Monitoring Adherence to Asthma Inhalers Using the InspirerMundi App: Analysis of Real-World, Medium-Term Feasibility Studies

Autores da FMUP
Participantes de fora da FMUP
- Mendes, S
- Alves-Correia, M
- Ferreira, JA
- Lopes, I
- Gomes, J
- Couto, M
- Loureiro, CC
- Santos, LM
- Arrobas, A
- Valério, M
- Bom, AT
- Azevedo, J
- Teixeira, MF
- Ferreira-Magalh?es, M
- Pinto, PL
- Pinto, N
- Neves, AC
- Mor?te, A
- Bom, FT
- Costa, A
- Vasconcelos, MJ
- Falcao, H
- Marques, ML
- Mendes, A
- Cardoso, J
- Rodrigues, JCC
- Oliveira, G
- Carvalho, J
- Lozoya, C
- Santos, N
- Menezes, F
- Gomes, R
- C?mara, R
- Alves, RR
- Moreira, AS
- Abreu, C
- Silva, R
- Alves, C
- Lopes, C
- Taborda-Barata, L
- Fernandes, RM
- Ferreira, R
- Chaves-Loureiro, C
- Cálix, MJ
- Alves, A
Unidades de investigação
Abstract
Background: Poor medication adherence is a major challenge in asthma and objective assessment of inhaler adherence is needed. InspirerMundi app aims to monitor inhaler adherence while turning it into a positive experience through gamification and social support.Objective: We assessed the medium-term feasibility of the InspirerMundi app to monitor inhaler adherence in real-world patients with persistent asthma (treated with daily inhaled medication). In addition, we attempted to identify the characteristics of the patients related to higher app use.Methods: Two real-world multicenter observational studies, with one initial face-to-face visit and a 4-month telephone interview, were conducted in 29 secondary care centers from Portugal. During an initial face-to-face visit, patients were invited to use the app daily to register their asthma medication intakes. A scheduled intake was considered taken when patients took a photo of the medication (inhaler, blister, or others) using the image-based medication detection tool. Medication adherence was calculated as the number of doses taken as a percentage of the number scheduled. Interacting with the app =30 days was used as the cut-off for higher app use.Results: A total of 114 patients {median 20 [percentile 25 to percentile 75 (P25-P75) 16-36] years, 62% adults} were invited, 107 (94%) installed the app and 83 (73%) completed the 4-month interview. Patients interacted with the app for a median of 18 [3-45] days, translated on a median use rate of 15 [3-38]%. Median inhaler adherence assessed through the app was 34 [4-73]% when considering all scheduled inhalations for the study period. Inhaler adherence assessed was not significantly correlated with self-reported estimates. Median adherence for oral and other medication was 41 [6-83]% and 43 [3-73]%, respectively. Patients with higher app use were slightly older (p = 0.012), more frequently taking medication for other health conditions (p = 0.040), and more frequently prescribed long-acting muscarinic antagonists (LAMA, p = 0.024). After 4 months, Control of Allergic Rhinitis and Asthma Test (CARAT) scores improved (p < 0.001), but no differences between patients interacting with the app for 30 days or less were seen.Conclusions: The InspirerMundi app was feasible to monitor inhaler adherence in patients with persistent asthma. The persistent use of this mHealth technology varies widely. A better understanding of characteristics related to higher app use is still needed before effectiveness studies are undertaken.
Copyright © 2021 Jácome, Almeida, Pereira, Amaral, Vieira-Marques, Mendes, Alves-Correia, Ferreira, Lopes, Gomes, Araújo, Couto, Chaves Loureiro, Santos, Arrobas, Valério, Todo Bom, Azevedo, Teixeira, Ferreira-Magalhães, Pinto, Pinto, Neves, Morête, Bom, Costa, Silva, Vasconcelos, Falcão, Marques, Mendes, Cardoso, Cidrais Rodrigues, Oliveira, Carvalho, Lozoya, Santos, Menezes, Gomes, Câmara, Alves, Moreira, Abreu, Silva, Bordalo, Alves, Lopes, Taborda-Barata, Fernandes, Ferreira, Chaves-Loureiro, Cálix, Alves and Fonseca.
Dados da publicação
- ISSN/ISSNe:
- 2673-3129, 2673-3129
- Tipo:
- Article
- Páginas:
- 649506-649506
- Link para outro recurso:
- www.scopus.com
Frontiers In Medical Technology FRONTIERS MEDIA SA
Citações Recebidas na Web of Science: 5
Citações Recebidas na Scopus: 7
Documentos
- Não há documentos
Filiações
Keywords
- mHealth; smartphone; technology assessment; medication adherence; self-management; patient participation
Financiamento
Proyectos asociados
Prevalence and Characterisation of Asthma Patients According to Disease Severity in Portugal (EPI-ASTHMA) - NCT05169619
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Clínico Observacional (EPI-ASTHMA) . AstraZeneca . 2021
Utilização em estudos observacionais do Registo de Asma Grave Portugal.
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Observacional Académico (RAG) . 2020
Use of secondary data, health technology assessment methods and economic modelling applied to penicillin allergy
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Clínico Académico . 2020
Using different data sources for the identification of asthma patients and those at high risk of adverse outcomes
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Clínico Académico . 2020
Phenotypes of Chronic Diseases of the Airways: Towards Multidimensional Data -Driven Profiling
Investigador Principal: João de Almeida Lopes da Fonseca
Estudo Clínico Académico . 2020
Citar a publicação
Jácome C,Almeida R,Pereira AM,Amaral R,Vieira P,Mendes S,Alves M,Ferreira JA,Lopes I,Gomes J,Araújo L,Couto M,Loureiro CC,Santos LM,Arrobas A,Valério M,Bom AT,Azevedo J,Teixeira MF,Ferreira M,Pinto PL,Pinto N,Neves AC,Mor?te A,Bom FT,Costa A,Silva D,Vasconcelos MJ,Falcao H,Marques ML,Mendes A,Cardoso J,Rodrigues JCC,Oliveira G,Carvalho J,Lozoya C,Santos N,Menezes F,Gomes R,C?mara R,Alves RR,Moreira AS,Abreu C,Silva R,Bordalo D,Alves C,Lopes C,Taborda L,Fernandes RM,Ferreira R,Chaves C,Cálix MJ,Alves A,Fonseca JA. Monitoring Adherence to Asthma Inhalers Using the InspirerMundi App: Analysis of Real-World, Medium-Term Feasibility Studies. Front. Med. Technol. 2021. 3. p. 649506-649506.