Portal de investigação
Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study
Data de publicação:
Data Ahead of Print:
Autores da FMUP
Participantes de fora da FMUP
- Louis, R
- Giuliano, AFM
- Baiardini, I
- Braido, F
- Czarlewski, W
- Bedbrook, A
- Haahtela, T
- Valiulis, A
- Brussino, L
- Cecchi, L
- Cruz, AA
- Gemicioglu, B
- Fokkens, WJ
- Ivancevich, JC
- Klimek, L
- Kraxner, H
- Kuna, P
- Kupczyk, M
- Kvedariene, V
- Larenas-Linnemann, D
- Louis, R
- Nadif, R
- Niedoszytko, M
- Okamoto, Y
- Ollert, M
- Papadopoulos, NG
- Patella, V
- Pawankar, R
- Pham-Thi, N
- Pfaar, O
- Regateiro, FS
- Roche, N
- Rouadi, PW
- Samolinski, B
- Sastre, J
- Savoure, M
- Scichilone, N
- Sheikh, A
- Taborda-Barata, L
- ToPPila-Salmi, S
- Yorgancioglu, A
- Zidarn, M
- Anto, JM
- Zuberbier, T
- Canonica, GW
- Ventura, MT
- Petre, B
- Bousquet, J
Unidades de investigação
Abstract
BACKGROUND: EQ-5D-5L (EuroQOL, 5 Domains, 5 Levels) is a widely used health-related quality-of-life instrument, comprising 5 domains. However, it is not known how each domain is impacted by rhinitis or asthma control. OBJECTIVE: To assess the association between rhinitis or asthma control and the different EQ-5D-5L domains using data from the MASK-air mHealth app. METHODS: In this cross-sectional study, we assessed data from all MASK-air users (2015-2021; 24 countries). For the levels of each EQ-5D-5L domain, we assessed rhinitis and asthma visual analog scales (VASs) and the combined symptom-medication score (CSMS). We built ordinal multivariable models assessing the adjusted association between VAS/CSMS values and the levels of each EQ-5D-5L domain. Finally, we compared EQ-5D-5L data from users with rhinitis and self-reported asthma with data from users with rhinitis alone. RESULTS: We assessed 5354 days from 3092 users. We observed an association between worse control of rhinitis or asthma (higher VASs and CSMS) and worse EQ-5D-5L levels. In multivariable models, all VASs and the CSMS were associated with higher levels of pain/discomfort and daily activities. For anxiety/depression, the association was mostly observed for rhinitis-related tools (VAS nose, VAS global, and CSMS), although the presence of self-reported asthma was also associated with worse anxiety/depression. Worse mobility ("walking around") was particularly associated with VAS asthma and with the presence of asthma.CONCLUSIONS: A worse rhinitis control and a worse asthma control are associated with higher EQ-5D-5L levels, particularly regarding pain/discomfort and activity impairment. Worse rhinitis control is associated with worse anxiety/depression, and poor asthma control with worse mobility. (c) 2023 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2023;11:3742-51)
Copyright © 2023 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.
Dados da publicação
- ISSN/ISSNe:
- 2213-2198, 2213-2201
- Tipo:
- Article
- Páginas:
- 3742-37519
- Link para outro recurso:
- www.scopus.com
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE Elsevier
Citações Recebidas na Scopus: 7
Documentos
- Não há documentos
Filiações
Keywords
- Allergic rhinitis; Asthma; Mobile health; Quality of life
Campos de estudo
Financiamento
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Citar a publicação
Sousa B,Louis R,Rodrigues J,Giuliano A,Baiardini I,Braido F,Czarlewski W,Bedbrook A,Haahtela T,Valiulis A,Brussino L,Cecchi L,Cruz AA,Gemicioglu B,Fokkens WJ,Ivancevich JC,Klimek L,Kraxner H,Kuna P,Kupczyk M,Kvedariene V,Larenas D,Louis R,Nadif R,Niedoszytko M,Okamoto Y,Ollert M,Papadopoulos NG,Patella V,Pawankar R,Pham N,Pfaar O,Regateiro FS,Roche N,Rouadi PW,Samolinski B,Sastre J,Savoure M,Scichilone N,Sheikh A,Taborda L,ToPPila S,Yorgancioglu A,Zidarn M,Anto JM,Zuberbier T,Canonica GW,Ventura MT,Fonseca JA,Petre B,Bousquet J. Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study. J. Allergy Clin. Immunol. Pract. 2023. 11. (12):p. 3742-37519. IF:9,400. (1).
