Cushing's Syndrome Behind Hypokalemia and Severe Infection: A Case Report

Data de publicação:

Autores da FMUP

  • Daniela Santos Oliveira

    Autor

  • Ana Patricia Martins Lourenco

    Autor

Participantes de fora da FMUP

  • Elias, C
  • Silva, MM

Unidades de investigação

Abstract

Cushing's syndrome (CS) is a rare condition associated with increased morbidity and mortality. Complications derive from hypercortisolism and are mainly cardiovascular, infectious and thrombotic. Most manifestations are unspecific, and the diagnosis is frequently delayed and made only in the setting of complications.We present a woman in whom CS was investigated because of refractory hypokalemia, hypernatremia and metabolic alkalosis. The patient had many cardiovascular risk factors and was admitted to the hospital due to a serious bacterial infection -muscle abscesses evolving into osteomyelitis. The final etiological diagnosis was not possible because the acute event had a fatal outcome.Immunosuppression associated with hypercortisolism makes these patients predisposed to severe infection. Indeed, infectious complications are a relevant cause of death in CS. Diagnosing and treating CS early is paramount in preventing its dismal complications.

Dados da publicação

ISSN/ISSNe:
2168-8184, 2168-8184

Cureus Journal Of Medical Science  SPRINGERNATURE

Tipo:
Article
Páginas:
-

Citações Recebidas na Web of Science: 1

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Keywords

  • cushing's disease; hypokalemia; infection; hypercortisolism; cushing?s syndrome

Proyectos asociados

O papel dos microRNA146a e microRNA155 na dor e progressão da osteoartrose.

Investigador Principal: Daniela Santos Oliveira

Estudo Observacional Académico (MicroRNA) . Grünenthal . 2021

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