Portal de investigação
Impairment of EQ-5D-5L Domains According to Allergic Rhinitis and Asthma Control: A MASK-air Real-World Study
Data de publicação:
Data Ahead of Print:
Autores da FMUP
Participantes de fora da FMUP
- Louis, R
- Giuliano, AFM
- Baiardini, I
- Braido, F
- Czarlewski, W
- Bedbrook, A
- Haahtela, T
- Valiulis, A
- Brussino, L
- Cecchi, L
- Cruz, AA
- Gemicioglu, B
- Fokkens, WJ
- Ivancevich, JC
- Klimek, L
- Kraxner, H
- Kuna, P
- Kupczyk, M
- Kvedariene, V
- Larenas-Linnemann, D
- Louis, R
- Nadif, R
- Niedoszytko, M
- Okamoto, Y
- Ollert, M
- Papadopoulos, NG
- Patella, V
- Pawankar, R
- Pham-Thi, N
- Pfaar, O
- Regateiro, FS
- Roche, N
- Rouadi, PW
- Samolinski, B
- Sastre, J
- Savoure, M
- Scichilone, N
- Sheikh, A
- Taborda-Barata, L
- ToPPila-Salmi, S
- Yorgancioglu, A
- Zidarn, M
- Anto, JM
- Zuberbier, T
- Canonica, GW
- Ventura, MT
- Petre, B
- Bousquet, J
Unidades de investigação
Abstract
BACKGROUND: EQ-5D-5L (EuroQOL, 5 Domains, 5 Levels) is a widely used health-related quality-of-life instrument, comprising 5 domains. However, it is not known how each domain is impacted by rhinitis or asthma control. OBJECTIVE: To assess the association between rhinitis or asthma control and the different EQ-5D-5L domains using data from the MASK-air mHealth app. METHODS: In this cross-sectional study, we assessed data from all MASK-air users (2015-2021; 24 countries). For the levels of each EQ-5D-5L domain, we assessed rhinitis and asthma visual analog scales (VASs) and the combined symptom-medication score (CSMS). We built ordinal multivariable models assessing the adjusted association between VAS/CSMS values and the levels of each EQ-5D-5L domain. Finally, we compared EQ-5D-5L data from users with rhinitis and self-reported asthma with data from users with rhinitis alone. RESULTS: We assessed 5354 days from 3092 users. We observed an association between worse control of rhinitis or asthma (higher VASs and CSMS) and worse EQ-5D-5L levels. In multivariable models, all VASs and the CSMS were associated with higher levels of pain/discomfort and daily activities. For anxiety/depression, the association was mostly observed for rhinitis-related tools (VAS nose, VAS global, and CSMS), although the presence of self-reported asthma was also associated with worse anxiety/depression. Worse mobility ("walking around") was particularly associated with VAS asthma and with the presence of asthma.CONCLUSIONS: A worse rhinitis control and a worse asthma control are associated with higher EQ-5D-5L levels, particularly regarding pain/discomfort and activity impairment. Worse rhinitis control is associated with worse anxiety/depression, and poor asthma control with worse mobility. (c) 2023 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2023;11:3742-51)
Copyright © 2023 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.
Dados da publicação
- ISSN/ISSNe:
- 2213-2198, 2213-2201
- Tipo:
- Article
- Páginas:
- 3742-37519
- PubMed:
- 37572753
- Link para outro recurso:
- www.scopus.com
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE Elsevier
Citações Recebidas na Scopus: 7
Documentos
- Não há documentos
Filiações
Keywords
- Allergic rhinitis; Asthma; Mobile health; Quality of life
Financiamento
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