Risk characterization of dietary acrylamide exposure and associated factors in the Portuguese population

Data de publicação: Data Ahead of Print:

Autores da FMUP

  • Daniela Macedo Correia

    Autor

  • Milton Severo Barros Da Silva

    Autor

  • Carla Maria De Moura Lopes

    Autor

Participantes de fora da FMUP

  • Costa, SA
  • Carvalho, C
  • Vilela, S.
  • Torres, D.

Unidades de investigação

Abstract

Acrylamide exposure, mainly resulting from food cooking and processing, has been associated with a higher risk of health problems, due to genotoxic effects. This study aims to estimate acrylamide dietary exposure of the Portuguese population and its associated factors. Dietary data collected through 2 non-consecutive 24 hour recalls or food diaries from a representative sample of the Portuguese population from the National Food, Nutrition and Physical Activity Survey was used (n = 5811; 3-84 years). Occurrence data of acrylamide in food were obtained from EFSA. The margins of exposure (MOE) were calculated for peripheral neuropathy and neoplastic effects. The association between acrylamide and socio-demographic characteristics was estimated through linear regression models. For the total population, the estimated median daily dietary exposure per body weight to acrylamide was 0.38 mu g/kg/day, ranging from 0.14 to 0.88 mu g/kg/day for the 5(th) and 95(th) percentile, respectively. Children aged between 1-2 years had the highest acrylamide exposure (median 0.75 mu g/kg/day, 95(th) percentile 1.41 mu g/kg/day). For the peripheral neuropathy and neoplastic effects, the median MOE estimated was 1140 and 451, respectively. Men compared to women had a higher acrylamide dietary exposure, as well as smokers compared to non-smokers. Elderly and less educated individuals were inversely associated with acrylamide exposure. 'Bread and rusks' (24.2%) were the main source of acrylamide, followed by 'coffee' (21.3%). The current dietary exposure to acrylamide in the Portuguese population is of concern mainly regarding neoplastic effects. Our results point to the need to reduce exposure to acrylamide, especially in men, young children, higher educated individuals and smokers.

Dados da publicação

ISSN/ISSNe:
1944-0049, 1944-0049

FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT  Taylor and Francis Ltd.

Tipo:
Article
Páginas:
888-900
Link para outro recurso:
www.scopus.com

Citações Recebidas na Web of Science: 5

Citações Recebidas na Scopus: 9

Documentos

  • Não há documentos

Métricas

Filiações mostrar / ocultar

Keywords

  • Food contaminants; food processing; usual daily exposure; risk assessment; survey; safety

Financiamento

Proyectos asociados

Tracking the acquisition of eating habits in children and its effects on behaviours related to appetite

Investigador Principal: Carla Maria de Moura Lopes

Estudo Clínico Académico . 2019

Citar a publicação

Partilhar a publicação