Pharmacokinetics and Pharmacodynamics of Dextromethorphan: Clinical and Forensic Aspects

Dados básicos

Código:
Estudo Clínico Académico
Protocolo:
Estudo Clínico Académico
EUDRACT:
NCT:
Centro:
Dotação:
Ano de início:
2020
Ano de conclusão:
Estudos observacionais Nacional Não Financiado Outros

Objectivos do projeto

Estudos Observacionais (STROBE statement); Natureza do Promotor: Academia – Tipo não comercial – Iniciativa do Investigador; Tipo de Centro: Unicêntrico – Cuidados Secundários

Documentos

  • Não há documentos

Participantes

Unidades de investigação

Stakeholders - Promotores

FMUP

Outputs do ensaio clínico


``Not everything that can be counted counts'' in ethanol toxicological results: an antemortem and postmortem technical interpretation focusing on driving under the influence

Review. 10.1093/fsr/owae023. 2024

  • Open Access.

Postmortem biochemical changes in multiple rat biological matrices and their correlation with the time of death

Meeting Abstract. 10.1016/j.toxlet.2022.07.277. 2022


20 years of real-world data to estimate chronic kidney disease prevalence and staging in an unselected population

Magalh?es, S.; (...); Dinis, R.

Article. 10.1093/ckj/sfac206. 2022

  • Open Access.

20 Years of Real-World Data to Estimate the Prevalence of Heart Failure and Its Subtypes in an Unselected Population of Integrated Care Units

Gavina, C.; (...); Taveira Gomes, T.

Article. 10.3390/jcdd9050149. 2022

  • Open Access.

20 Years of Real-World Data to Estimate the Prevalence of Heart Failure and Its Subtypes in an Unselected Population of Integrated Care Units.

Article. 2022


A soil-based approach on human taphonomy from five Portuguese public cemeteries

Article. 10.1080/00450618.2023.2289378. 2023


A Suicide Attempt with a Velo-Dog Pocket Revolver in an Alleged Victim of Carjacking

Article. 10.3390/forensicsci2010008. 2022

  • Open Access.

Acute liver failure requiring transplantation: A possible link to ulipristal acetate treatment?

Dinis, R., Vieira, DN

Article. 10.1111/bcpt.13631. 2021


An Overview of the Recent Advances in Antimicrobial Resistance

Review. 10.3390/microorganisms12091920. 2024

  • Open Access.

An Updated Review on the Psychoactive, Toxic and Anticancer Properties of Kava

Soares, RB, Dinis, R., Oliveira, NG

Article. 10.3390/jcm11144039. 2022

  • Open Access.

An Updated Review on the Psychoactive, Toxic and Anticancer Properties of Kava.

Review. 2022


Analysis of the autopsy, toxicological, and psychiatric reports of Portugal's first major forensic case: part III

Dinis, R.

Article. 10.1080/20961790.2021.1898079. 2021

  • Open Access.

Another suicide by sodium nitrite and multiple drugs: an alarming trend for "exit"?

Durao, C, Pedrosa, F, Dinis-Oliveira, RJ

Editorial Material. 10.1007/s12024-020-00340-2. 2021


Assessment of the CYP450 inhibitory activity of psilocybin, psilocin, LSD, 5-MeO-DMT and mescaline: An in vitro study

Meeting Abstract. 2023


Ayahuasca and N,N-dimethyltryptamine (DMT): Toxicokinetics, toxicodynamics, and biological effects

Meeting Abstract. 10.1016/j.toxlet.2022.07.282. 2022


Bisphosphonates and osteonecrosis of the jaws: Clinical and forensic aspects

Nogueira, D, Caldas, IM, Dinis, R.

Article. 10.1016/j.archoralbio.2023.105792. 2023

  • Open Access.

