Effects of Xanthohumol on Metabolic Syndrome Progression (XAN4Health) - NCT03561116

Dados básicos

Código:
Ensaio Clínico Académico (XAN4Health)
Protocolo:
Ensaio Clínico Académico (XAN4Health)
EUDRACT:
NCT:
NCT03561116
Centro:
Dotação:
Ano de início:
2019
Ano de conclusão:
Ensaios clínicos Nacional Outros Financiamentos Privada

Objectivos do projeto

Ensaio Clínico – Iniciativa da Academia; Fase: N/A; Subtipo: Tratamento; Natureza do Promotor: Academia – Tipo não comercial; Tipo de Centro: Multicêntrico – Centro de Ensaio: FMUP; Doença investigada: Síndrome metabólico – Participantes recrutados: 76

Documentos

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Participantes

Unidades de investigação

Stakeholders - Promotores

TA XAN
TA XAN

Outputs do ensaio clínico


Faecalibacterium prausnitzii in Differentiated Thyroid Cancer Patients Treated with Radioiodine

Fernandes, A; (...); Barata, P

Article. 10.3390/nu15122680. 2023

  • Open Access.

In Situ Forming Silk Sericin-Based Hydrogel: A Novel Wound Healing Biomaterial

Baptista-Silva, S; (...); Oliveira, AL

Article. 10.1021/acsbiomaterials.0c01745. 2021


In vivo systemic toxicity assessment of an oxidized dextrin-based hydrogel and its effectiveness as a carrier and stabilizer of granular synthetic bone substitutes

Pereira, I; (...); Gama, FM

Article. 10.1002/jbm.a.36683. 2019

  • Open Access.

A retrospective study in tumour characteristics and clinical outcomes of overweight and obese women with breast cancer

Luis, C; (...); Soares, R.

Article. 10.1007/s10549-022-06836-5. 2022

  • Open Access.

A state of the art review on the novel mediator asprosin in the metabolic syndrome

Lu?s, C; (...); von Hafe, P

Article. 10.1097/j.pbj.0000000000000108. 2020


Ageing, cellular senescence and the impact of diet: an overview

Maduro, AT, Lu?s, C, Soares, R.

Article. 10.1097/j.pbj.0000000000000120. 2021


Alkaline phosphatase dual-binding sites for collagen dictate cell migration and microvessel assembly in vitro

Guerreiro, SG; (...); Kirkpatrick, CJ

Article. 10.1002/jcb.29835. 2021


Alkaline phosphatase dual-binding sites for collagen dictate cell migration and microvessel assembly in vitro.

Guerreiro, SG; (...); Kirkpatrick, CJ

Article. 2021


Antiangiogenic and Antioxidant In Vitro Properties of Hydroethanolic Extract from acai (Euterpe oleracea) Dietary Powder Supplement

Costa, R; (...); Carvalho, D.

Article. 10.3390/molecules26072011. 2021

  • Open Access.

Avoiding the Interference of Doxorubicin with MTT Measurements on the MCF-7 Breast Cancer Cell Line

Luis, C; (...); Fernandes, R

Article. 10.3390/mps2020029. 2019

  • Open Access.

Biocompatibility of the Biopolymer Cyanoflan for Applications in Skin Wound Healing

Costa, R; (...); Mota, R

Article. 10.3390/md19030147. 2021

  • Open Access.

Bird Fancier's Lung Diagnosis in Times of COVID-19

Cardoso, Ana; (...); de Lacerda, Antonio Pais

Letter. 10.1016/j.arbres.2020.09.016. 2021

  • Open Access.

Breast Cancer Molecular Subtypes Differentially Express Gluconeogenic Rate-Limiting Enzymes-Obesity as a Crucial Player.

Luís C; (...); Soares R

Article. 10.3390/cancers15204936. 2023

  • Open Access.

Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion: The Case of Breast Cancer

Luis, C; (...); Botelho, M

Review. 10.2174/1566524021666210806155231. 2023


Could Coprococcus catus be used as a biomarker for the treatment response of I-131 in thyroid cancer patients?

Fernandes, A, soares, r, Coelho, PB

Meeting Abstract. 2023


Diabetes: a silent player in musculoskeletal interventional radiology response

Dimitri Pinheiro, S; (...); Karantanas, A

Article. 10.1097/j.pbj.0000000000000112. 2021


Does body mass index influence surgical options and overall survival in breast cancer patients?

Luis, C; (...); Soares, R.

Article. 10.1007/s12094-023-03154-0. 2023

  • Open Access.

Early unhealthy eating habits underlie morpho-functional changes in the liver and adipose tissue in male rats.

Nogueira, S; (...); Leal, S

Article. 2022


Effect of Radium-223 on the Gut Microbiota of Prostate Cancer Patients: A Pilot Case Series Study

Fernandes, A; (...); Barata, P

Article. 10.3390/cimb44100336. 2022

  • Open Access.

