Portal de investigação
Effects of Xanthohumol on Metabolic Syndrome Progression (XAN4Health) - NCT03561116
Dados básicos
- Código:
- Ensaio Clínico Académico (XAN4Health)
- Protocolo:
- Ensaio Clínico Académico (XAN4Health)
- EUDRACT:
- NCT:
- NCT03561116
- Centro:
- Dotação:
- Ano de início:
- 2019
- Ano de conclusão:
Objectivos do projeto
Ensaio Clínico – Iniciativa da Academia; Fase: N/A; Subtipo: Tratamento; Natureza do Promotor: Academia – Tipo não comercial; Tipo de Centro: Multicêntrico – Centro de Ensaio: FMUP; Doença investigada: Síndrome metabólico – Participantes recrutados: 76
Documentos
- Não há documentos
Participantes
Unidades de investigação
Stakeholders - Promotores
Outputs do ensaio clínico
Faecalibacterium prausnitzii in Differentiated Thyroid Cancer Patients Treated with Radioiodine
Fernandes, A; (...); Barata, P
Article. 10.3390/nu15122680. 2023
In Situ Forming Silk Sericin-Based Hydrogel: A Novel Wound Healing Biomaterial
Baptista-Silva, S; (...); Oliveira, AL
Article. 10.1021/acsbiomaterials.0c01745. 2021
In vivo systemic toxicity assessment of an oxidized dextrin-based hydrogel and its effectiveness as a carrier and stabilizer of granular synthetic bone substitutes
Pereira, I; (...); Gama, FM
Article. 10.1002/jbm.a.36683. 2019
A retrospective study in tumour characteristics and clinical outcomes of overweight and obese women with breast cancer
Luis, C; (...); Soares, R.
Article. 10.1007/s10549-022-06836-5. 2022
A state of the art review on the novel mediator asprosin in the metabolic syndrome
Lu?s, C; (...); von Hafe, P
Article. 10.1097/j.pbj.0000000000000108. 2020
Ageing, cellular senescence and the impact of diet: an overview
Maduro, AT, Lu?s, C, Soares, R.
Article. 10.1097/j.pbj.0000000000000120. 2021
Alkaline phosphatase dual-binding sites for collagen dictate cell migration and microvessel assembly in vitro
Guerreiro, SG; (...); Kirkpatrick, CJ
Article. 10.1002/jcb.29835. 2021
Alkaline phosphatase dual-binding sites for collagen dictate cell migration and microvessel assembly in vitro.
Article. 2021
Antiangiogenic and Antioxidant In Vitro Properties of Hydroethanolic Extract from acai (Euterpe oleracea) Dietary Powder Supplement
Costa, R; (...); Carvalho, D.
Article. 10.3390/molecules26072011. 2021
Avoiding the Interference of Doxorubicin with MTT Measurements on the MCF-7 Breast Cancer Cell Line
Luis, C; (...); Fernandes, R
Article. 10.3390/mps2020029. 2019
Biocompatibility of the Biopolymer Cyanoflan for Applications in Skin Wound Healing
Costa, R; (...); Mota, R
Article. 10.3390/md19030147. 2021
Breast Cancer Molecular Subtypes Differentially Express Gluconeogenic Rate-Limiting Enzymes-Obesity as a Crucial Player.
Luís C; (...); Soares R
Article. 10.3390/cancers15204936. 2023
Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion: The Case of Breast Cancer
Luis, C; (...); Botelho, M
Review. 10.2174/1566524021666210806155231. 2023
Could Coprococcus catus be used as a biomarker for the treatment response of I-131 in thyroid cancer patients?
Fernandes, A, soares, r, Coelho, PB
Meeting Abstract. 2023
Diabetes: a silent player in musculoskeletal interventional radiology response
Dimitri Pinheiro, S; (...); Karantanas, A
Article. 10.1097/j.pbj.0000000000000112. 2021
Does body mass index influence surgical options and overall survival in breast cancer patients?
Luis, C; (...); Soares, R.
Article. 10.1007/s12094-023-03154-0. 2023
Early unhealthy eating habits underlie morpho-functional changes in the liver and adipose tissue in male rats.
