Preoperative risk factors for early postoperative bleeding after Roux-en-Y gastric bypass surgery: a systematic review and meta-analysis

Data de publicação:

Autores da FMUP

  • Hugo Miguel Teixeira Ferraz Santos Sousa

    Autor

  • André Manuel Costa Pinho

    Autor

  • Bernardo Manuel De Sousa Pinto

    Autor

Participantes de fora da FMUP

  • Amorim-Cruz, Filipe
  • Nogueiro, Jorge
  • Silva, Alexandre
  • Amorim-Cruz, Ines
  • Ferreira-Santos, Rui
  • Bouca-Machado, Raquel
  • Pereira, Andre
  • Resende, Fernando
  • Preto, John
  • Lima-da-Costa, Eduardo
  • Barbosa, Elisabete
  • Carneiro, Silvestre

Unidades de investigação

Abstract

Purpose Although bariatric surgery is an effective intervention for obesity, it comes with risks such as early postoperative bleeding (EPB). Identifying preoperative risk factors for this complication can help patients' risk stratification and optimization. We performed a systematic review and meta-analysis to find predictors for early postoperative bleeding after Roux-en-Y gastric bypass (RYGB). Methods We conducted a systematic review, searching PubMed, Cochrane Library, and Web of Science until November 2023. We performed a random-effects meta-analysis to explore preoperative risk factors associated with early postoperative bleeding after RYGB. Sources of heterogeneity were explored by leave-one-out analyses. Results 23 studies were included, comprising 232,488 patients. Male gender (meta-analytical RR = 1.42, 95%CI = 1.21-1.66, I-2 = 18%, Q Cochran test p-value = 0.29) and revisional surgery (meta-analytical RR = 1.35, 95%CI = 1.12-1.62, I-2 = 22%, Q Cochran test p = 0.21) were associated with higher risk of EPB. On average, patients with EPB were older than the remainder (MD for the mean age = 2.82 years, 95%CI = 0.97-4.67, I-2 = 0.00%, Q Cochran test p = 0.46). Except for hypertension (meta-analytical RR = 1.33, 95%CI = 1.02-1.73, I-2 = 66%, Q Cochran test p < 0.0001), comorbidities were not associated with a higher risk of EPB. Conclusion Preoperative risk factors, including age, gender, hypertension, and revisional bariatric surgery, are associated with early postoperative bleeding after RYGB. Further primary studies, with higher methodological quality, are required to detail more risk factors.

Dados da publicação

ISSN/ISSNe:
1435-2451, 1435-2443

LANGENBECKS ARCHIVES OF SURGERY  Springer Verlag

Tipo:
Review
Páginas:
-
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 1

Citações Recebidas na Scopus: 1

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Keywords

  • Bariatric surgery; Obesity; Roux-en-Y gastric bypass; Risk factors; Hemorrhage

Proyectos asociados

Impact of Platelet-Lymphocyte Ratio (PLR) in the prognosis of Gastric Cancer patients

Investigador Principal: Hugo Miguel Teixeira Ferraz Santos Sousa

Estudo Clínico Académico (PLR) . 2020

Impact of serum albumin concentration and neutrophil-lymphocyte ratio score on gastric cancer prognosis

Investigador Principal: Hugo Miguel Teixeira Ferraz Santos Sousa

Estudo Clínico Académico (gastric cancer prognosis . 2020

Nutritional deficiencies in bariatric surgery patients: a comparison between Roux-en-Y Gastric Bypass and Sleeve Gastrectomy

Investigador Principal: Hugo Miguel Teixeira Ferraz Santos Sousa

Estudo Clínico Académico . 2021

Resultados a curto prazo do Bypass Gástrico vs Sleeve Gástrico na Super Obesidade: análise num único centro

Investigador Principal: André Manuel Costa Pinho

Estudo Clínico Académico . 2021

Roux-en-Y Gastric Bypass and Sleeve Gastrectomy as Revisional Bariatric Procedures after Adjustable Gastric Banding: a retrospective cohort study

Investigador Principal: Hugo Miguel Teixeira Ferraz Santos Sousa

Estudo Clínico Académico (Gastric Bypass) . 2021

Seroprevalence of SARS-CoV-2 and assessment of epidemiologic determinants in Portuguese municipal workers

Investigador Principal: Bernardo Manuel De Sousa Pinto

Estudo Clínico Académico (SARS-CoV-2) . 2021

Early postoperative bleeding after Laparoscopic Roux-En-Y Gastric Bypass: a single center analysis

Investigador Principal: André Manuel Costa Pinho

Estudo Clínico Académico . 2021

Health related Quality of Life six years after bariatric surgery: factors influencing outcome

Investigador Principal: André Manuel Costa Pinho

Estudo Clínico Académico . 2020

High-Sensitivity modified Glasgow Prognostic Score (HS-mGPS) as a predictor of overall survival in gastric cancer patients submitted to curative-intent surgery

Investigador Principal: Hugo Miguel Teixeira Ferraz Santos Sousa

Estudo Clínico Académico . 2020

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