Effect of Raw and Roasted Phoenix dactylifera L. Seed Polyphenols Extracts on Suppression of Angiogenesis in Endothelial Cells

Moeenfard, M; (...); Costa, R

Article. 10.1007/s11130-022-01003-z. 2022


Epidemiological and Clinical Aspects of Cutaneous and Mucosal Leishmaniases in Portugal: Retrospective Analysis of Cases Diagnosed in Public Hospitals and Reported in the Literature between 2010 and 2020

Rocha, R; (...); Maia, C

Article. 10.3390/microorganisms12040819. 2024

  • Open Access.

Evaluation of the Antitumour and Antiproliferative Effect of Xanthohumol-Loaded PLGA Nanoparticles on Melanoma

Fonseca, M; (...); Fonte, P

Article. 10.3390/ma14216421. 2021

  • Open Access.

Exploring Silk Sericin for Diabetic Wounds: An In Situ-Forming Hydrogel to Protect against Oxidative Stress and Improve Tissue Healing and Regeneration

Baptista-Silva, S; (...); Oliveira, AL

Article. 10.3390/biom12060801. 2022

  • Open Access.

Exploring the Anti-Cancer Properties of Pomegranate Peel Aqueous Extract

Luís, C; (...); Duarte, MF

Article. 10.3390/app132111773. 2023

  • Open Access.

GLP-1R and IL-6 expression in the gastrointestinal tract of a murine model of metabolic syndrome

Costa, J; (...); Luis, C

Article. 10.46389/rjd-2022-1068. 2022


Grain Refinement of Inconel 718 Superalloy-The Effect of Rotating Magnetic Field

Silva, RP; (...); Silva, J

Article. 10.3390/ma15062038. 2022


High-fat diet promotes adrenaline production by visceral adipocytes

Gomes, A; (...); Ribeiro, L.

Article. 10.1007/s00394-019-01971-0. 2020


Human umbilical cord mesenchymal stem cells in type 2 diabetes mellitus: the emerging therapeutic approach

Gomes, A; (...); Costa, R

Article. 10.1007/s00441-021-03461-4. 2021


Impact of umbilical cord mesenchymal stromal/stem cell secretome and cord blood serum in prostate cancer progression

Sousa, A; (...); Gomes, A

Article. 10.1007/s13577-023-00880-z. 2023

  • Open Access.

Increased Galactosidase Beta 1 Expression as a Senescent Key Factor in ß-Cells Function Modulation at the Early Steps of Type 2 Diabetes

Maduro, AT; (...); Luis, C

Article. 10.1055/a-2044-8873. 2023


Influence of gut microbiota dysbiosis on brain function: a systematic review

Almeida, C; (...); Barata, P

Article. 10.1097/j.pbj.0000000000000059. 2020


Ionizing Radiation from Radiopharmaceuticals and the Human Gut Microbiota: An Ex Vivo Approach

Fernandes, A; (...); Barata, P

Article. 10.3390/ijms231810809. 2022

  • Open Access.

Long-Term Outcomes of Ultrasound-Guided Hydrodistension for Adhesive Capsulitis: A Prospective Observational Study

Dimitri-Pinheiro, S; (...); Karantanas, AH

Article. 10.3390/tomography9050147. 2023

  • Open Access.

Lower melanoma pulmonary metastatic burden in obese mice: role of FGF-21

Fonseca, M, Soares, R., Coelho, P

Article. 10.1097/cmr.0000000000000781. 2021


Metabolic Dysfunction Biomarkers as Predictors of Early Diabetes

Luís, C; (...); Fernandes, R

Review. 10.3390/biom11111589. 2021

  • Open Access.

Metabolic syndrome: what we know and what we need to know

Soares, R.

Article. 10.1097/j.pbj.0000000000000103. 2020


Metformin Reduces Vascular Assembly in High Glucose-Treated Human Microvascular Endothelial Cells in An AMPK-Independent Manner

Silva, C; (...); Soares, R.

Article. 10.22074/cellj.2021.7212. 2021


Mice with Type 2 Diabetes Present Significant Alterations in Their Tissue Biomechanical Properties and Histological Features

Cruz, TB; (...); Oliveira, M.

Article. 10.3390/biomedicines10010057. 2022

  • Open Access.

Nutritional senolytics and senomorphics: Implications to immune cells metabolism and aging - from theory to practice

Luis, C; (...); Ramalho, R

Article. 10.3389/fnut.2022.958563. 2022

  • Open Access.

Oxidative Stress Modulation and Radiosensitizing Effect of Quinoxaline-1,4-Dioxides Derivatives

Silva, L; (...); Vieira, M

Article. 10.2174/1871520619666191028091547. 2020


Ptosis, Areflexia and Ataxia in a 4-year-old Girl.

Ferreira, SH; (...); soares, r

Article. 2021


Regeneration in the Podarcis bocagei model organism: a comprehensive immune-/histochemical analysis of the tail

Luís, C; (...); Soares, R.