Cardiorenal Syndrome and Death Risk in Heart Failure or CKD Patients: An Urgent Call for Action

Meeting Abstract. 2022


Cardiorenal Syndrome and Kidney Disease Progression in Patients With Heart Failure or CKD: Is the Heart Leading the Way?

Meeting Abstract. 2022


Cardiovascular Risk Profile and Lipid Management in the Population-Based Cohort Study LATINO: 20 Years of Real-World Data

Gavina, C.; (...); Taveira Gomes, T.

Article. 10.3390/jcm11226825. 2022

  • Open Access.

Clinical and forensic aspects of potassium iodide: Suddenly in high demand across Europe due to fears of radiation poisoning from a nuclear attack in Ukraine

Review. 10.1111/bcpt.14052. 2024


Clinical and Forensic Aspects of the Different Subtypes of Argyria

Mota, L, Dinis-Oliveira, RJ

Review. 10.3390/jcm10102086. 2021

  • Open Access.

Clinical and Forensic Signs Resulting from Exposure to Heavy Metals and Other Chemical Elements of the Periodic Table

Machado, CD, Dinis, R.

Review. 10.3390/jcm12072591. 2023

  • Open Access.

Clinical and Forensic Signs Resulting from Exposure to Heavy Metals and Other Chemical Elements of the Periodic Table.

Review. 2023


Comment on Tomsia M. et al. Article "sodium nitrite detection in costal cartilage and vitreous humor - Case report of fatal poisoning with sodium nitrite"

Durao, C, Dinis-Oliveira, RJ

Article. 10.1016/j.jflm.2021.102200. 2021


Commentary on: Dean DE, Looman KB, Topmiller RG. Fatal methemoglobinemia in three suicidal sodium nitrite poisonings. J Forensic Sci. doi: 10.1111/1556-4029.14689. Epub 2021 Feb 17.

Dinis, R., Durao, C

Article. 10.1111/1556-4029.14723. 2021


Computerized delineation of the teeth and comparison with a smiling photograph: identification of a body skeletonized by cadaverous ichthyofauna action

Valente Aguiar, MS; (...); Dinis, R.

Editorial Material. 10.1007/s12024-021-00384-y. 2021


CRISPR-Cas technology in forensic investigations: Principles, applications, and ethical considerations

Article. 10.1016/j.fsigen.2024.103163. 2025

  • Open Access.

ChatGPT in forensic sciences: a new Pandora’s box with advantages and challenges to pay attention.

Article. 2023


ChatGPT in forensic sciences: a new Pandora's box with advantages and challenges to pay attention

Dinis, R., Azevedo, RMS

Article. 10.1093/fsr/owad039. 2023

  • Open Access.

Chemical elemental composition and human taphonomy: A comparative analysis between skeletonised and preserved individuals from six Portuguese public cemeteries

Article. 10.1016/j.jtemb.2024.127551. 2024

  • Open Access.

Digital Health and Big Data Analytics: Implications of Real-World Evidence for Clinicians and Policymakers

Magalh?es, T., Dinis, R., Taveira Gomes, T.

Article. 10.3390/ijerph19148364. 2022

  • Open Access.

Early pathways of toxicity triggered by 3,4-methylene-dioxypyrovalerone unveiled by in vivo toxicometabolomics

Meeting Abstract. 2021


Enhancing Immunotherapy in Ovarian Cancer: The Emerging Role of Metformin and Statins

Review. 10.3390/ijms25010323. 2024

  • Open Access.

Epigenomic mediation after adverse childhood experiences: a systematic review and meta-analysis

Neves, I, Dinis, R., Magalhaes, T

Review. 10.1080/20961790.2019.1641954. 2021

  • Open Access.

Fatal iatrogenic cardiac tamponade due to central venous catheterization

Valente Aguiar, MS; (...); Dinis, R.

Article. 10.1007/s12024-022-00491-4. 2022


Forensic significance of postmortem pink teeth: A narrative review

Review. 10.1016/j.archoralbio.2024.106092. 2025

  • Open Access.

