Effects of Xanthohumol on Metabolic Syndrome Progression (XAN4Health) - NCT03561116
Dados básicos
- Código:
- Ensaio Clínico Académico (XAN4Health)
- Protocolo:
- Ensaio Clínico Académico (XAN4Health)
- EUDRACT:
- NCT:
- NCT03561116
- Centro:
- Dotação:
- Ano de início:
- 2019
- Ano de conclusão:
Objectivos do projeto
Ensaio Clínico – Iniciativa da Academia; Fase: N/A; Subtipo: Tratamento; Natureza do Promotor: Academia – Tipo não comercial; Tipo de Centro: Multicêntrico – Centro de Ensaio: FMUP; Doença investigada: Síndrome metabólico – Participantes recrutados: 76
Documentos
- Não há documentos
Participantes
Unidades de investigação
Stakeholders - Promotores
Outputs do ensaio clínico
Faecalibacterium prausnitzii in Differentiated Thyroid Cancer Patients Treated with Radioiodine
Fernandes, A; (...); Barata, P
Article. 10.3390/nu15122680. 2023
In Situ Forming Silk Sericin-Based Hydrogel: A Novel Wound Healing Biomaterial
Baptista-Silva, S; (...); Oliveira, AL
Article. 10.1021/acsbiomaterials.0c01745. 2021
In vivo systemic toxicity assessment of an oxidized dextrin-based hydrogel and its effectiveness as a carrier and stabilizer of granular synthetic bone substitutes
Pereira, I; (...); Gama, FM
Article. 10.1002/jbm.a.36683. 2019
A retrospective study in tumour characteristics and clinical outcomes of overweight and obese women with breast cancer
Luis, C; (...); Soares, R.
Article. 10.1007/s10549-022-06836-5. 2022
A state of the art review on the novel mediator asprosin in the metabolic syndrome
Lu?s, C; (...); von Hafe, P
Article. 10.1097/j.pbj.0000000000000108. 2020
Ageing, cellular senescence and the impact of diet: an overview
Maduro, AT, Lu?s, C, Soares, R.
Article. 10.1097/j.pbj.0000000000000120. 2021
Alkaline phosphatase dual-binding sites for collagen dictate cell migration and microvessel assembly in vitro
Guerreiro, SG; (...); Kirkpatrick, CJ
Article. 10.1002/jcb.29835. 2021
Alkaline phosphatase dual-binding sites for collagen dictate cell migration and microvessel assembly in vitro.
Guerreiro, SG; (...); Kirkpatrick, CJ
Article. 2021
Antiangiogenic and Antioxidant In Vitro Properties of Hydroethanolic Extract from acai (Euterpe oleracea) Dietary Powder Supplement
Costa, R; (...); Carvalho, D.
Article. 10.3390/molecules26072011. 2021
Avoiding the Interference of Doxorubicin with MTT Measurements on the MCF-7 Breast Cancer Cell Line
Luis, C; (...); Fernandes, R
Article. 10.3390/mps2020029. 2019
Biocompatibility of the Biopolymer Cyanoflan for Applications in Skin Wound Healing
Costa, R; (...); Mota, R
Article. 10.3390/md19030147. 2021
Bird Fancier's Lung Diagnosis in Times of COVID-19
Cardoso, Ana; (...); de Lacerda, Antonio Pais
Letter. 10.1016/j.arbres.2020.09.016. 2021
Breast Cancer Molecular Subtypes Differentially Express Gluconeogenic Rate-Limiting Enzymes-Obesity as a Crucial Player.
Luís C; (...); Soares R
Article. 10.3390/cancers15204936. 2023
Cell-adhesion Molecules as Key Mechanisms of Tumor Invasion: The Case of Breast Cancer
Luis, C; (...); Botelho, M
Review. 10.2174/1566524021666210806155231. 2023
Could Coprococcus catus be used as a biomarker for the treatment response of I-131 in thyroid cancer patients?
Fernandes, A, soares, r, Coelho, PB
Meeting Abstract. 2023
Diabetes: a silent player in musculoskeletal interventional radiology response
Dimitri Pinheiro, S; (...); Karantanas, A
Article. 10.1097/j.pbj.0000000000000112. 2021
Does body mass index influence surgical options and overall survival in breast cancer patients?
