E-cadherin and CD44v6 in Gastric Cancer: Role, crosstalk and clinical implications

Dados básicos

Código:
Estudo Clínico Académico
Protocolo:
Estudo Clínico Académico
EUDRACT:
NCT:
Centro:
Dotação:
Ano de início:
2021
Ano de conclusão:
Estudos observacionais Nacional Não Financiado Outros

Objectivos do projeto

Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários

Documentos

  • Não há documentos

Participantes

Stakeholders - Promotores

FMUP

Outputs do ensaio clínico


CTNNA1 as a Hereditary Diffuse Gastric Cancer predisposing gene

Lobo, S, Oliveira, C

Meeting Abstract. 2022


BREAKING PERCEPTIONS: HOW TO EFFECTIVELY SUPPORT HEALTH PROFESSIONALS TO PARTICIPATE IN RESEARCH PROJECTS

Sousa, L, Carvalho, A, Oliveira, C

Meeting Abstract. 2022


CD44v6 high membranous expression as a predictive marker of therapy response in patients with gastric cancer

Park, Ji-Hyeon; (...); Oliveira, Carla

Meeting Abstract. 10.1200/JCO.2022.40.4_suppl.342. 2022


CD44v6 High Membranous Expression Is a Predictive Marker of Therapy Response in Gastric Cancer Patients

Almeida, GM; (...); Oliveira, C

Article. 10.3390/biomedicines9091249. 2021

  • Open Access.

Combined loss of CDH1 and downstream regulatory sequences drive early-onset diffuse gastric cancer and increase penetrance of hereditary diffuse gastric cancer

Sao José, C; (...); Oliveira, C

Article. 10.1007/s10120-023-01395-0. 2023

  • Open Access.

Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness

Pereira, C; (...); Oliveira, C

Article. 10.1002/ijc.33872. 2022

  • Open Access.

Comparison of East-Asia and West-Europe cohorts explains disparities in survival outcomes and highlights predictive biomarkers of early gastric cancer aggressiveness.

Pereira, C; (...); Oliveira, C

Article. 2022


Comprehensive copy number variant analysis of 11,000 previously unsolved rare disease exome sequencing datasets within the Solve-RD project results in diagnoses being reached for 2% of previously unsolved cases

Demidov, G; (...); Laurie, S

Meeting Abstract. 2023


CTNNA1 germline variants with a premature termination codon are a risk factor for development of early-onset Diffuse Gastric Cancer

Lobo, Silvana; (...); Oliveira, Carla

Meeting Abstract. 2024


CTNNA1 GERMLINE VARIANTS: DISEASE SPECTRUM EXTENDING BEYOND HEREDITARY DIFFUSE GASTRIC CANCER

Lobo, S; (...); Oliveira, C

Meeting Abstract. 2023


Disclosing CDH1 c.1901C>T as a founder pathogenic variant in the Portuguese population

Matos, R; (...); Oliveira, C

Meeting Abstract. 2023


Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGF beta 1 Promotes Tumour Growth.

Santos, M; (...); Oliveira, C

Article. 2022


Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFß1 Promotes Tumour Growth

Santos, M; (...); Oliveira, C

Article. 10.3390/biology11071046. 2022

  • Open Access.

Fibrosis-related transcriptome unveils a distinctive matrix remodelling pattern in penetrating but not in stricturing ileal Crohn's Disease

De Sousa, H. Tavares; (...); Magro, F.

Meeting Abstract. 2024


First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants

Coudert, M; (...); Colas, C

Article. 10.1136/jmg-2022-108740. 2022


First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants

Coudert, M; (...); Colas, C

Meeting Abstract. 2023


Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes

Garcia Pelaez, J; (...); Oliveira, C

Article. 10.1016/j.ejmg.2021.104401. 2022


Gastric cancer genetic predisposition and clinical presentations: Established heritable causes and potential candidate genes.

Garcia Pelaez, J; (...); Oliveira, C

Article. 2022


Genotype-first approach to identify associations between CDH1 germline variants and cancer phenotypes: a multicentre study by the European Reference Network on Genetic Tumour Risk Syndromes

Garcia-Pelaez, J; (...); Oliveira, C

Article. 10.1016/S1470-2045(22)00643-X. 2023

  • Open Access.

Growth Factor-Free Vascularization of Marine-Origin Collagen Sponges Using Cryopreserved Stromal Vascular Fractions from Human Adipose Tissue.

Freitas-Ribeiro, S; (...); Pirraco, RP

Article. 2022


Head-up tilt test induced asystole and recurrent syncope: a follow-up study

Amador, A.; (...); Macedo, F.

Meeting Abstract. 2023


HER2 and PD-L1 Expression in Gastric and Gastroesophageal Junction Cancer: Insights for Combinatorial Targeting Approaches

Freitas, MB; (...); Duarte, HO

Article. 10.3390/cancers16061227. 2024

  • Open Access.

HuRthle cell tumors vs oncocytic variants of the follicular cell derived thyroid tumours: a comprehensive analysis based in transcriptome, proteome and cnv profiling

Canberk, S; (...); Maximo, VAB -

Article. 10.1530/endoabs.84.op-07-33. 2022


Optimising clinical care through CDH1-specific germline variant curation: improvement of clinical assertions and updated curation guidelines

Luo, Xi; (...); ClinGen CDH1 Variant Curation Expe

Article. 10.1136/jmg-2022-108807. 2023

  • Open Access.

Reducing Dietary Sodium and Improving Human Health 2.0

Moreira, P., Oliveira, C.

Article. 10.3390/nu15234965. 2023


Sixty years of the Bruce protocol: reappraising the contemporary role of exercise stress testing with electrocardiographic monitoring

Vilela, EM; (...); Fontes Carvalho, R.

Article. 10.1097/j.pbj.0000000000000235. 2023


The CDH1 c.1901C>T Variant: A Founder Variant in the Portuguese Population with Severe Impact in mRNA Splicing

Barbosa Matos, R; (...); Oliveira, C

Article. 10.3390/cancers13174464. 2021

  • Open Access.

THE CDH1 LOCUS REGULATORY ARCHITECTURE: CDH1 NONCODING ELEMENTS CONTROL E-CADHERIN CANONICAL FUNCTIONS

Jose, CS; (...); Oliveira, C

Meeting Abstract. 2022


THE FIRST CDH1 FOUNDER VARIANT IN THE PORTUGUESE POPULATION: A MISSENSE WITH SEVERE IMPACT IN MRNA SPLICING

Barbosa-Matos, R; (...); Oliveira, C

Meeting Abstract. 2022


The Identification of Large Rearrangements Involving Intron 2 of the CDH1 Gene in BRCA1/2 Negative and Breast Cancer Susceptibility

Ben Aissa-Haj, J; (...); Rouleau, E

Article. 10.3390/genes13122213. 2022

  • Open Access.

Unveiling the differential disease spectrum in carriers of Pathogenic and Likely Pathogenic germline CTNNA1 variants

Lobo, S; (...); Oliveira, C

Meeting Abstract. 2023


UPREGULATION OF TRNASER DRIVES GENOME ADAPTATION OF NSCLC TUMORS

Pinheiro, M; (...); Oliveira, C

Meeting Abstract. 2022


WHOLE GENOME SEQUENCING ANALYSIS: EXPLORING GERMLINE CNV LANDSCAPES

Ferreira, M; (...); Oliveira, C

Meeting Abstract. 2022


Partilhar