Genetic toxicology and toxicokinetics of arecoline and related areca nut compounds: an updated review

Oliveira, NG, Ramos, DL, Dinis, R.

Review. 10.1007/s00204-020-02926-9. 2021


Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021

Article. 10.1016/S0140-6736(24)00367-2. 2024

  • Open Access.

Greenish-blue discoloration of the brain and heart after treatment with methylene blue

Durao, C, Pedrosa, F, Dinis, R.

Article. 10.1007/s12024-020-00316-2. 2020


Health Outcomes in Women Victims of Intimate Partner Violence: A 20-Year Real-World Study

Clemente-Teixeira, M; (...); Taveira Gomes, T.

Article. 10.3390/ijerph192417035. 2022

  • Open Access.

Health Outcomes in Women Victims of Intimate Partner Violence: A 20-Year Real-World Study.

Article. 2022


Immune Tumor Microenvironment in Ovarian Cancer Ascites

Almeida-Nunes, DL; (...); Ricardo, S

Review. 10.3390/ijms231810692. 2022

  • Open Access.

Immune Tumor Microenvironment in Ovarian Cancer Ascites.

Review. 2022


In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)

Araújo, AM; (...); Carvalho, F.

Article. 10.1007/s00204-020-02949-2. 2021


Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis

Article. 10.1111/imm.13686. 2023


Looking back, thanking authors and reviewers, and envisioning the future of RevSALUS

Dinis, R.; (...); Conde, J

Article. 10.51126/revsalus.v4i1.226. 2022


Looking back, thanking authors and reviewers, and envisioning the future of RevSALUS.

Article. 2022


Magic mushrooms and psilocybin: pharmacokinetics, pharmacodynamics, and clinical applications

Meeting Abstract. 10.1016/j.toxlet.2022.07.283. 2022


Metabolomics and proteomics in occupational medicine: a comprehensive systematic review

Review. 10.1186/s12995-024-00436-3. 2024

  • Open Access.

Metformin Impairs Linsitinib Anti-Tumor Effect on Ovarian Cancer Cell Lines

Article. 10.3390/ijms252211935. 2024

  • Open Access.

No Boundaries for Toxicology in Clinical Medicine: One Health, One Society and One Planet for All of Us

Dinis, R.

Editorial Material. 10.3390/jcm12082808. 2023

  • Open Access.

Nutritional adjuvants with antioxidant properties in the treatment of canine leishmaniasis

Gonçalves, RD; (...); Barrouin-Melo, SM

Article. 10.1016/j.vetpar.2021.109526. 2021


One image is value more than a thousand words: producing an atlas of medical signs for teaching clinical and forensic toxicology

Meeting Abstract. 10.1016/j.toxlet.2022.07.269. 2022


One image is worth more than a thousand words: producing an atlas of medical signs for teaching clinical and forensic toxicology

Dinis, R.

Article. 10.1080/20961790.2022.2059837. 2022

  • Open Access.

Os resultados positivos versus os resultados negativos em ci?ncia: uma breve reflex?o em benef?cio da integridade cient?fica

Dinis, R.AB -

Article. 10.51126/revsalus.v2i2.128. 2021


Ovarian cancer ascites proteomic profile reflects metabolic changes during disease progression

Article. 10.1016/j.bbrep.2024.101755. 2024

  • Open Access.

Overview of Synthetic Cannabinoids ADB-FUBINACA and AMB-FUBINACA: Clinical, Analytical, and Forensic Implications

Lobato-Freitas, C; (...); Dias-da-Silva, D

Review. 10.3390/ph14030186. 2021

  • Open Access.

Paving the way forward: Escherichia coli bacteriophages in a One Health approach

Oliveira, A; (...); Oliveira, H

Article. 10.1080/1040841x.2022.2161869. 2023


Pharmacokinetics and Pharmacodynamics of Salvinorin A and Salvia divinorum: Clinical and Forensic Aspects

Brito da Costa, AM; (...); Madureira Carvalho, A

Review. 10.3390/ph14020116. 2021

  • Open Access.

