Portal de investigação
Adequate magnesium level as an associated factor of pre-diabetes and diabetes mellitus remission in patients with obesity submitted to bariatric surgery
Data de publicação:
Autores da FMUP
Participantes de fora da FMUP
- Guerreiro, Vanessa
- Maia, Isabel
- Salazar, Daniela
- Ferreira, Maria Joao
- Mendonca, Fernando
- Silva, Maria Manuel
- Viana, Sara
- Costa, Claudia
- Varela, Ana
- Lau, Eva
Unidades de investigação
Abstract
Bariatric surgery (BS) can lead to remission of type 2 diabetes mellitus (T2DM), however, the evidence on the influence of preoperative serum magnesium levels on this reversal is scarce. To study the influence of preoperative serum magnesium levels on the pre-T2DM and T2DM remission one year after BS. Retrospective study carried out among 1656 patients with obesity who underwent BS in the Centro Hospitalar Universitario SAo JoAo. T2DM and pre-T2DM remission were defined as being normal glycaemic measures of at least one year's after BS and without pharmacological therapy. To assess the association between preoperative serum magnesium levels and pre- and T2DM remission, logistic regression models, crude and adjusted for sex, age and body mass index were computed. Patients with normoglycaemia presented hypomagnesaemia less often than those patients with pre-T2DM and T2DM (17.0% vs. 21.3% vs. 39.9%) (p<0.001). One year after BS, 62.9% of patients with pre-T2DM or T2DM before BS showed remission. Adequate magnesium levels were positively associated with T2DM and pre-T2DM remission, one year after BS (OR1.79; 95% CI 1.34-2.38), independently of sex, age, and body mass index. Adequate preoperative serum magnesium levels showed to be an important clinical parameter for pre-T2DM and T2DM remission.
Dados da publicação
- ISSN/ISSNe:
- 2045-2322, 2045-2322
- Tipo:
- Article
- Páginas:
- 21223-
- Link para outro recurso:
- www.scopus.com
Scientific Reports Nature Publishing Group
Citações Recebidas na Web of Science: 2
Citações Recebidas na Scopus: 1
Documentos
- Não há documentos
Filiações
Keywords
- MEDIATED GLUCOSE DISPOSAL; BETA-CELL FUNCTION; GASTRIC BYPASS; INSULIN-RESISTANCE; HYPOMAGNESEMIA; HOMEOSTASIS; DEFICIENCY
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Citar a publicação
Guerreiro V,Maia I,Neves JS,Salazar D,Ferreira MJ,Mendonca F,Silva MM,Viana S,Costa C,Pedro J,Varela A,Lau E,Freitas P,Carvalho D. Adequate magnesium level as an associated factor of pre-diabetes and diabetes mellitus remission in patients with obesity submitted to bariatric surgery. Sci. Rep. 2021. 11. (1):p. 21223-21223. IF:4,996. (2).