Luis, C; (...); Soares, R.
Article. 10.1007/s12094-023-03154-0. 2023
Early unhealthy eating habits underlie morpho-functional changes in the liver and adipose tissue in male rats.
Nogueira, S; (...); Leal, S
Article. 2022
Effect of Radium-223 on the Gut Microbiota of Prostate Cancer Patients: A Pilot Case Series Study
Fernandes, A; (...); Barata, P
Article. 10.3390/cimb44100336. 2022
Effect of Raw and Roasted Phoenix dactylifera L. Seed Polyphenols Extracts on Suppression of Angiogenesis in Endothelial Cells
Moeenfard, M; (...); Costa, R
Article. 10.1007/s11130-022-01003-z. 2022
Epidemiological and Clinical Aspects of Cutaneous and Mucosal Leishmaniases in Portugal: Retrospective Analysis of Cases Diagnosed in Public Hospitals and Reported in the Literature between 2010 and 2020
Rocha, R; (...); Maia, C
Article. 10.3390/microorganisms12040819. 2024
Evaluation of the Antitumour and Antiproliferative Effect of Xanthohumol-Loaded PLGA Nanoparticles on Melanoma
Fonseca, M; (...); Fonte, P
Article. 10.3390/ma14216421. 2021
Exploring Silk Sericin for Diabetic Wounds: An In Situ-Forming Hydrogel to Protect against Oxidative Stress and Improve Tissue Healing and Regeneration
Baptista-Silva, S; (...); Oliveira, AL
Article. 10.3390/biom12060801. 2022
Exploring the Anti-Cancer Properties of Pomegranate Peel Aqueous Extract
Luís, C; (...); Duarte, MF
Article. 10.3390/app132111773. 2023
GLP-1R and IL-6 expression in the gastrointestinal tract of a murine model of metabolic syndrome
Costa, J; (...); Luis, C
Article. 10.46389/rjd-2022-1068. 2022
Grain Refinement of Inconel 718 Superalloy-The Effect of Rotating Magnetic Field
Silva, RP; (...); Silva, J
Article. 10.3390/ma15062038. 2022
High-fat diet promotes adrenaline production by visceral adipocytes
Gomes, A; (...); Ribeiro, L.
Article. 10.1007/s00394-019-01971-0. 2020
Human umbilical cord mesenchymal stem cells in type 2 diabetes mellitus: the emerging therapeutic approach
Gomes, A; (...); Costa, R
Article. 10.1007/s00441-021-03461-4. 2021
Impact of umbilical cord mesenchymal stromal/stem cell secretome and cord blood serum in prostate cancer progression
Sousa, A; (...); Gomes, A
Article. 10.1007/s13577-023-00880-z. 2023
Increased Galactosidase Beta 1 Expression as a Senescent Key Factor in ß-Cells Function Modulation at the Early Steps of Type 2 Diabetes
Maduro, AT; (...); Luis, C
Article. 10.1055/a-2044-8873. 2023
Influence of gut microbiota dysbiosis on brain function: a systematic review
Almeida, C; (...); Barata, P
Article. 10.1097/j.pbj.0000000000000059. 2020
Ionizing Radiation from Radiopharmaceuticals and the Human Gut Microbiota: An Ex Vivo Approach
Fernandes, A; (...); Barata, P
Article. 10.3390/ijms231810809. 2022
Long-Term Outcomes of Ultrasound-Guided Hydrodistension for Adhesive Capsulitis: A Prospective Observational Study
Dimitri-Pinheiro, S; (...); Karantanas, AH
Article. 10.3390/tomography9050147. 2023
Lower melanoma pulmonary metastatic burden in obese mice: role of FGF-21
Fonseca, M, Soares, R., Coelho, P
Article. 10.1097/cmr.0000000000000781. 2021
Metabolic Dysfunction Biomarkers as Predictors of Early Diabetes
Luís, C; (...); Fernandes, R
Review. 10.3390/biom11111589. 2021
Metabolic syndrome: what we know and what we need to know
Soares, R.
Article. 10.1097/j.pbj.0000000000000103. 2020
Metformin Reduces Vascular Assembly in High Glucose-Treated Human Microvascular Endothelial Cells in An AMPK-Independent Manner
Silva, C; (...); Soares, R.