Article. 10.1007/s00435-019-00452-6. 2019


Serum inflammatory biomarkers are associated with increased choroidal thickness in keratoconus

Pinheiro Costa, J; (...); Carneiro, ?.

Article. 10.1038/s41598-023-37472-8. 2023

  • Open Access.

Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action

Weinhaupl, K; (...); Fraga, H

Article. 10.1016/j.jbc.2022.102553. 2022

  • Open Access.

Tackling endothelium remodeling in cardiovascular disease

Gul'asová, Z; (...); Tomecková, V

Article. 10.1002/jcb.29379. 2020


The Effects of Ionizing Radiation on Gut Microbiota, a Systematic Review

Fernandes, A; (...); Barata, P

Review. 10.3390/nu13093025. 2021

  • Open Access.

The Effects of Ionizing Radiation on Gut Microbiota: What Can Animal Models Tell Us?-A Systematic Review

Fernandes, A; (...); Barata, P

Review. 10.3390/cimb45050249. 2023

  • Open Access.

The Impact of Bariatric Surgery on Bone Health: State of the Art and New Recognized Links

Mendonça, F; (...); Freitas, P

Review. 10.1055/a-1767-5581. 2022

  • Open Access.

The Impact of Bariatric Surgery on Bone Health: State of the Art and New Recognized Links.

Mendonca, F; (...); Freitas, P

Review. 2022


The Impact of Flavonoid-Loaded Nanoparticles in the UV Protection and Safety Profile of Topical Sunscreens

Fonseca, M; (...); Fonte, P

Review. 10.3390/biom13030493. 2023

  • Open Access.

The Impact of Metabolic Syndrome and Type 2 Diabetes Mellitus on Prostate Cancer

Sousa, AP; (...); Fernandes, R

Article. 10.3389/fcell.2022.843458. 2022

  • Open Access.

The impact of obesity on bone health: an overview

Mendonca, FM; (...); Freitas, P

Article. 10.5603/ep.a2022.0063. 2022

  • Open Access.

The impact of obesity on bone health: an overview.

Mendonca, FM; (...); Freitas, P

Review. 2022


The Influence of Adipocyte Secretome on Selected Metabolic Fingerprints of Breast Cancer Cell Lines Representing the Four Major Breast Cancer Subtypes

Luis, C; (...); Soares, R.

Article. 10.3390/cells12172123. 2023

  • Open Access.

The Microbiome of the Nose-Friend or Foe?

Dimitri Pinheiro, S, Soares, R., Barata, P

Review. 10.1177/2152656720911605. 2020

  • Open Access.

The misunderstood link between SARS-CoV-2 and angiogenesis. A narrative review

Madureira, G, Soares, R.

Article. 10.1016/j.pulmoe.2021.08.004. 2021

  • Open Access.

Type 2 Diabetes mellitus alters the cargo of (poly)phenol metabolome and the oxidative status in circulating lipoproteins

Reis, A; (...); Freitas, V.

Article. 10.1016/j.redox.2022.102572. 2023

  • Open Access.

Ultrasound-guided hydrodistension for adhesive capsulitis: a longitudinal study on the effect of diabetes on treatment outcomes

Dimitri-Pinheiro, S; (...); Karantanas, AH

Article. 10.1007/s00256-022-04141-2. 2022


Underestimated Prediabetic Biomarkers: Are We Blind to Their Strategy?

Lu?s, C; (...); Fernandes, R

Article. 10.3389/fendo.2022.805837. 2022

  • Open Access.

Unhealthy Diets Induce Distinct and Regional Effects on Intestinal Inflammatory Signalling Pathways and Long-Lasting Metabolic Dysfunction in Rats

Nogueira, S; (...); Leal, S

Article. 10.3390/ijms231810984. 2022

  • Open Access.

A Systematic Scoping Review Of Vascular Cell Senescence In Atherosclerosis: An Innovative Perspective And Therapeutic Approach

Projeto de fim de curso

Colaboradores: Raquel Ângela Silva Soares Lino


Sars-Cov-2 E Angiogénese: Uma Ligação Por Explicar

Trabalho final de curso

Colaboradores: Raquel Ângela Silva Soares Lino


Sars-Cov-2 E Angiogénese: Uma Ligação Por Explicar

Dissertação de Mestrado

Colaboradores: Raquel Ângela Silva Soares Lino


Targeting The Endotedial Cell Metabolism And Function Crosstalk As A Means To Unravel The Angiogenic Paradox In Type 1 Diabetes Mellitus

Tese de doutoramento

Colaboradores: Raquel Ângela Silva Soares Lino


The Use Of Targeted Angiogenic Therapies For Ischemic Diabetic Foot Ulcer Repair.

Trabalho final de curso

Colaboradores: Raquel Ângela Silva Soares Lino


The Use Of Targeted Angiogenic Therapies For Ischemic Diabetic Foot Ulcer Repair.

Dissertação de Mestrado

Colaboradores: Raquel Ângela Silva Soares Lino


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