Article. 2022
Effect of Radium-223 on the Gut Microbiota of Prostate Cancer Patients: A Pilot Case Series Study
Fernandes, A; (...); Barata, P
Article. 10.3390/cimb44100336. 2022
Effect of Raw and Roasted Phoenix dactylifera L. Seed Polyphenols Extracts on Suppression of Angiogenesis in Endothelial Cells
Moeenfard, M; (...); Costa, R
Article. 10.1007/s11130-022-01003-z. 2022
Epidemiological and Clinical Aspects of Cutaneous and Mucosal Leishmaniases in Portugal: Retrospective Analysis of Cases Diagnosed in Public Hospitals and Reported in the Literature between 2010 and 2020
Article. 10.3390/microorganisms12040819. 2024
Evaluation of the Antitumour and Antiproliferative Effect of Xanthohumol-Loaded PLGA Nanoparticles on Melanoma
Fonseca, M; (...); Fonte, P
Article. 10.3390/ma14216421. 2021
Exploring Silk Sericin for Diabetic Wounds: An In Situ-Forming Hydrogel to Protect against Oxidative Stress and Improve Tissue Healing and Regeneration
Baptista-Silva, S; (...); Oliveira, AL
Article. 10.3390/biom12060801. 2022
Exploring the Anti-Cancer Properties of Pomegranate Peel Aqueous Extract
Luís, C; (...); Duarte, MF
Article. 10.3390/app132111773. 2023
GLP-1R and IL-6 expression in the gastrointestinal tract of a murine model of metabolic syndrome
Costa, J; (...); Luis, C
Article. 10.46389/rjd-2022-1068. 2022
Grain Refinement of Inconel 718 Superalloy-The Effect of Rotating Magnetic Field
Silva, RP; (...); Silva, J
Article. 10.3390/ma15062038. 2022
High-fat diet promotes adrenaline production by visceral adipocytes
Gomes, A; (...); Ribeiro, L.
Article. 10.1007/s00394-019-01971-0. 2020
Human umbilical cord mesenchymal stem cells in type 2 diabetes mellitus: the emerging therapeutic approach
Gomes, A; (...); Costa, R
Article. 10.1007/s00441-021-03461-4. 2021
Impact of umbilical cord mesenchymal stromal/stem cell secretome and cord blood serum in prostate cancer progression
Sousa, A; (...); Gomes, A
Article. 10.1007/s13577-023-00880-z. 2023
Increased Galactosidase Beta 1 Expression as a Senescent Key Factor in ß-Cells Function Modulation at the Early Steps of Type 2 Diabetes
Maduro, AT; (...); Luis, C
Article. 10.1055/a-2044-8873. 2023
Influence of gut microbiota dysbiosis on brain function: a systematic review
Almeida, C; (...); Barata, P
Article. 10.1097/j.pbj.0000000000000059. 2020
Ionizing Radiation from Radiopharmaceuticals and the Human Gut Microbiota: An Ex Vivo Approach
Fernandes, A; (...); Barata, P
Article. 10.3390/ijms231810809. 2022
Long-Term Outcomes of Ultrasound-Guided Hydrodistension for Adhesive Capsulitis: A Prospective Observational Study
Dimitri-Pinheiro, S; (...); Karantanas, AH
Article. 10.3390/tomography9050147. 2023
Lower melanoma pulmonary metastatic burden in obese mice: role of FGF-21
Fonseca, M, Soares, R., Coelho, P
Article. 10.1097/cmr.0000000000000781. 2021
Metabolic Dysfunction Biomarkers as Predictors of Early Diabetes
Luís, C; (...); Fernandes, R
Review. 10.3390/biom11111589. 2021
Metabolic syndrome: what we know and what we need to know
Soares, R.
Article. 10.1097/j.pbj.0000000000000103. 2020
Metformin Reduces Vascular Assembly in High Glucose-Treated Human Microvascular Endothelial Cells in An AMPK-Independent Manner
Silva, C; (...); Soares, R.
