Portal de investigação
Food Consumption Data as a Tool to Estimate Exposure to Mycoestrogens
Data de publicação:
Autores da FMUP
Participantes de fora da FMUP
- Martins, C
- Torres, D
- Goios, A
- Assunçao, R
- Alvito, P
- Vidal, A
- De Boevre, M
- De Saeger, S
- Nunes, C
Unidades de investigação
Abstract
Zearalenone and alternariol are mycotoxins produced by Fusarium and Alternaria species, respectively, that present estrogenic activity and consequently are classified as endocrine disruptors. To estimate the exposure of the Portuguese population to these two mycotoxins at a national level, a modelling approach, based on data from 94 Portuguese volunteers, was developed considering as inputs: i) the food consumption data generated within the National Food and Physical Activity Survey; and ii) the human biomonitoring data used to assess the exposure to the referred mycotoxins. Six models of association between mycoestrogens urinary levels (zearalenone, total zearalenone and alternariol) and food items (meat, cheese, and fresh-cheese, breakfast cereals, sweets) were established. Applying the obtained models to the consumption data (n = 5811) of the general population, the median estimates of the probable daily intake revealed that a fraction of the Portuguese population might exceed the tolerable daily intake defined for zearalenone. A reference intake value for alternariol is still lacking, thus the characterization of risk due to the exposure to this mycotoxin was not possible to perform. Although the unavoidable uncertainties, these results are important contributions to understand the exposure to endocrine disruptors in Portugal and the potential Public Health consequences.
Dados da publicação
- ISSN/ISSNe:
- 2072-6651, 2072-6651
- Tipo:
- Article
- Páginas:
- -
- Link para outro recurso:
- www.scopus.com
Toxins Multidisciplinary Digital Publishing Institute (MDPI)
Citações Recebidas na Web of Science: 9
Citações Recebidas na Scopus: 13
Documentos
- Não há documentos
Filiações
Keywords
- modelling; mycotoxins; food consumption; urinary biomarkers; public health
Financiamento
Proyectos asociados
Tracking the acquisition of eating habits in children and its effects on behaviours related to appetite
Investigador Principal: Carla Maria de Moura Lopes
Estudo Clínico Académico . 2019
Citar a publicação
Martins C,Torres D,Lopes C,Correia D,Goios A,Assunçao R,Alvito P,Vidal A,De Boevre M,De Saeger S,Nunes C. Food Consumption Data as a Tool to Estimate Exposure to Mycoestrogens. Toxins. 2020. 12. (2):118. IF:4,546. (1).
