Available and affordable complementary treatments for COVID-19: From hypothesis to pilot studies and the need for implementation

Autores da FMUP
Participantes de fora da FMUP
- Bousquet, J
- Haahtela, T
- Blain, H
- Czarlewski, W
- Zuberbier, T
- Bedbrook, A
- Cruz, AA
- Klimek, L
- Kuna, P
- Samolinski, B
- Valiulis, A
- Lemaire, A
- Anto, JM
Unidades de investigação
Abstract
Vaccination is a highly effective preventive measure against COVID-19. However, complementary treatments are needed to better control the disease. Fermented vegetables and spices, agonists of the antioxidant transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and TRPA1/V1 channels (Transient Receptor Potential Ankyrin 1 and Vanillin 1), may help in the control of COVID-19. Some preliminary clinical trials suggest that curcumin (spice) can prevent some of the COVID-19 symptoms. Before any conclusion can be drawn and these treatments recommended for COVID-19, the data warrant confirmation. In particular, the benefits of the foods need to be assessed in more patients, through research studies and large trials employing a double-blind, placebo-controlled design.
© 2022 The Authors. Clinical and Translational Allergy published by John Wiley & Sons Ltd on behalf of European Academy of Allergy and Clinical Immunology.
Dados da publicação
- ISSN/ISSNe:
- 2045-7022, 2045-7022
- Tipo:
- Article
- Páginas:
- -
- DOI:
- 10.1002/clt2.12127
- Link para outro recurso:
- www.scopus.com
Clinical and Translational Allergy John Wiley & Sons Inc.
Citações Recebidas na Web of Science: 5
Citações Recebidas na Scopus: 5
Documentos
- Não há documentos
Filiações
Keywords
- broccoli; COVID-19; curcumin; Nrf2; TRP channel
Campos de estudo
Financiamento
Proyectos asociados
Prevalence and Characterisation of Asthma Patients According to Disease Severity in Portugal (EPI-ASTHMA) - NCT05169619
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Clínico Observacional (EPI-ASTHMA) . AstraZeneca . 2021
Effect of a Mobile App on Improving Asthma Control in Adolescents and Adults With Persistent Asthma: A Pilot Randomized Multicentre, Superiority Clinical Trial (mINSPIRERS) - NCT05129527
Investigador Principal: João de Almeida Lopes da Fonseca
Ensaio Clínico Académico (mINSPIRERS) . 2021
Utilização em estudos observacionais do Registo de Asma Grave Portugal.
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Observacional Académico (RAG) . 2020
Clinical Research Collaboration Severe Heterogenous Asthma Research collaboration, Patient-centered (CRC SHARP).
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Clínico Observacional (SHARP) . European Respiratory Society . 2021
Use of secondary data, health technology assessment methods and economic modelling applied to penicillin allergy
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Clínico Académico . 2020
Using different data sources for the identification of asthma patients and those at high risk of adverse outcomes
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Clínico Académico . 2020
Phenotypes of Chronic Diseases of the Airways: Towards Multidimensional Data -Driven Profiling
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Clínico Académico . 2020
Citar a publicação
Bousquet J,Haahtela T,Blain H,Czarlewski W,Zuberbier T,Bedbrook A,Cruz AA,Fonseca J,Klimek L,Kuna P,Samolinski B,Valiulis A,Lemaire A,Anto JM. Available and affordable complementary treatments for COVID-19: From hypothesis to pilot studies and the need for implementation. Clin. Transl. Allergy. 2022. 12. (3):e12127. IF:4,400. (2).