Article. 10.22074/cellj.2021.7212. 2021
Mice with Type 2 Diabetes Present Significant Alterations in Their Tissue Biomechanical Properties and Histological Features
Cruz, TB; (...); Oliveira, M.
Article. 10.3390/biomedicines10010057. 2022
Nutritional senolytics and senomorphics: Implications to immune cells metabolism and aging - from theory to practice
Luis, C; (...); Ramalho, R
Article. 10.3389/fnut.2022.958563. 2022
Oxidative Stress Modulation and Radiosensitizing Effect of Quinoxaline-1,4-Dioxides Derivatives
Silva, L; (...); Vieira, M
Article. 10.2174/1871520619666191028091547. 2020
Regeneration in the Podarcis bocagei model organism: a comprehensive immune-/histochemical analysis of the tail
Luís, C; (...); Soares, R.
Article. 10.1007/s00435-019-00452-6. 2019
Serum inflammatory biomarkers are associated with increased choroidal thickness in keratoconus
Pinheiro Costa, J; (...); Carneiro, ?.
Article. 10.1038/s41598-023-37472-8. 2023
Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action
Weinhaupl, K; (...); Fraga, H
Article. 10.1016/j.jbc.2022.102553. 2022
Tackling endothelium remodeling in cardiovascular disease
Gul'asová, Z; (...); Tomecková, V
Article. 10.1002/jcb.29379. 2020
The Effects of Ionizing Radiation on Gut Microbiota, a Systematic Review
Fernandes, A; (...); Barata, P
Review. 10.3390/nu13093025. 2021
The Effects of Ionizing Radiation on Gut Microbiota: What Can Animal Models Tell Us?-A Systematic Review
Fernandes, A; (...); Barata, P
Review. 10.3390/cimb45050249. 2023
The Impact of Bariatric Surgery on Bone Health: State of the Art and New Recognized Links
Mendonça, F; (...); Freitas, P
Review. 10.1055/a-1767-5581. 2022
The Impact of Bariatric Surgery on Bone Health: State of the Art and New Recognized Links.
Mendonca, F; (...); Freitas, P
Review. 2022
The Impact of Flavonoid-Loaded Nanoparticles in the UV Protection and Safety Profile of Topical Sunscreens
Fonseca, M; (...); Fonte, P
Review. 10.3390/biom13030493. 2023
The Impact of Metabolic Syndrome and Type 2 Diabetes Mellitus on Prostate Cancer
Sousa, AP; (...); Fernandes, R
Article. 10.3389/fcell.2022.843458. 2022
The impact of obesity on bone health: an overview
Mendonca, FM; (...); Freitas, P
Article. 10.5603/ep.a2022.0063. 2022
The Influence of Adipocyte Secretome on Selected Metabolic Fingerprints of Breast Cancer Cell Lines Representing the Four Major Breast Cancer Subtypes
Luis, C; (...); Soares, R.
Article. 10.3390/cells12172123. 2023
The Microbiome of the Nose-Friend or Foe?
Dimitri Pinheiro, S, Soares, R., Barata, P
Review. 10.1177/2152656720911605. 2020
The misunderstood link between SARS-CoV-2 and angiogenesis. A narrative review
Madureira, G, Soares, R.
Article. 10.1016/j.pulmoe.2021.08.004. 2021
Type 2 Diabetes mellitus alters the cargo of (poly)phenol metabolome and the oxidative status in circulating lipoproteins
Reis, A; (...); Freitas, V.
Article. 10.1016/j.redox.2022.102572. 2023
Ultrasound-guided hydrodistension for adhesive capsulitis: a longitudinal study on the effect of diabetes on treatment outcomes
Dimitri-Pinheiro, S; (...); Karantanas, AH
Article. 10.1007/s00256-022-04141-2. 2022
Underestimated Prediabetic Biomarkers: Are We Blind to Their Strategy?
Lu?s, C; (...); Fernandes, R
Article. 10.3389/fendo.2022.805837. 2022
Unhealthy Diets Induce Distinct and Regional Effects on Intestinal Inflammatory Signalling Pathways and Long-Lasting Metabolic Dysfunction in Rats
Nogueira, S; (...); Leal, S
Article. 10.3390/ijms231810984. 2022