020

Using pooled analyses based on individual participant data for a finer assessment of gastric cancer etiology

Investigador Principal: Nuno Miguel de Sousa Lunet

Estudo Clínico Académico . 2020

RISK AND SURVIVAL OF GASTRIC CANCER RELATES SECOND PRIMARY TUMOURS: A COMPETING RISKS FRAMEWORK

Investigador Principal: Nuno Miguel de Sousa Lunet

Estudo Clínico Académico . 2019

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