Nationwide Analysis of Intact Abdominal Aortic Aneurysm Repair in Portugal from 2000 to 2015

Autores da FMUP

• Marina Felicidade Dias Neto

  Autor

• Joaquim Adelino Correia Ferreira Leite Moreira

  Autor

• José Alberto Da Silva Freitas

  Autor

Participantes de fora da FMUP

• Mani, K
• Sampaio, S.

Unidades de investigação

• Cirurgia e Fisiologia

• Medicina da Comunidade, Informação e Decisão em Saúde

• RISE-Health

  

  Investigador

  Fernando Carlos De Landér Schmitt

Abstract

Background: Results on the management of infrarenal abdominal aortic aneurysm (AAA) from Mediterranean countries are scarce. The aim of this study was to evaluate trends in rate of and mortality after repair of intact AAA (iAAA) in Portugal. Methods: iAAA repairs registered in the hospitals' administrative database of the National Health Service from 2000 to 2015 were retrospectively analyzed regarding demographics (age and gender) and type of repair (open surgery [OS] or endovascular repair [EVAR]). Rate and mortality were compared among three time periods: 2000-2004, 2005-2009, and 2010-2015. Results: Age-standardized rate of iAAA repair increased consistently across the time periods under analysis from 3.6 +/- 0.6/100,000/year in 2000-2004, to 5.6 +/- 0.4/100,000/year in 2005-2009 and to 7.1 +/- 0.9/100,000/year in 2010-2015 (P < 0.001). The percentage of EVAR among all iAAA repairs rose steeply from 0 to 21 +/- 19% and then to 58 +/- 7% (P < 0.001). The rate of OS also increased from the first to the second period, but there was a decrease in the third period (P < 0.001). The in-hospital mortality after iAAA repair decreased from 7.5 +/- 1.3% to 6.6 +/- 1.6% and then to 5.1 +/- 1.9% (P < 0.001). This variation corresponded to a decrease in in-hospital mortality after EVAR (from 4.0 +/- 3.5% to 2.8 +/- 0.9%, P < 0.001) and increased in-hospital mortality after OS (7.5 +/- 1.3% to 7.4 +/- 1.1% to 8.3 +/- 3.7%, P < 0.001). Low-volume centers (< 15 repairs/year) did not present higher mortality rates. The number of EVARs per year in a center presented a positive association with EVAR mortality (Spearman correlation of 0.696, P = 0.004). Conclusions: The rate of repair of iAAA continues to grow, especially in patients aged >= 75 years and did not reach an inflection point yet. This is happening along with decreased repair mortality mainly because of the increased use of EVAR. Hospital mortality for iAAA repair is still a matter of concern, warranting further investigation and planning of vascular surgical services.

Copyright © 2020 Elsevier Inc. All rights reserved.

Keywords

• Aged; Aged, 80 and over; Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis Implantation; Clinical Protocols; Databases, Factual; Endovascular Procedures; Female; Hospital Mortality; Hospitals, High-Volume; Hospitals, Low-Volume; Humans; Male; Middle Aged; National Health Programs; Outcome and Process Assessment, Health Care; Portugal; Postoperative Complications; Registries; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; abdominal aortic aneurysm; aged; Article; endovascular aneurysm repair; female; hospital mortality; human; low volume hospital; major clinical study; male; mortality rate; open surgery; Portugal; priority journal; retrospective study; surgical mortality; very elderly; abdominal aortic aneurysm; adverse event; blood vessel transplantation; clinical protocol; comparative study; diagnostic imaging; endovascular surgery; factual database; high volume hospital; middle aged; mortality; postoperative complication; public health; register; risk assessmen