Article. 10.22074/cellj.2021.7212. 2021
Mice with Type 2 Diabetes Present Significant Alterations in Their Tissue Biomechanical Properties and Histological Features
Cruz, TB; (...); Oliveira, M.
Article. 10.3390/biomedicines10010057. 2022
Nutritional senolytics and senomorphics: Implications to immune cells metabolism and aging - from theory to practice
Luis, C; (...); Ramalho, R
Article. 10.3389/fnut.2022.958563. 2022
Oxidative Stress Modulation and Radiosensitizing Effect of Quinoxaline-1,4-Dioxides Derivatives
Silva, L; (...); Vieira, M
Article. 10.2174/1871520619666191028091547. 2020
Regeneration in the Podarcis bocagei model organism: a comprehensive immune-/histochemical analysis of the tail
Luís, C; (...); Soares, R.
Article. 10.1007/s00435-019-00452-6. 2019
Serum inflammatory biomarkers are associated with increased choroidal thickness in keratoconus
Pinheiro Costa, J; (...); Carneiro, ?.
Article. 10.1038/s41598-023-37472-8. 2023
Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action
Weinhaupl, K; (...); Fraga, H
Article. 10.1016/j.jbc.2022.102553. 2022
Tackling endothelium remodeling in cardiovascular disease
Gul'asová, Z; (...); Tomecková, V
Article. 10.1002/jcb.29379. 2020
The Effects of Ionizing Radiation on Gut Microbiota, a Systematic Review
Fernandes, A; (...); Barata, P
Review. 10.3390/nu13093025. 2021
The Effects of Ionizing Radiation on Gut Microbiota: What Can Animal Models Tell Us?-A Systematic Review
Fernandes, A; (...); Barata, P
Review. 10.3390/cimb45050249. 2023
The Impact of Bariatric Surgery on Bone Health: State of the Art and New Recognized Links
Mendonça, F; (...); Freitas, P
Review. 10.1055/a-1767-5581. 2022
The Impact of Bariatric Surgery on Bone Health: State of the Art and New Recognized Links.
Review. 2022
The Impact of Flavonoid-Loaded Nanoparticles in the UV Protection and Safety Profile of Topical Sunscreens
Fonseca, M; (...); Fonte, P
Review. 10.3390/biom13030493. 2023
The Impact of Metabolic Syndrome and Type 2 Diabetes Mellitus on Prostate Cancer
Sousa, AP; (...); Fernandes, R
Article. 10.3389/fcell.2022.843458. 2022
The impact of obesity on bone health: an overview
Mendonca, FM; (...); Freitas, P
Article. 10.5603/ep.a2022.0063. 2022
The Influence of Adipocyte Secretome on Selected Metabolic Fingerprints of Breast Cancer Cell Lines Representing the Four Major Breast Cancer Subtypes
Luis, C; (...); Soares, R.
Article. 10.3390/cells12172123. 2023
The Microbiome of the Nose-Friend or Foe?
Dimitri Pinheiro, S, Soares, R., Barata, P
Review. 10.1177/2152656720911605. 2020
The misunderstood link between SARS-CoV-2 and angiogenesis. A narrative review
Madureira, G, Soares, R.
Article. 10.1016/j.pulmoe.2021.08.004. 2021
Type 2 Diabetes mellitus alters the cargo of (poly)phenol metabolome and the oxidative status in circulating lipoproteins
Reis, A; (...); Freitas, V.
Article. 10.1016/j.redox.2022.102572. 2023
Ultrasound-guided hydrodistension for adhesive capsulitis: a longitudinal study on the effect of diabetes on treatment outcomes
Dimitri-Pinheiro, S; (...); Karantanas, AH
Article. 10.1007/s00256-022-04141-2. 2022
Underestimated Prediabetic Biomarkers: Are We Blind to Their Strategy?
Lu?s, C; (...); Fernandes, R
Article. 10.3389/fendo.2022.805837. 2022
Unhealthy Diets Induce Distinct and Regional Effects on Intestinal Inflammatory Signalling Pathways and Long-Lasting Metabolic Dysfunction in Rats
Nogueira, S; (...); Leal, S
Article. 10.3390/ijms231810984. 2022
