The impact of obesity on bone health: an overview

Autores da FMUP

• Raquel Ângela Silva Soares Lino

  Autor

• Davide Maurício Costa Carvalho

  Autor

• Paula Isabel Marques Simões De Freitas

  Autor

Participantes de fora da FMUP

• Mendonca, FM

Unidades de investigação

• Biomedicina

• Medicina

Abstract

Obesity is a major health problem that has multisystemic consequences. One of the addressed topics in the current investigation regards the influence of obesity on bone metabolism. Despite of the broadly accepted notion that obesity is associated with a positive effect on bone health, recent evidence has challenged this idea by suggesting an increased risk of fracture in specific sites. Therefore, this review intends to review succinctly the intricate connections between obesity and bone metabolism by addressing the roles of the mechanical, inflammatory, and hormonal factors, among others. It will also focus on the overall impact on bone mineral density and bone fracture occurrence.

Keywords

• obesity; bone metabolism; bone mineral density; fractures