Portal de investigação
Deoxynivalenol exposure assessment through a modelling approach of food intake and biomonitoring data-A contribution to the risk assessment of an enteropathogenic mycotoxin
Data de publicação:
Data Ahead of Print:
Autores da FMUP
Participantes de fora da FMUP
- Martins, C.
- Torres, D.
- Goios, A.
- Assunçao, R
- Alvito, P.
- Vidal, A.
- De Boevre, M.
- De Saeger, S.
- Nunes, C.
Unidades de investigação
Abstract
Deoxynivalenol (DON), an enteropathogenic mycotoxin produced by Fusarium species, is usually associated with adverse health outcomes such as gastrointestinal diseases and immunotoxicity. To estimate DON exposure of the Portuguese population at national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering the inputs of the food consumption data generated within the National Food and Physical Activity Survey and the human biomonitoring data used to assess the exposure to DON. Ten models of association between DON urinary biomarkers and food items (pasta, cookies, biscuits, sweets, bread, rusks, nuts, oilseeds, beer, meat, milk) were established. Applying the most adequate model to the consumption data (n = 5811) of the general population, the exposure estimates of the Probable Daily Intake revealed that a fraction (0.1%) of the Portuguese population might exceed the Tolerable Daily Intake defined for DON. The analysis stratified by age revealed children (3.2%) and adolescents (6.0%) are more likely to exceed the Tolerable Daily Intake for DON. Although the unavoidable uncertainties, these results are important contributions to understand the exposure to this mycotoxin in Portugal, to assess the associated risk and the potential public health consequences.
Dados da publicação
- ISSN/ISSNe:
- 0963-9969, 1873-7145
- Tipo:
- Article
- Páginas:
- 109863-
- Link para outro recurso:
- www.scopus.com
Food Research International Elsevier Ltd.
Citações Recebidas na Web of Science: 12
Citações Recebidas na Scopus: 14
Documentos
- Não há documentos
Filiações
Keywords
- Modelling; Mycotoxins; Food consumption; Urinary biomarkers; Public health
Financiamento
Proyectos asociados
Tracking the acquisition of eating habits in children and its effects on behaviours related to appetite
Investigador Principal: Carla Maria de Moura Lopes
Estudo Clínico Académico . 2019
Citar a publicação
Martins C,Torres D,Lopes C,Correia D,Goios A,Assunçao R,Alvito P,Vidal A,De Boevre M,De Saeger S,Nunes C. Deoxynivalenol exposure assessment through a modelling approach of food intake and biomonitoring data-A contribution to the risk assessment of an enteropathogenic mycotoxin. Food Res. Int. 2021. 140. p. 109863-109863. IF:7,425. (1).
