Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • Bernardo Manuel De Sousa Pinto

    Autor

  • Jorge Filipe Miranda Rodrigues

    Autor

  • João De Almeida Lopes Da Fonseca

    Autor

Participantes de fora da FMUP

  • Louis, R
  • Giuliano, AFM
  • Baiardini, I
  • Braido, F
  • Czarlewski, W
  • Bedbrook, A
  • Haahtela, T
  • Valiulis, A
  • Brussino, L
  • Cecchi, L
  • Cruz, AA
  • Gemicioglu, B
  • Fokkens, WJ
  • Ivancevich, JC
  • Klimek, L
  • Kraxner, H
  • Kuna, P
  • Kupczyk, M
  • Kvedariene, V
  • Larenas-Linnemann, D
  • Louis, R
  • Nadif, R
  • Niedoszytko, M
  • Okamoto, Y
  • Ollert, M
  • Papadopoulos, NG
  • Patella, V
  • Pawankar, R
  • Pham-Thi, N
  • Pfaar, O
  • Regateiro, FS
  • Roche, N
  • Rouadi, PW
  • Samolinski, B
  • Sastre, J
  • Savoure, M
  • Scichilone, N
  • Sheikh, A
  • Taborda-Barata, L
  • ToPPila-Salmi, S
  • Yorgancioglu, A
  • Zidarn, M
  • Anto, JM
  • Zuberbier, T
  • Canonica, GW
  • Ventura, MT
  • Petre, B
  • Bousquet, J

Unidades de investigação

Abstract

BACKGROUND: EQ-5D-5L (EuroQOL, 5 Domains, 5 Levels) is a widely used health-related quality-of-life instrument, comprising 5 domains. However, it is not known how each domain is impacted by rhinitis or asthma control. OBJECTIVE: To assess the association between rhinitis or asthma control and the different EQ-5D-5L domains using data from the MASK-air mHealth app. METHODS: In this cross-sectional study, we assessed data from all MASK-air users (2015-2021; 24 countries). For the levels of each EQ-5D-5L domain, we assessed rhinitis and asthma visual analog scales (VASs) and the combined symptom-medication score (CSMS). We built ordinal multivariable models assessing the adjusted association between VAS/CSMS values and the levels of each EQ-5D-5L domain. Finally, we compared EQ-5D-5L data from users with rhinitis and self-reported asthma with data from users with rhinitis alone. RESULTS: We assessed 5354 days from 3092 users. We observed an association between worse control of rhinitis or asthma (higher VASs and CSMS) and worse EQ-5D-5L levels. In multivariable models, all VASs and the CSMS were associated with higher levels of pain/discomfort and daily activities. For anxiety/depression, the association was mostly observed for rhinitis-related tools (VAS nose, VAS global, and CSMS), although the presence of self-reported asthma was also associated with worse anxiety/depression. Worse mobility ("walking around") was particularly associated with VAS asthma and with the presence of asthma.CONCLUSIONS: A worse rhinitis control and a worse asthma control are associated with higher EQ-5D-5L levels, particularly regarding pain/discomfort and activity impairment. Worse rhinitis control is associated with worse anxiety/depression, and poor asthma control with worse mobility. (c) 2023 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2023;11:3742-51)

Copyright © 2023 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Dados da publicação

ISSN/ISSNe:
2213-2198, 2213-2201

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE  Elsevier

Tipo:
Article
Páginas:
3742-37519
Link para outro recurso:
www.scopus.com

Citações Recebidas na Scopus: 7

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Keywords

  • Allergic rhinitis; Asthma; Mobile health; Quality of life

Financiamento

Proyectos asociados

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Clinical Research Collaboration Severe Heterogenous Asthma Research collaboration, Patient-centered (CRC SHARP).

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