Portal de investigação
Unresolved inflammation and endothelitis in severe COVID-19 patients: identification of risk stratification biomarkers and therapeutic targets. (severe COVID-19)
Dados básicos
- Código:
- Estudo Clínico Académico (Severe COVID-19)
- Protocolo:
- Estudo Clínico Académico (Severe COVID-19)
- EUDRACT:
- NCT:
- Centro:
- FMUP - Faculdade de Medicina da Universidade do Porto
- Dotação:
- Ano de início:
- 2020
- Ano de conclusão:
Objectivos do projeto
Tipo de Estudo: Estudo Observacional – Iniciativa do Investigador; Natureza do Promotor: Academia – Tipo não comercial; Tipo de Centro: Unicêntrico – Centro de Ensaio: CHUSJ; Doença investigada:Covid-19 – Participantes recrutados: 100
Documentos
- Não há documentos
Participantes
Unidades de investigação
Stakeholders - Promotores
Outputs do ensaio clínico
ACE and ACE2 catalytic activity in the fecal content along the gut
Ferreira-Duarte, M; (...); Morato, M
Article. 10.1111/nmo.14598. 2023
Adenosine A2A and A3 Receptors as Targets for the Treatment of Hypertensive-Diabetic Nephropathy
Patinha, D; (...); Morato, M
Article. 10.3390/biomedicines8110529. 2020
Angiotensin-converting enzymes 1 and 2 in the feces: presence and catalytic activity in the rat 2,4,6-trinitrobenzene sulfonic acid-induced model of colitis
Ferreira Duarte, M; (...); Morato, M
Article. 10.1111/jgh.16541. 2024
Assessing MR-compatibility of somatosensory stimulation devices: a systematic review on testing methodologies (vol 17, 1071749, 2023)
Travassos, Carolina; (...); Castelo-Branco, Miguel
Correction. 10.3389/fnins.2024.1423928. 2024
Association between blood pressure and angiotensin-converting enzymes activity in prepubertal children*
Gaspar, AR; (...); Correia-Costa, L
Article. 10.1097/HJH.0000000000003345. 2023
Effects of NADPH Oxidase Isoform-2 (NOX2) Inhibition on Behavioral Responses and Neuroinflammation in a Mouse Model of Neuropathic Pain
Teixeira Santos, L; (...); Pinho, D.
Article. 10.3390/biomedicines11020416. 2023
Endocan: A novel biomarker for risk stratification, prognosis and therapeutic monitoring in human cardiovascular and renal diseases
Bessa, J; (...); Sousa, T.
Article. 10.1016/j.cca.2020.07.041. 2020
Endothelitis profile in acute heart failure and cardiogenic shock patients: Endocan as a potential novel biomarker and putative therapeutic target
Reina Couto, M; (...); Sousa, T.
Article. 10.3389/fphys.2022.965611. 2022
Evaluation of urinary cysteinyl leukotrienes as biomarkers of severity and putative therapeutic targets in COVID-19 patients
Reina-Couto, M; (...); Sousa, T.
Article. 10.1007/s00011-022-01682-z. 2023
Exergame-based rehabilitation for cancer patients undergoing abdominal surgery: Effects on pain, anxiety, depression, and fatigue - A pilot study
Alves, Isabel; (...); Magalhaes, Bruno
Article. 10.1016/j.ejon.2024.102665. 2024
Gender-related differences in cardiometabolic risk factors and oxidative stress among prepubertal children with obesity
Godinho, N; (...); Correia Costa, L
Article. 10.1515/jpem-2023-0286. 2024
How Far can Hydrogen Peroxide Travel in Microcirculation?
Sousa, T., Travasso, R., Salvador, A.
Meeting Abstract. 2021
Impact of Exergames on the Rehabilitation of Cancer Patients Undergoing Major Abdominal Surgery
Alves, Isabel; (...); Fernandes, Carla Silvia
Article. 10.1097/NCC.0000000000001331. 2024
Impact of physical activity on redox status and nitric oxide bioavailability in nonoverweight and overweight/obese prepubertal children
Leite Almeida, L; (...); Correia Costa, L
Article. 10.1016/j.freeradbiomed.2020.12.005. 2021
Inflammation in Human Heart Failure: Major Mediators and Therapeutic Targets
Reina Couto, M.; (...); Sousa, T.
Review. 10.3389/fphys.2021.746494. 2021
Inflammation in Human Heart Failure: Major Mediators and Therapeutic Targets.
Reina Couto, M; (...); Sousa, T
Review. 2021
Innovative business models as drivers for prosumers integration-Enablers and barriers
Botelho, D. F.; (...); Sousa, T.
Article. 10.1016/j.rser.2021.111057. 2021
Interaction between the Renin-Angiotensin System and Enteric Neurotransmission Contributes to Colonic Dysmotility in the TNBS-Induced Model of Colitis
Ferreira-Duarte, M; (...); Morato, M
Article. 10.3390/ijms22094836. 2021
Interrelationship between renin-angiotensin-aldosterone system and oxidative stress in chronic heart failure patients with or without renal impairment
Reina-Couto, M; (...); Sousa, T
Article. 10.1016/j.biopha.2020.110938. 2021
Lipoxin profiles in human acute heart failure and cardiogenic shock and their modulation by aspirin or statin therapy
Silva-Pereira, C; (...); Sousa, T
Meeting Abstract. 2020
Lipoxins Profile And FPR2/ALX Receptor Expression In Human Acute Heart Failure And Cardiogenic Shock
Reina-Couto, M; (...); Sousa, T
Meeting Abstract. 2023
Proinflammatory and endothelial activation profiles in hospitalized COVID-19 patients: impact of arterial hypertension and previous treatment with renin-angiotensin-aldosterone inhibitors
Silva-Pereira, PDC; (...); Sousa, T
Meeting Abstract. 2023
Proinflammatory cytokines and endothelial cell activation in human acute heart failure and cardiogenic shock
Couto, M; (...); Sousa, T
Meeting Abstract. 2020
Specialized proresolving mediators: Benefits within and beyond inflammation resolution in cardiometabolic, neurological and psychiatric disorders
Sousa, T.; (...); Verri, W
Editorial Material. 10.3389/fphys.2023.1176700. 2023
The flanking polyQ regions of Huntingtin exon 1 display distinct dynamic signatures in its membrane-bound state: insights into Huntington's disease
Sousa, T.; (...); Melo, A. M.
Meeting Abstract. 2022
The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice
Teixeira Santos, L; (...); Pinho, D.
Article. 10.1371/journal.pone.0287392. 2023
Two Tales of Rumination and Burnout: Examining the Effects of Boredom and Overload
Neves, Pedro, Sousa, Teresa
Meeting Abstract. 2023
Urinary Cysteinyl Leukotrienes as Biomarkers of Endothelial Activation, Inflammation and Oxidative Stress and Their Relationship with Organ Dysfunction in Human Septic Shock
Reina-Couto, M; (...); Sousa, T.
Article. 10.3390/biomedicines10112845. 2022
