Prediction of movement difficulties at 5 years from parent report at 2 years in children born extremely preterm

Data de publicação: 01/09/2023 Data Ahead of Print: 01/02/2023

Autores da FMUP

José Henrique Dias Pinto De Barros

Autor

Participantes de fora da FMUP

Costa, R
Aubert, AM
Seppänen, AV
Ådén, U
Sarrechia, I
Zemlin, M
Cuttini, M
Männamaa, M
Pierrat, V
van Heijst, A
Zeitlin, J
Johnson, S
SHIPS Res Grp

Unidades de investigação

Ciências da Saúde Pública e Forenses, e Educação Médica

Abstract

AimTo assess the predictive validity of parent-reported gross motor impairment (GMI) at age 2 years to detect significant movement difficulties at age 5 years in children born extremely preterm. MethodData were from 556 children (270 males, 286 females) born at less than 28 weeks' gestation in 2011 to 2012 in 10 European countries. Parent report of moderate/severe GMI was defined as walking unsteadily or unable to walk unassisted at 2 years corrected age. Examiners assessed significant movement difficulties (score <= 5th centile on the Movement Assessment Battery for Children, Second Edition) and diagnoses of cerebral palsy (CP) were collected by parent report at 5 years chronological age. ResultsAt 2 years, 66 (11.9%) children had moderate/severe GMI. At 5 years, 212 (38.1%) had significant movement difficulties. Parent reports of GMI at age 2 years accurately classified CP at age 5 years in 91.0% to 93.2% of children. Classification of moderate/severe GMI at age 2 years had high specificity (96.2%; 95% confidence interval 93.6-98.0) and positive predictive value (80.3%; 68.7-89.1) for significant movement difficulties at age 5 years. However, 74.5% of children with significant movement difficulties at 5 years were not identified with moderate/severe GMI at age 2 years, resulting in low sensitivity (25.1%; 19.4-31.5). InterpretationThis questionnaire may be used to identify children born extremely preterm who at age 2 years have a diagnosis of CP or movement difficulties that are likely to have a significant impact on their functional outcomes at age 5 years.

Dados da publicação

ISSN/ISSNe:: 1469-8749, 0012-1622
Tipo:: Article
Páginas:: 1215-1225
DOI:: 10.1111/dmcn.15518

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Métricas

Filiações

Costa, R:: Univ Porto, EPIUnit, Inst Saude Publ, Porto, Portugal

Lab Invest Integrat & Translac Saude Populac ITR, Porto, Portugal
Aubert, AM:: Univ Paris Cite, Ctr Res Epidemiol & Stat CRESS, Obstetr Perinatal & Pediat Epidemiol Res Team, Inserm,EPOPe,INRAE, Paris, France
Seppänen, AV:: Univ Paris Cite, Ctr Res Epidemiol & Stat CRESS, Obstetr Perinatal & Pediat Epidemiol Res Team, Inserm,EPOPe,INRAE, Paris, France
Ådén, U:: Karolinska Inst, Dept Womens & Childrens Hlth, Stockholm, Sweden

Karolinska Univ Hosp, Dept Neonatal Med, Stockholm, Sweden
Sarrechia, I:: Univ Antwerp, Fac Med & Hlth Sci, Dept Med & Populat Hlth, Antwerp, Belgium
Zemlin, M:: Saarland Univ, Dept Gen Pediat & Neonatol, Med Ctr, Homburg, Germany
Cuttini, M:: Bambino Gesu Pediat Hosp, Clin Care & Management Innovat Res Area, Rome, Italy
Männamaa, M:: Univ Tartu, Inst Clin Med, Dept Paediat, Tartu, Estonia
Pierrat, V:: Univ Paris Cite, Ctr Res Epidemiol & Stat CRESS, Obstetr Perinatal & Pediat Epidemiol Res Team, Inserm,EPOPe,INRAE, Paris, France

Jeanne Flandre Hosp, CHU Lille, Dept Neonatal Med, Lille, France
van Heijst, A:: Radboud Univ Nijmegen, Dept Neonatol, Med Ctr, Nijmegen, Netherlands

Erasmus MC, Rotterdam, Netherlands
Barros, H:: Univ Porto, EPIUnit, Inst Saude Publ, Porto, Portugal

Lab Invest Integrat & Translac Saude Populac ITR, Porto, Portugal
Zeitlin, J:: Univ Paris Cite, Ctr Res Epidemiol & Stat CRESS, Obstetr Perinatal & Pediat Epidemiol Res Team, Inserm,EPOPe,INRAE, Paris, France
Johnson, S:: Univ Leicester, Dept Populat Hlth Sci, Leicester, England