Pharmacokinetics, toxicological and clinical aspects of ulipristal acetate: insights into the mechanisms implicated in the hepatic toxicity

Dinis, R.

Article. 10.1080/03602532.2021.1917599. 2021


Postmortem degradation of mRNA transcripts in rat tissues and their correlation with time of death

Meeting Abstract. 2023


Predatory journals and meetings in forensic sciences: what every expert needs to know about this "parasitic" publishing model

Dinis-Oliveira, RJ

Article. 10.1080/20961790.2021.1989548. 2021

  • Open Access.

Preface

Article. 10.2174/258997751601230903010232. 2024


Premature Mortality in Type 2 Diabetes Mellitus Associated with Heart Failure and Chronic Kidney Disease: 20 Years of Real-World Data

Gavina, C.; (...); Taveira Gomes, T.

Article. 10.3390/jcm11082131. 2022

  • Open Access.

Premature Mortality in Type 2 Diabetes Mellitus Associated with Heart Failure and Chronic Kidney Disease: 20 Years of Real-World Data.

Article. 2022


Raising Awareness on the Clinical and Forensic Aspects of Jellyfish Stings: A Worldwide Increasing Threat

Cunha, SA, Dinis, R.

Review. 10.3390/ijerph19148430. 2022

  • Open Access.

Raising Awareness on the Clinical and Forensic Aspects of Jellyfish Stings: A Worldwide Increasing Threat.

Review. 2022


Reconstructed Human Epidermis: An Alternative Approach for In Vitro Bioequivalence Testing of Topical Products

Agonia, AS; (...); Palmeira-de-Oliveira, R

Article. 10.3390/pharmaceutics14081554. 2022

  • Open Access.

Reconstructed Human Epidermis: An Alternative Approach for In Vitro Bioequivalence Testing of Topical Products.

Article. 2022


Repeated Administration of Clinically Relevant Doses of the Prescription Opioids Tramadol and Tapentadol Causes Lung, Cardiac, and Brain Toxicity in Wistar Rats

Barbosa, J; (...); Dinis, R.

Article. 10.3390/ph14020097. 2021

  • Open Access.

Reply to the commentary by Sarode and Sarode on "Genetic toxicology and toxicokinetics of arecoline and related areca nut compounds: an updated review"

Oliveira, NG, Ramos, DL, Dinis-Oliveira, RJ

Article. 10.1007/s00204-021-03039-7. 2021

  • Open Access.

Simultaneous detection and quantification of psilocybin and psilocin by gas chromatography coupled to mass spectrometry (GC-MS)

Meeting Abstract. 10.1016/j.toxlet.2022.07.280. 2022


Single-camera photogrammetry using a mobile phone for low-cost documentation of corpses

Article. 10.1007/s00414-024-03271-7. 2024


The Auto-Brewery Syndrome: A Perfect Metabolic "Storm" with Clinical and Forensic Implications

Dinis, R.

Review. 10.3390/jcm10204637. 2021

  • Open Access.

The Future Is Now: Unraveling the Expanding Potential of Human (Necro)Microbiome in Forensic Investigations

Cláudia-Ferreira, A; (...); Freitas, AR

Review. 10.3390/microorganisms11102509. 2023

  • Open Access.

The Future Is Now: Unraveling the Expanding Potential of Human (Necro)Microbiome in Forensic Investigations.

Review. 2023


The Link Between Paraquat and Demyelination: A Review of Current Evidence

Review. 10.3390/antiox13111354. 2024

  • Open Access.

Toxicokinetics and Toxicodynamics of Ayahuasca Alkaloids N,N-Dimethyltryptamine (DMT), Harmine, Harmaline and Tetrahydroharmine: Clinical and Forensic Impact

Brito da Costa, AM; (...); Madureira Carvalho, A

Review. 10.3390/ph13110334. 2020

  • Open Access.

