Trace Elements in Portuguese Children: Urinary Levels and Exposure Predictors

Data de publicação:

Autores da FMUP

  • Cristina Maria Nogueira Da Costa Santos

    Autor

Participantes de fora da FMUP

  • Correia-Sá, L
  • Fernandes, VC
  • Maia, ML
  • Pinto, E
  • Norberto, S
  • Almeida, A
  • Delerue-Matos, C
  • Calhau, C
  • Domingues, VF

Unidades de investigação

Abstract

Exposure to environmental chemicals during developmental stages can result in several adverse outcomes. In this study, the exposure of Portuguese children to Cu, Co, I, Mo, Mn, Ni, As, Sb, Cd, Pb, Sn and Tl was evaluated through the analysis of first morning urine through ICP-MS. Furthermore, we attempted to determine possible exposure predictors. The study sample consisted of 54% girls and 46% boys, with a median age of 10 years; 61% were overweight/obese and were put on a nutritionally oriented diet. For I, half of the population was probably in deficiency status. The median urinary concentrations (mu g/L) were Cu 21.9, Mo 54.6, Co 0.76, Mn 2.1, Ni 4.74, As 37.9, Sb 0.09, Cd 0.29, Pb 0.94, Sn 0.45, Tl 0.39 and I 125.5. The region was a significant predictor for Cu, Co, Ni, As and Tl. Children living in an urban area had higher urinary levels, except for Co and Ni. Age was a significant predictor for Cu, I, Mo, Mn, Ni, Sb, Cd and Sn with urinary levels of these elements decreasing with age. No sex-related differences were observed. Diet and weight group were predictors for urinary Cu, Mn, Ni, Sb and As. Significant differences were observed between the diet/weight groups for Cu, Ni, Sb and As, with the healthy diet group presenting higher values.

Dados da publicação

ISSN/ISSNe:
2305-6304, 2305-6304

Toxics  MDPI AG

Tipo:
Article
Páginas:
-

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Keywords

  • elements; biomonitoring; children; obesity; predictors; urinary levels

Financiamento

Proyectos asociados

COVID-19: Monitorizar e planear com base no risco.

Investigador Principal: Cristina Maria Nogueira da Costa Santos

Estudo Observacional Académico (COVID-19) . 2020

Complexity Sciences applied to Cardiotocography

Investigador Principal: Cristina Maria Nogueira da Costa Santos

Estudo Clínico Académico . 2022

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