Portal de investigação
Effective management of multidrug-resistant HIV with lenacapavir and fostemsavir: A case study
Autores da FMUP
Participantes de fora da FMUP
- Matos F.B.
- Mbanze D.
- Gomes P.
- Figueiredo C.
- Coutinho D.
- Nunes S.
- Azevedo C.
- Fragoso J.
- Teixeira T.
Unidades de investigação
Abstract
Resistance to antiretroviral therapy is an increasing challenge in the management of HIV. We present the case of a woman living with HIV, with a history of multiple treatment regimens and resistances to antiretrovirals, who has been successfully treated with a combination of lenacapavir and fostemsavir for the past year, obtaining an undetectable viral load within one month of starting therapy and reporting no serious side effects. This case is amongst the first to document the combined use of lenacapivir and fostemsavir in treating multidrug-resistant HIV. It supports the potential of these novel agents in managing complex cases of HIV resistance. © The Author(s) 2024.
Dados da publicação
- ISSN/ISSNe:
- 0956-4624, 1758-1052
- Tipo:
- Article
- Páginas:
- -
- Link para outro recurso:
- www.scopus.com
INTERNATIONAL JOURNAL OF STD & AIDS SAGE Publications Ltd
Documentos
- Não há documentos
Filiações
Keywords
- Adult; Anti-HIV Agents; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Middle Aged; Morpholines; Organophosphates; Piperazines; Treatment Outcome; Viral Load; anti human immunodeficiency virus agent; fostemsavir; morpholine derivative; organophosphate; piperazine derivative; adult; case report; combination drug therapy; drug effect; drug therapy; female; human; Human immunodeficiency virus 1; Human immunodeficiency virus infection; middle aged; multidrug resistance; treatment outcome; virus load
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Citar a publicação
Matos FB,Mbanze D,Gomes P,Figueiredo C,Coutinho D,Nunes S,Azevedo C,Fragoso J,Teixeira T,Malheiro L. Effective management of multidrug-resistant HIV with lenacapavir and fostemsavir: A case study. Int. J. STD AIDS. 2024. IF:1,400. (4).