Tramadol and Tapentadol Induce Conditioned Place Preference with a Differential Impact on Rewarding Memory and Incubation of Craving

Barbosa, J; (...); Faria, J

Article. 10.3390/ph16010086. 2023

  • Open Access.

Tramadol and Tapentadol Induce Conditioned Place Preference with a Differential Impact on Rewarding Memory and Incubation of Craving.

Article. 2023


Unraveling the Hippocampal Molecular and Cellular Alterations behind Tramadol and Tapentadol Neurobehavioral Toxicity

Article. 10.3390/ph17060796. 2024

  • Open Access.

When the antidote for cyanide poisonings becomes a nightmare: an alarming outbreak of suicides using kits containing sodium nitrite

Dinis, R., Durao, C

Article. 10.1093/fsr/owad015. 2023

  • Open Access.

Argyria: A Review With Emphasis On The Clinical And Forensic Aspects

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Argyria: A Review With Emphasis On The Clinical And Forensic Aspects

Dissertação de Mestrado

Colaboradores: Ricardo Jorge Dinis Oliveira


Bisphosphonates And Osteonecrosis Of The Jaws: Clinical And Forensic Aspects.

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Clinical And Forensic Aspects Of Bromism: Manifestations And Treatment

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Clinical And Forensic Aspects Of Ibogaine

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Clinical And Forensic Aspects Of Ibogaine

Dissertação de Mestrado

Colaboradores: Ricardo Jorge Dinis Oliveira


Clinical And Forensic Aspects Of Jellyfish Stings

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Clinical And Forensic Aspects Of Jellyfish Stings

Dissertação de Mestrado

Colaboradores: Ricardo Jorge Dinis Oliveira


Clinical And Forensic Aspects Of Pharmacobezoars

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Clinical And Forensic Aspects Of Pharmacobezoars

Dissertação de Mestrado

Colaboradores: Ricardo Jorge Dinis Oliveira


Clinical And Forensic Signs Resulting From Exposure To Toxic Elements

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Clinical And Forensic Signs Resulting From Exposure To Toxic Elements

Dissertação de Mestrado

Colaboradores: Ricardo Jorge Dinis Oliveira


Inhalant Abuse: A New Psychoactive Trend With Clinical And Forensic Implications

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Inhalant Abuse: A New Psychoactive Trend With Clinical And Forensic Implications

Dissertação de Mestrado

Colaboradores: Ricardo Jorge Dinis Oliveira


Pharmacokinetic And Toxicological Aspects Of 1,3-Dimethylamilamine With Clinical And Forensic Impact

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Pharmacokinetics And Pharmacodynamics Of Buprenorphine: Relevant Clinical And Forensic Aspects

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Pharmacokinetics And Pharmacodynamics Of Buprenorphine: Relevant Clinical And Forensic Aspects

Dissertação de Mestrado

Colaboradores: Ricardo Jorge Dinis Oliveira


Pharmacokinetics And Pharmacodynamics Of Dextromethorphan: Clinical And Forensic Aspects

Trabalho final de curso

Colaboradores: Ricardo Jorge Dinis Oliveira


Pharmacokinetics And Pharmacodynamics Of Dextromethorphan: Clinical And Forensic Aspects

Dissertação de Mestrado

Colaboradores: Ricardo Jorge Dinis Oliveira


Technical Aspects Related To Harmonized Procedures For Photographic Registration In Forensic Autopisies

Tese de doutoramento

Colaboradores: Ricardo Jorge Dinis Oliveira


Toxicological Mechanisms Of Tramadol And Tapentadol: Biomedical And Forensic Insights From In Vivo Studies.

Tese de doutoramento

Colaboradores: Ricardo Jorge Dinis Oliveira


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