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Management of anaphylaxis due to COVID-19 vaccines in the elderly

Data de publicação:

Autores da FMUP

  • João De Almeida Lopes Da Fonseca

    Autor

  • Bernardo Manuel De Sousa Pinto

    Autor

Participantes de fora da FMUP

  • Bousquet, J
  • Agache, I
  • Blain, H
  • Jutel, M
  • Ventura, MT
  • Worm, M
  • Del Giacco, S
  • Benetos, A
  • Bilo, BM
  • Czarlewski, W
  • Latiff, AHA
  • Al-Ahmad, M
  • Angier, E
  • Annesi-Maesano, I
  • Atanaskovic-Markovic, M
  • Bachert, C
  • Barbaud, A
  • Bedbrook, A
  • Bennoor, KS
  • Berghea, EC
  • Bindslev-Jensen, C
  • Bonini, S
  • Bosnic-Anticevich, S
  • Brockow, K
  • Brussino, L
  • Camargos, P
  • Canonica, GW
  • Cardona, V
  • Carreiro-Martins, P
  • Carriazo, A
  • Casale, T
  • Caubet, JC
  • Cecchi, L
  • Cherubini, A
  • Christoff, G
  • Chu, DRK
  • Cruz, AA
  • Dokic, D
  • El-Gamal, Y
  • Ebisawa, M
  • Eberlein, B
  • Farrell, J
  • Fernandez-Rivas, M
  • Fokkens, WJ
  • Gao, YD
  • Gavazzi, G
  • Gawlik, R
  • Gelincik, A
  • Gemicioglu, B
  • Gotua, M
  • Guérin, O
  • Haahtela, T
  • Hoffmann-Sommergruber, K
  • Hoffmann, HJ
  • Hofmann, M
  • Hrubisko, M
  • Illario, M
  • Irani, C
  • Ispayeva, Z
  • Ivancevich, JC
  • Julge, K
  • Kaidashev, I
  • Khaitov, M
  • Knol, E
  • Kraxner, H
  • Kuna, P
  • Kvedariene, V
  • Lauerma, A
  • Le, LTT
  • Le Moing, V
  • Levin, M
  • Louis, R
  • Lourenco, O
  • Mahler, V
  • Martin, FC
  • Matucci, A
  • Milenkovic, B
  • Miot, S
  • Montella, E
  • Morais-Almeida, M
  • Mortz, CG
  • Mullol, J
  • Namazova-Baranova, L
  • Neffen, H
  • Nekam, K
  • Niedoszytko, M
  • Odemyr, M
  • O'Hehir, RE
  • Okamoto, Y
  • Ollert, M
  • Palomares, O
  • Papadopoulos, NG
  • Panzner, P
  • Passalacqua, G
  • Patella, V
  • Petrovic, M
  • Pfaar, O
  • Pham-Thi, N
  • Plavec, D
  • Popov, TA
  • Recto, MT
  • Regateiro, FS
  • Reynes, J
  • Roller-Winsberger, RE
  • Rolland, Y
  • Romano, A
  • Rondon, C
  • Rottem, M
  • Rouadi, PW
  • Salles, N
  • Samolinski, B
  • Santos, AF
  • Sarquis, FS
  • Sastre, J
  • Schols, JMGA
  • Scichilone, N
  • Sediva, A
  • Shamji, MH
  • Sheikh, A
  • Skypala, I
  • Smolinska, S
  • Sokolowska, M
  • Sova, M
  • Stelmach, R
  • Sturm, G
  • Ulrik, CS
  • Todo-Bom, AM
  • Toppila-Salmi, S
  • Tsiligianni, I
  • Torres, M
  • Untersmayr, E
  • Pereira, MU
  • Valiulis, A
  • Vitte, J
  • Vultaggio, A
  • Wallace, D
  • Walusiak-Skorupa, J
  • Wang, DY
  • Waserman, S
  • Yorgancioglu, A
  • Yusuf, OM
  • Zernotti, M
  • Zidarn, M
  • Chivato, T
  • Akdis, CA
  • Zuberbier, T
  • Klimek, L

Unidades de investigação

Abstract

Older adults, especially men and/or those with diabetes, hypertension, and/or obesity, are prone to severe COVID-19. In some countries, older adults, particularly those residing in nursing homes, have been prioritized to receive COVID-19 vaccines due to high risk of death. In very rare instances, the COVID-19 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered carefully. An ARIA-EAACI-EuGMS (Allergic Rhinitis and its Impact on Asthma, European Academy of Allergy and Clinical Immunology, and European Geriatric Medicine Society) Working Group has proposed some recommendations for older adults receiving the COVID-19 vaccines. Anaphylaxis to COVID-19 vaccines is extremely rare (from 1 per 100,000 to 5 per million injections). Symptoms are similar in younger and older adults but they tend to be more severe in the older patients. Adrenaline is the mainstay treatment and should be readily available. A flowchart is proposed to manage anaphylaxis in the older patients.

© 2021 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

Dados da publicação

ISSN/ISSNe:
0105-4538, 1398-9995

ALLERGY  Wiley-Blackwell Publishing Ltd

Tipo:
Article
Páginas:
2952-2964
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 15

Citações Recebidas na Scopus: 15

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Keywords

  • adrenaline; anaphylaxis; COVID-19 vaccines; older (adults; people)

Campos de estudo

Proyectos asociados

Prevalence and Characterisation of Asthma Patients According to Disease Severity in Portugal (EPI-ASTHMA) - NCT05169619

Investigador Principal: João de Almeida Lopes da Fonseca

Estudo Clínico Observacional (EPI-ASTHMA) . AstraZeneca . 2021

Utilização em estudos observacionais do Registo de Asma Grave Portugal.

Investigador Principal: João de Almeida Lopes da Fonseca

Estudo Observacional Académico (RAG) . 2020

Clinical Research Collaboration Severe Heterogenous Asthma Research collaboration, Patient-centered (CRC SHARP).

Investigador Principal: João de Almeida Lopes da Fonseca

Estudo Clínico Observacional (SHARP) . European Respiratory Society . 2021

Seroprevalence of SARS-CoV-2 and assessment of epidemiologic determinants in Portuguese municipal workers

Investigador Principal: Bernardo Manuel De Sousa Pinto

Estudo Clínico Académico (SARS-CoV-2) . 2021

Use of secondary data, health technology assessment methods and economic modelling applied to penicillin allergy

Investigador Principal: João de Almeida Lopes da Fonseca

Estudo Clínico Académico . 2020

Using different data sources for the identification of asthma patients and those at high risk of adverse outcomes

Investigador Principal: João de Almeida Lopes da Fonseca

Estudo Clínico Académico . 2020

Phenotypes of Chronic Diseases of the Airways: Towards Multidimensional Data -Driven Profiling

Investigador Principal: João de Almeida Lopes da Fonseca

Estudo Clínico Académico . 2020

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