Monitoring Adherence to Asthma Inhalers Using the InspirerMundi App: Analysis of Real-World, Medium-Term Feasibility Studies

Autores da FMUP
Participantes de fora da FMUP
- Mendes, S
- Alves-Correia, M
- Ferreira, JA
- Lopes, I
- Gomes, J
- Couto, M
- Loureiro, CC
- Santos, LM
- Arrobas, A
- Valério, M
- Bom, AT
- Azevedo, J
- Teixeira, MF
- Ferreira-Magalh?es, M
- Pinto, PL
- Pinto, N
- Neves, AC
- Mor?te, A
- Bom, FT
- Costa, A
- Vasconcelos, MJ
- Falcao, H
- Marques, ML
- Mendes, A
- Cardoso, J
- Rodrigues, JCC
- Oliveira, G
- Carvalho, J
- Lozoya, C
- Santos, N
- Menezes, F
- Gomes, R
- C?mara, R
- Alves, RR
- Moreira, AS
- Abreu, C
- Silva, R
- Alves, C
- Lopes, C
- Taborda-Barata, L
- Fernandes, RM
- Ferreira, R
- Chaves-Loureiro, C
- Cálix, MJ
- Alves, A
Unidades de investigação
Abstract
Background: Poor medication adherence is a major challenge in asthma and objective assessment of inhaler adherence is needed. InspirerMundi app aims to monitor inhaler adherence while turning it into a positive experience through gamification and social support.Objective: We assessed the medium-term feasibility of the InspirerMundi app to monitor inhaler adherence in real-world patients with persistent asthma (treated with daily inhaled medication). In addition, we attempted to identify the characteristics of the patients related to higher app use.Methods: Two real-world multicenter observational studies, with one initial face-to-face visit and a 4-month telephone interview, were conducted in 29 secondary care centers from Portugal. During an initial face-to-face visit, patients were invited to use the app daily to register their asthma medication intakes. A scheduled intake was considered taken when patients took a photo of the medication (inhaler, blister, or others) using the image-based medication detection tool. Medication adherence was calculated as the number of doses taken as a percentage of the number scheduled. Interacting with the app =30 days was used as the cut-off for higher app use.Results: A total of 114 patients {median 20 [percentile 25 to percentile 75 (P25-P75) 16-36] years, 62% adults} were invited, 107 (94%) installed the app and 83 (73%) completed the 4-month interview. Patients interacted with the app for a median of 18 [3-45] days, translated on a median use rate of 15 [3-38]%. Median inhaler adherence assessed through the app was 34 [4-73]% when considering all scheduled inhalations for the study period. Inhaler adherence assessed was not significantly correlated with self-reported estimates. Median adherence for oral and other medication was 41 [6-83]% and 43 [3-73]%, respectively. Patients with higher app use were slightly older (p = 0.012), more frequently taking medication for other health conditions (p = 0.040), and more frequently prescribed long-acting muscarinic antagonists (LAMA, p = 0.024). After 4 months, Control of Allergic Rhinitis and Asthma Test (CARAT) scores improved (p < 0.001), but no differences between patients interacting with the app for 30 days or less were seen.Conclusions: The InspirerMundi app was feasible to monitor inhaler adherence in patients with persistent asthma. The persistent use of this mHealth technology varies widely. A better understanding of characteristics related to higher app use is still needed before effectiveness studies are undertaken.
Copyright © 2021 Jácome, Almeida, Pereira, Amaral, Vieira-Marques, Mendes, Alves-Correia, Ferreira, Lopes, Gomes, Araújo, Couto, Chaves Loureiro, Santos, Arrobas, Valério, Todo Bom, Azevedo, Teixeira, Ferreira-Magalhães, Pinto, Pinto, Neves, Morête, Bom, Costa, Silva, Vasconcelos, Falcão, Marques, Mendes, Cardoso, Cidrais Rodrigues, Oliveira, Carvalho, Lozoya, Santos, Menezes, Gomes, Câmara, Alves, Moreira, Abreu, Silva, Bordalo, Alves, Lopes, Taborda-Barata, Fernandes, Ferreira, Chaves-Loureiro, Cálix, Alves and Fonseca.
Dados da publicação
- ISSN/ISSNe:
- 2673-3129, 2673-3129
- Tipo:
- Article
- Páginas:
- 649506-649506
- PubMed:
- 35047915
- Link para outro recurso:
- www.scopus.com
Frontiers In Medical Technology FRONTIERS MEDIA SA
Citações Recebidas na Web of Science: 5
Citações Recebidas na Scopus: 7
Documentos
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Filiações
Keywords
- mHealth; smartphone; technology assessment; medication adherence; self-management; patient participation
Financiamento
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