Hyperfunctioning papillary thyroid carcinoma - a case report and literature review

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • João Manuel Palmeira Rocha Neves

    Autor

Participantes de fora da FMUP

  • Pereira-Macedo, J
  • Freire, B
  • Macedo-Oliveira, C
  • Mendes, J
  • Carvalho, M
  • Fonseca, S
  • Vinagreiro, M
  • Lemos, R
  • Silva, N
  • Sampaio, F

Unidades de investigação

Abstract

Background Malignant hyperfunctioning thyroid nodules are rare and more likely to occur in follicular cancer types rather than papillary variants. The authors present a case of a papillary thyroid carcinoma associated with a hyperfunctioning nodule. Methods A single adult patient submitted to total thyroidectomy with the presence of thyroid carcinoma within hyperfunctioning nodules was selected. Additionally, brief literature was conducted. Results An asymptomatic 58-year-old male was subjected to routine blood analysis and a TSH level of <0.003 mIU/L was found. Ultrasonography revealed a 21 mm solid, hypoechoic, and heterogenous nodule with microcalcifications in the right lobe. A fine needle aspiration guided by ultrasound resulted in a follicular lesion of undetermined significance. A Tc-99m thyroid scintigram was followed and identified a right-sided hyperfunctioning nodule. Another cytology was performed and a papillary thyroid carcinoma was derived as a result. The patient underwent a total thyroidectomy. Postoperative histology confirmed the diagnosis and a tumor-free margin with no vascular or capsular invasions. Conclusion Hyperfunctioning malignant nodules are a rare association, although a careful approach should be led since major clinical implications arise. Selective fine needle aspiration in all suspicious & GE;1 cm nodules should be considered.

Dados da publicação

ISSN/ISSNe:
0001-5458, 2577-0160

Acta Chirurgica Belgica  Taylor and Francis Ltd.

Tipo:
Review
Páginas:
1-152

Documentos

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Métricas

Filiações mostrar / ocultar

Keywords

  • Thyroid nodule; hyperthyroidism; thyroid tumor; malignant nodule; hot nodule

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