Cushing's Syndrome Behind Hypokalemia and Severe Infection: A Case Report

Autores da FMUP
Participantes de fora da FMUP
- Elias, C
- Silva, MM
Unidades de investigação
Abstract
Cushing's syndrome (CS) is a rare condition associated with increased morbidity and mortality. Complications derive from hypercortisolism and are mainly cardiovascular, infectious and thrombotic. Most manifestations are unspecific, and the diagnosis is frequently delayed and made only in the setting of complications.We present a woman in whom CS was investigated because of refractory hypokalemia, hypernatremia and metabolic alkalosis. The patient had many cardiovascular risk factors and was admitted to the hospital due to a serious bacterial infection -muscle abscesses evolving into osteomyelitis. The final etiological diagnosis was not possible because the acute event had a fatal outcome.Immunosuppression associated with hypercortisolism makes these patients predisposed to severe infection. Indeed, infectious complications are a relevant cause of death in CS. Diagnosing and treating CS early is paramount in preventing its dismal complications.
Dados da publicação
- ISSN/ISSNe:
- 2168-8184, 2168-8184
- Tipo:
- Article
- Páginas:
- -
- DOI:
- 10.7759/cureus.32486
Cureus Journal Of Medical Science SPRINGERNATURE
Citações Recebidas na Web of Science: 1
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Filiações
Keywords
- cushing's disease; hypokalemia; infection; hypercortisolism; cushing?s syndrome
Proyectos asociados
O papel dos microRNA146a e microRNA155 na dor e progressão da osteoartrose.
Investigador Principal: Daniela Santos Oliveira
Estudo Observacional Académico (MicroRNA) . Grünenthal . 2021
Citar a publicação
Elias C,Oliveira D,Silva MM,Lourenço P. Cushing's Syndrome Behind Hypokalemia and Severe Infection: A Case Report. Cureus J Med Sci. 2022. 14. (12):