Portal de investigação
E-cadherin and CD44v6 in Gastric Cancer: Role, crosstalk and clinical implications
Dados básicos
- Código:
- Estudo Clínico Académico
- Protocolo:
- Estudo Clínico Académico
- EUDRACT:
- NCT:
- Centro:
- Dotação:
- Ano de início:
- 2021
- Ano de conclusão:
Objectivos do projeto
Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários
Documentos
- Não há documentos
Participantes
Stakeholders - Promotores
Outputs do ensaio clínico
CTNNA1 as a Hereditary Diffuse Gastric Cancer predisposing gene
Lobo, S, Oliveira, C
Meeting Abstract. 2022
BREAKING PERCEPTIONS: HOW TO EFFECTIVELY SUPPORT HEALTH PROFESSIONALS TO PARTICIPATE IN RESEARCH PROJECTS
Sousa, L, Carvalho, A, Oliveira, C
Meeting Abstract. 2022
CD44v6 high membranous expression as a predictive marker of therapy response in patients with gastric cancer
Meeting Abstract. 10.1200/JCO.2022.40.4_suppl.342. 2022
CD44v6 High Membranous Expression Is a Predictive Marker of Therapy Response in Gastric Cancer Patients
Almeida, GM; (...); Oliveira, C
Article. 10.3390/biomedicines9091249. 2021
Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer
Sao José, C; (...); Oliveira, C
Article. 10.1007/s10120-023-01395-0. 2023
Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness
Pereira, C; (...); Oliveira, C
Article. 10.1002/ijc.33872. 2022
Comprehensive copy number variant analysis of 11,000 previously unsolved rare disease exome sequencing datasets within the Solve-RD project results in diagnoses being reached for 2% of previously unsolved cases
Demidov, G; (...); Laurie, S
Meeting Abstract. 2023
CTNNA1 germline variants with a premature termination codon are a risk factor for development of early-onset Diffuse Gastric Cancer
Meeting Abstract. 2024
CTNNA1 GERMLINE VARIANTS: DISEASE SPECTRUM EXTENDING BEYOND HEREDITARY DIFFUSE GASTRIC CANCER
Lobo, S; (...); Oliveira, C
Meeting Abstract. 2023
Disclosing CDH1 c.1901C>T as a founder pathogenic variant in the Portuguese population
Matos, R; (...); Oliveira, C
Meeting Abstract. 2023
Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGF beta 1 Promotes Tumour Growth.
Article. 2022
Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFß1 Promotes Tumour Growth
Santos, M; (...); Oliveira, C
Article. 10.3390/biology11071046. 2022
Fibrosis-related transcriptome unveils a distinctive matrix remodelling pattern in penetrating but not in stricturing ileal Crohn's Disease
Meeting Abstract. 2024
First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants
Coudert, M; (...); Colas, C
Article. 10.1136/jmg-2022-108740. 2022
First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants
Coudert, M; (...); Colas, C
Meeting Abstract. 2023
Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes
Garcia Pelaez, J; (...); Oliveira, C
Article. 10.1016/j.ejmg.2021.104401. 2022
Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes.
Article. 2022
Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes
Garcia-Pelaez, J; (...); Oliveira, C
Article. 10.1016/S1470-2045(22)00643-X. 2023
HER2 and PD-L1 Expression in Gastric and Gastroesophageal Junction Cancer: Insights for Combinatorial Targeting Approaches
Article. 10.3390/cancers16061227. 2024
HuRthle cell tumors vs oncocytic variants of the follicular cell derived thyroid tumours: a comprehensive analysis based in transcriptome, proteome and cnv profiling
Article. 10.1530/endoabs.84.op-07-33. 2022
Optimising clinical care through CDH1-specific germline variant curation: improvement of clinical assertions and updated curation guidelines
Article. 10.1136/jmg-2022-108807. 2023
Reducing Dietary Sodium and Improving Human Health 2.0
Moreira, P., Oliveira, C.
Article. 10.3390/nu15234965. 2023
Sixty years of the Bruce protocol: reappraising the contemporary role of exercise stress testing with electrocardiographic monitoring
Vilela, EM; (...); Fontes Carvalho, R.
Article. 10.1097/j.pbj.0000000000000235. 2023
The CDH1 c.1901C>T Variant: A Founder Variant in the Portuguese Population with Severe Impact in mRNA Splicing
Barbosa Matos, R; (...); Oliveira, C
Article. 10.3390/cancers13174464. 2021
THE CDH1 LOCUS REGULATORY ARCHITECTURE: CDH1 NONCODING ELEMENTS CONTROL E-CADHERIN CANONICAL FUNCTIONS
Jose, CS; (...); Oliveira, C
Meeting Abstract. 2022
THE FIRST CDH1 FOUNDER VARIANT IN THE PORTUGUESE POPULATION: A MISSENSE WITH SEVERE IMPACT IN MRNA SPLICING
Barbosa-Matos, R; (...); Oliveira, C
Meeting Abstract. 2022
The Identification of Large Rearrangements Involving Intron 2 of the CDH1 Gene in BRCA1/2 Negative and Breast Cancer Susceptibility
Ben Aissa-Haj, J; (...); Rouleau, E
Article. 10.3390/genes13122213. 2022
Unveiling the differential disease spectrum in carriers of Pathogenic and Likely Pathogenic germline CTNNA1 variants
Lobo, S; (...); Oliveira, C
Meeting Abstract. 2023
UPREGULATION OF TRNASER DRIVES GENOME ADAPTATION OF NSCLC TUMORS
Pinheiro, M; (...); Oliveira, C
Meeting Abstract. 2022
WHOLE GENOME SEQUENCING ANALYSIS: EXPLORING GERMLINE CNV LANDSCAPES
Ferreira, M; (...); Oliveira, C
Meeting Abstract. 2022
