Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion: The Case of Breast Cancer

Data de publicação:

Autores da FMUP

  • Raquel Ângela Silva Soares Lino

    Autor

Participantes de fora da FMUP

  • Luis, C
  • Fernandes, R
  • Botelho, M

Unidades de investigação

Abstract

Cancer is a major health problem worldwide and the second leading cause of death following cardiovascular diseases. Breast cancer is the leading cause of mortality and morbidity among women and one of the most common malignant neoplasms prompt to metastatic disease. In the present review, the mechanisms of the major cell adhesion molecules involved in tumor invasion are discussed, focusing on the case of breast cancer. A non-systematic updated revision of the literature was performed in order to assemble information regarding the expression of the adhesion cell molecules associated with metastasis.

Dados da publicação

ISSN/ISSNe:
1566-5240, 1875-5666

Current Molecular Medicine  Bentham Science Publishers B.V.

Tipo:
Review
Páginas:
147-160
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 2

Citações Recebidas na Scopus: 4

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Keywords

  • Breast cancer; metastasis; cell adhesion molecules; cadherins; selectins; integrins; igcam

Proyectos asociados

Effects of Xanthohumol on Metabolic Syndrome Progression (XAN4Health) - NCT03561116

Investigador Principal: Raquel Ângela Silva Soares Lino

Ensaio Clínico Académico (XAN4Health) . TA XAN . 2019

SARS-CoV-2 e Angiogénese: uma ligação por explicar

Investigador Principal: Raquel Ângela Silva Soares Lino

Estudo Clínico Académico . 2021

The use of targeted angiogenic therapies for ischemic diabetic foot ulcer repair.

Investigador Principal: Raquel Ângela Silva Soares Lino

Estudo Clínico Académico . 2022

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