E-cadherin and CD44v6 in Gastric Cancer: Role, crosstalk and clinical implications
Dados básicos
- Código:
- Estudo Clínico Académico
- Protocolo:
- Estudo Clínico Académico
- EUDRACT:
- NCT:
- Centro:
- Dotação:
- Ano de início:
- 2021
- Ano de conclusão:
Objectivos do projeto
Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários
Documentos
- Não há documentos
Participantes
Stakeholders - Promotores
Outputs do ensaio clínico
CTNNA1 as a Hereditary Diffuse Gastric Cancer predisposing gene
Lobo, S, Oliveira, C
Meeting Abstract. 2022
BREAKING PERCEPTIONS: HOW TO EFFECTIVELY SUPPORT HEALTH PROFESSIONALS TO PARTICIPATE IN RESEARCH PROJECTS
Sousa, L, Carvalho, A, Oliveira, C
Meeting Abstract. 2022
CD44v6 high membranous expression as a predictive marker of therapy response in patients with gastric cancer
Park, Ji-Hyeon; (...); Oliveira, Carla
Meeting Abstract. 10.1200/JCO.2022.40.4_suppl.342. 2022
CD44v6 High Membranous Expression Is a Predictive Marker of Therapy Response in Gastric Cancer Patients
Almeida, GM; (...); Oliveira, C
Article. 10.3390/biomedicines9091249. 2021
Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer
Sao José, C; (...); Oliveira, C
Article. 10.1007/s10120-023-01395-0. 2023
Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness
Pereira, C; (...); Oliveira, C
Article. 10.1002/ijc.33872. 2022
Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness.
Pereira, C; (...); Oliveira, C
Article. 2022
Comprehensive copy number variant analysis of 11,000 previously unsolved rare disease exome sequencing datasets within the Solve-RD project results in diagnoses being reached for 2% of previously unsolved cases
Demidov, G; (...); Laurie, S
Meeting Abstract. 2023
CTNNA1 germline variants with a premature termination codon are a risk factor for development of early-onset Diffuse Gastric Cancer
Lobo, Silvana; (...); Oliveira, Carla
Meeting Abstract. 2024
CTNNA1 GERMLINE VARIANTS: DISEASE SPECTRUM EXTENDING BEYOND HEREDITARY DIFFUSE GASTRIC CANCER
Lobo, S; (...); Oliveira, C
Meeting Abstract. 2023
Disclosing CDH1 c.1901C>T as a founder pathogenic variant in the Portuguese population
Matos, R; (...); Oliveira, C
Meeting Abstract. 2023
Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGF beta 1 Promotes Tumour Growth.
Santos, M; (...); Oliveira, C
Article. 2022
Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFß1 Promotes Tumour Growth
Santos, M; (...); Oliveira, C
Article. 10.3390/biology11071046. 2022
Fibrosis-related transcriptome unveils a distinctive matrix remodelling pattern in penetrating but not in stricturing ileal Crohn's Disease
De Sousa, H. Tavares; (...); Magro, F.
Meeting Abstract. 2024
First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants
Coudert, M; (...); Colas, C
Article. 10.1136/jmg-2022-108740. 2022
First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants
Coudert, M; (...); Colas, C
Meeting Abstract. 2023
Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes
Garcia Pelaez, J; (...); Oliveira, C
Article. 10.1016/j.ejmg.2021.104401. 2022
Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes.
Garcia Pelaez, J; (...); Oliveira, C
Article. 2022
Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes
Garcia-Pelaez, J; (...); Oliveira, C
Article. 10.1016/S1470-2045(22)00643-X. 2023
Growth Factor-Free Vascularization of Marine-Origin Collagen Sponges Using Cryopreserved Stromal Vascular Fractions from Human Adipose Tissue.
Freitas-Ribeiro, S; (...); Pirraco, RP
Article. 2022
Head-up tilt test induced asystole and recurrent syncope: a follow-up study
Amador, A.; (...); Macedo, F.
Meeting Abstract. 2023
HER2 and PD-L1 Expression in Gastric and Gastroesophageal Junction Cancer: Insights for Combinatorial Targeting Approaches
Freitas, MB; (...); Duarte, HO
Article. 10.3390/cancers16061227. 2024
HuRthle cell tumors vs oncocytic variants of the follicular cell derived thyroid tumours: a comprehensive analysis based in transcriptome, proteome and cnv profiling
Canberk, S; (...); Maximo, VAB -
Article. 10.1530/endoabs.84.op-07-33. 2022
Optimising clinical care through CDH1-specific germline variant curation: improvement of clinical assertions and updated curation guidelines
Luo, Xi; (...); ClinGen CDH1 Variant Curation Expe
Article. 10.1136/jmg-2022-108807. 2023
Reducing Dietary Sodium and Improving Human Health 2.0
Moreira, P., Oliveira, C.
Article. 10.3390/nu15234965. 2023
Sixty years of the Bruce protocol: reappraising the contemporary role of exercise stress testing with electrocardiographic monitoring
Vilela, EM; (...); Fontes Carvalho, R.
Article. 10.1097/j.pbj.0000000000000235. 2023
The CDH1 c.1901C>T Variant: A Founder Variant in the Portuguese Population with Severe Impact in mRNA Splicing
Barbosa Matos, R; (...); Oliveira, C
Article. 10.3390/cancers13174464. 2021
THE CDH1 LOCUS REGULATORY ARCHITECTURE: CDH1 NONCODING ELEMENTS CONTROL E-CADHERIN CANONICAL FUNCTIONS
Jose, CS; (...); Oliveira, C
Meeting Abstract. 2022
THE FIRST CDH1 FOUNDER VARIANT IN THE PORTUGUESE POPULATION: A MISSENSE WITH SEVERE IMPACT IN MRNA SPLICING
Barbosa-Matos, R; (...); Oliveira, C
Meeting Abstract. 2022
The Identification of Large Rearrangements Involving Intron 2 of the CDH1 Gene in BRCA1/2 Negative and Breast Cancer Susceptibility
Ben Aissa-Haj, J; (...); Rouleau, E
Article. 10.3390/genes13122213. 2022
Unveiling the differential disease spectrum in carriers of Pathogenic and Likely Pathogenic germline CTNNA1 variants
Lobo, S; (...); Oliveira, C
Meeting Abstract. 2023
UPREGULATION OF TRNASER DRIVES GENOME ADAPTATION OF NSCLC TUMORS
Pinheiro, M; (...); Oliveira, C
Meeting Abstract. 2022
WHOLE GENOME SEQUENCING ANALYSIS: EXPLORING GERMLINE CNV LANDSCAPES
Ferreira, M; (...); Oliveira, C
Meeting Abstract. 2022