Non-Coding RNAs as Blood-Based Biomarkers in Cardiovascular Disease

Autores da FMUP

• Inês Maria Falcão Sousa Pires Marques

  Autor

Participantes de fora da FMUP

• Videira, RF
• Martins, PAD

Unidades de investigação

• Cirurgia e Fisiologia

• RISE-Health

  

  Investigador

  Fernando Carlos De Landér Schmitt

Abstract

In 2020, cardiovascular diseases (CVDs) remain a leading cause of mortality and morbidity, contributing to the burden of the already overloaded health system. Late or incorrect diagnosis of patients with CVDs compromises treatment efficiency and patient's outcome. Diagnosis of CVDs could be facilitated by detection of blood-based biomarkers that reliably reflect the current condition of the heart. In the last decade, non-coding RNAs (ncRNAs) present on human biofluids including serum, plasma, and blood have been reported as potential biomarkers for CVDs. This paper reviews recent studies that focus on the use of ncRNAs as biomarkers of CVDs.

Keywords

• ncRNAs; biomarkers; cardiovascular diseases; diagnosis