Portal de investigação
Cardiac remodelling - Part 2: Clinical, imaging and laboratory findings. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology
Data de publicação:
Data Ahead of Print:
Autores da FMUP
Participantes de fora da FMUP
- Aimo, A
- Vergaro, G
- González, A
- Barison, A
- Lupón, J
- Delgado, V
- Richards, AM
- de Boer, RA
- Thum, T
- Arfsten, H
- Hulsmann, M
- Díez, J
- Foo, RSY
- Chan, MYY
- Anene-Nzelu, CG
- Abdelhamid, M
- Adamopoulos, S
- Anker, SD
- Belenkov, Y
- Gal, TB
- Cohen-Solal, A
- Böhm, M
- Chioncel, O
- Jankowska, EA
- Gustafsson, F
- Hill, L
- Jaarsma, T
- Januzzi, JL
- Jhund, P
- Lopatin, Y
- Lund, LH
- Metra, M
- Milicic, D
- Mueller, C
- Mullens, W
- Núñez, J
- Piepoli, MF
- Rakisheva, A
- Ristic, AD
- Rossignol, P
- Savarese, G
- Tocchetti, CG
- van Linthout, S
- Volterrani, M
- Seferovic, P
- Rosano, G
- Coats, AJS
- Emdin, M
- Bayes-Genis, A
Unidades de investigação
Abstract
In patients with heart failure, the beneficial effects of drug and device therapies counteract to some extent ongoing cardiac damage. According to the net balance between these two factors, cardiac geometry and function may improve (reverse remodelling, RR) and even completely normalize (remission), or vice versa progressively deteriorate (adverse remodelling, AR). RR or remission predict a better prognosis, while AR has been associated with worsening clinical status and outcomes. The remodelling process ultimately involves all cardiac chambers, but has been traditionally evaluated in terms of left ventricular volumes and ejection fraction. This is the second part of a review paper by the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology dedicated to ventricular remodelling. This document examines the proposed criteria to diagnose RR and AR, their prevalence and prognostic value, and the variables predicting remodelling in patients managed according to current guidelines. Much attention will be devoted to RR in patients with heart failure with reduced ejection fraction because most studies on cardiac remodelling focused on this setting.
Dados da publicação
- ISSN/ISSNe:
- 1388-9842, 1879-0844
- Tipo:
- Review
- Páginas:
- 944-958
- DOI:
- 10.1002/ejhf.2522
- Link para outro recurso:
- www.scopus.com
European Journal of Heart Failure Wiley-Blackwell
Citações Recebidas na Web of Science: 11
Citações Recebidas na Scopus: 25
Documentos
- Não há documentos
Filiações
Keywords
- Heart failure; Ejection fraction; Remodelling; Predictors; Imaging; Biomarkers; Therapies
Proyectos asociados
Cardiac Remodelling and “Recovery” in Pregnancy as a Model to Understand the Mechanisms of CV Diseases.
Investigador Principal: Inês Maria Falcão Sousa Pires Marques
Estudo Observacional Académico (PERIMYR) . SP Cardiologia . 2019
Remodelling adversely impacts arrhythmic outcome following isolated aortic valve replacement surgery
Investigador Principal: Inês Maria Falcão Sousa Pires Marques
Estudo Clínico Académico (Remodelling) . 2020
The Heart under Pressure: Mechanisms underlying HEpEF Secondary to chronic pressure Overload or Metabolic Syndrome
Investigador Principal: Inês Maria Falcão Sousa Pires Marques
Estudo Clínico Académico . 2020
Citar a publicação
Aimo A,Vergaro G,González A,Barison A,Lupón J,Delgado V,Richards AM,de Boer RA,Thum T,Arfsten H,Hulsmann M,Falcao I,Díez J,Foo RSY,Chan MYY,Anene CG,Abdelhamid M,Adamopoulos S,Anker SD,Belenkov Y,Gal TB,Cohen A,Böhm M,Chioncel O,Jankowska EA,Gustafsson F,Hill L,Jaarsma T,Januzzi JL,Jhund P,Lopatin Y,Lund LH,Metra M,Milicic D,Moura B,Mueller C,Mullens W,Núñez J,Piepoli MF,Rakisheva A,Ristic AD,Rossignol P,Savarese G,Tocchetti CG,van S,Volterrani M,Seferovic P,Rosano G,Coats A,Emdin M,Bayes A. Cardiac remodelling - Part 2: Clinical, imaging and laboratory findings. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology. Eur. J. Heart Fail. 2022. 24(6):p. 944-958. IF:18,200. (1).
